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Funding Opportunities List

ORIP awards grants to support research-related resources and infrastructure, including animal models for human diseases, cutting-edge scientific instrumentation, construction and modernization of research facilities, and research training opportunities for veterinary scientists. Use the fields below or scroll down to explore open funding opportunities supported by ORIP. The table headers can be selected to sort the data alphabetically or chronologically. The Divisions in the last column refer to ORIP’s Division of Comparative Medicine (DCM), Division of Construction and Instruments (DCI), and Small Business (SB). If you have questions about the funding opportunities listed below, please contact ORIPoutreach@mail.nih.gov.

Title Funding Number Organization Funding Mechanism Description Expiration Date Division
INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21... RFA-OD-21-007 OD R21 07/04/2024 DCM
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed) RFA-NS-23-006 NINDS R43/R44 04/05/2025 SB
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed) RFA-NS-23-007 NINDS R41/R42 04/05/2025 SB
Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed) RFA-OD-22-013 ORIP R24 05/26/2025 DCM
Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed) PAR-22-204 ORIP R24 01/08/2025 DCM
Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 ... RFA-OD-22-009 OD R01 07/02/2024 DCM
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) PAR-22-060 NIDCR R15 01/08/2025 DCM
High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) PAR-22-079 ORIP S10 06/04/2024 DCI
Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) PAR-22-080 ORIP S10 06/04/2024 DCI
Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) PAR-22-081 ORIP S10 06/04/2024 DCI
Notice of Special Interest (NOSI): Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Model... NOT-OD-22-039 ORIP R21 05/08/2024 DCM
Development of Animal Models and Related Biological Materials for Down Syndrome Research (R24 Clinical Trials Not-Allowed) PAR-22-247 OD R24 05/26/2025 DCM
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 OD Admin Supp 09/10/2024 -
Screening and Functional Validation of Human Birth Defects Genomic Variants (R01 Clinical Trial Not Allowed) PAR-21-229 NICHD R01 05/08/2025 DCM
Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed) PAR-21-226 ORIP R41/R42 09/06/2024 SB
Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed) PAR-21-225 ORIP R43/R44 09/06/2024 SB
Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed) PAR-21-167 ORIP R21 05/08/2024 DCM
Notice of Special Interest (NOSI): Availability of Administrative Supplements for Childcare Costs for Ruth L. Kirschstein National Research Service Aw... NOT-OD-21-070 NIH Admin Supp 04/08/2024 -
Early Stage Investigator Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) PAR-21-109 NIA R21 05/08/2024 DCM
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) PA-20-190 NIH K01 05/08/2024 DCM
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) PA-20-188 NIH K99/R00 05/08/2024 DCM
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 NIH R01 05/08/2024 DCM
Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed) PAR-23-126 ORIP P51 05/26/2026 DCM
Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed) PAR-24-078 ORIP U42 01/08/2027 DCM
Limited Competition: Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed) PAR-24-105 ORIP U42 09/02/2024 DCM
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) PAR-24-075 OD R01 12/29/2026 DCM
Limited Competition: Development and Renovation of Facilities for Expanding the Breeding Capacity of Specific Pathogen Free Non-Human Primates to Supp... PAR-24-033 ORIP C06 01/08/2025 DCI
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (... NOT-OD-23-170 ORWH Admin Supp 10/09/2026 -
PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed... PA-23-232 NIH R41/R42 04/06/2024 SB
PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Tria... PA-23-230 NIH R43/R44 04/06/2024 SB
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed) PA-23-189 OD Admin Supp 05/08/2026 -
HIV/AIDS Scholars Using Nonhuman Primate (NHP) Models Program (K01 Independent Clinical Trial Not Allowed) PAR-23-225 ORIP K01 09/08/2025 DCM
Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) PAR-23-215 ORIP R21 09/08/2025 DCM
Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed) PAR-24-129 ORIP U42 01/08/2027 DCM
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 NIGMS S10 06/03/2025 DCI
Limited Competition: Small Grant Program for ORIP Special Emphasis Research Career Award (SERCA) K01 Recipients (R03 Clinical Trials Not Allowed) PAR-23-127 ORIP R03 05/08/2026 DCM
Notice of Special Interest (NOSI): Revision Applications to add a Curation and Informatics Component to existing Animal and Biological Material Resour... NOT-OD-23-068 ORIP P40 01/08/2026 DCM
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) PA-23-048 NIH T32 05/08/2026 DCM
Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35) PA-23-080 NIH T35 05/08/2026 DCM
Mentored Career Development Program for Early Stage Investigators Using Nonhuman Primate Research Models (K01 Independent Clinical Trial Not Allowed) PAR-23-073 NIAID K01 01/08/2026 DCM
Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed) RFA-OD-23-001 ORIP P40 01/08/2026 DCM
Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trials Not Allowed) PAR-23-067 OD R21 01/08/2026 DCM
Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R01) PAR-23-040 ORIP R01 07/06/2025 DCM
Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R24 Clini... PAR-23-039 ORIP R24 05/26/2025 DCM