Growing up, Dr. Raquel Salinas did not believe that someone like her could turn a passion for science into a career. It was the classes she encountered at the LBJ Science Academy, a magnet high school in Austin, Texas, that ultimately led her to a Bachelor of Science in Chemistry from the University of Texas at Austin. She then obtained a Master of Science in Biochemistry from Texas State University, and a Ph.D. in Pharmacology from Duke University. Dr.

To augment and expand upon the findings of the Nonhuman Primate Evaluation and Analysis Part 1: Analysis of Future Demand and Supply of the study, which was derived from historical analyses, supplier interviews, and user surveys, an expert panel forum was convened by the NIH on “Challenges in Assessing Nonhuman Primate (NHP) Needs and Resources for Biomedical Research.” A forum was conducted August 23–24, 2018, and brought together program officers from the NIH ICOs that sponsor the majority of NHP studies, leading researchers who use NHPs and represent a broad spectrum of scientific areas,

Nonhuman primates (NHPs) serve as critical animal models for many research areas, including infectious diseases; social, cognitive and behavioral research; reproductive biology; regenerative medicine; aging and neuroscience research. The National Institutes of Health (NIH) provides support for NHP breeding colonies, facilities, and other research resources to facilitate the effective use of NHPs by NIH grantees as well as intramural scientists.

Substance use disorders and neuropsychiatric conditions are brain diseases characterized by morphological and functional adaptations in neurons and neural circuits. Traditionally, neuroscientists use conventional confocal or electron microscopy to characterize how abused substances remodel sites of synaptic communication. However, confocal microscopy is hindered by diffraction limits of light waves and cannot resolve structures below a spatial resolution of about 250 nm.

The National Primate Research Centers (NPRCs)¹ Consortium is a collaboration among  the California (CNPRC), Oregon (ONPRC), Southwest (SNPRC), Tulane (TNPRC), Washington (WaNPRC), Wisconsin (WNPRC), and Emory (ENPRC) National Primate Research Centers. Funded by the Office of Research Infrastructure Programs (ORIP) of the National Institutes of Health (NIH), the Consortium’s mission is to improve global health through biomedical research with NHPs.

Research with non-human primates (NHPs)^1–4 is significant to our understanding of how the human body responds to diseases, some forms of cancers, organ transplantation, and how the human brain works. Although NHPs are fundamental to science and medicine, access to these animals and their related resources is limited. To alleviate this limitation, collaborative initiatives among research institutions have been established to increase access and promote sharing of invaluable resources among the scientific community.

Biomedical research with nonhuman primates (NHPs) has resulted in several notable medical breakthroughs.^1–5 NHP research has been essential to our understanding of how the human body responds to infectious and noninfectious diseases and organ transplantation, and to finding therapies for certain cancers and AIDS. NHP biomedical research is made more translatable to human disease using NHP-related laboratory reagents for the characterization and modulation of disease-causing processes.

Many of the scientific discoveries require an understanding of specialized biological processes at the cellular level. Scientists rely on the use of light microscopes to visualize cells and other organisms invisible to the human eye. To segregate cell populations from a heterogenous mixture and to quantitatively analyze cells from a variety of biological specimens, many scientists employ flow cytometry.

For more than 50 years, scientists have used the roundworm Caenorhabditis elegans (C. elegans)—a hermaphroditic nematode that is widely recognized as an important tool for genetics, cell biology, and neuroscience research. The entire adult nervous system and cell lineage of C. elegans was mapped in 19861 and since then, scientists have used this map of neuron connectivity to help elucidate diverse neurobiological mechanisms. Compared to the 100 billion neurons in the human brain, C.