Workshop Reports

Review the meeting summaries and reports below to find out what happened at events related to ORIP's mission and programs.

Comparative Medicine and Resource Related Reports

View the latest comparative medicine and resource related reports to see how animal models are furthering clinical and translational research and Resources are managed to maximize efficiency. Visit Archived Workshop Reports to view reports from before the last 5 years.

2017

Tagging and Identification of Animal Resources Workshop

September 6, 2017

On September 6, 2017, the Office of Research Infrastructure Programs (ORIP) at National Institutes of Health (NIH) convened a workshop on the “Tagging and Identification of Animal Resources.” The goals of the workshop were to provide participants with (1) a thorough review of the current challenges and possible solutions for the reporting and unique identification of research resources, including model organisms used in biomedical research; (2) an overview of the Resource Identification Initiative (RII or Initiative) to create and maintain biological resource identifiers for NIH-supported animal repositories; and (3) a hands-on session for Resource Directors and NIH staff on acquisition and use of unique Research Resource Identifiers (RRIDs) to identify research resources and conduct citation analysis of their usage. Participants included representatives from academia, industry, and publishing. 

Cryopreservation of Aquatic Biomedical Models

January 7, 2017

The Cryopreservation of Aquatic Biomedical Models Workshop was held on January 7, 2017 in Birmingham, Alabama. Aquatic animal species such as zebrafish, medaka, Xiphophorus, and Xenopus are increasingly valuable to biomedical researchers because they provide critical clues to the biological mechanisms that underlie human health and disease. Although considerable resources have been invested to generate transgenic, knockout, and mutant lines of many of those aquatic species, reliable and cost-effective approaches for long-term preservation of these valuable lines are still lacking. Currently, cryopreservation of sperm is the sole and proven method for the long-term maintenance in many aquatic models, with no other approaches available to aquatic researchers. To address this gap, the National Institute of Health’s Office of Research Infrastructure Programs (ORIP) sponsored a workshop, whose objectives were to (1) assess the status of germplasm cryopreservation in various aquatic models; (2) identify the obstacles, opportunities, and priorities that may address the need for improved methods; and (3) evaluate novel and emerging research and technologies that might lead to the successful preservation of other germplasm formats. Approximately 25 participants, including experts in the field of cryopreservation of aquatic models, representing the cryopreservation scientific community at large attended the workshop, despite the severe weather that affected the area where the workshop was held. Discussions during the different sessions resulted in specific, actionable recommendations to ORIP, as described in the accompanying report.

2016

Cryopreservation of Drosophila Strains

July 13, 2016

Drosophila melanogaster is widely used in the biomedical research community to study development, model human diseases and undertake high-throughput drug discovery. However, reliable and cost-effective approaches for long-term preservation of Drosophila stocks are lacking. To address this gap, the Office of Research Infrastructure Programs in the Division of Program Coordination, Planning and Strategic Initiatives and the National Institute of Neurological Diseases and Stroke co-sponsored a workshop titled “Cryopreservation of Drosophila Strains” in Orlando, Florida on July 13, 2016. The objective of this workshop was to evaluate the potential and practicality of developing efficient preservation methods for long-term storage of Drosophila stocks.

2015

Linking Disease Model Phenotypes to Human Conditions Symposium

September 10, 2015 to September 11, 2015

The Office of Research Infrastructure Programs in the Division of Program Coordination, Planning, and Strategic Initiatives convened on September 10-11, 2015 a Symposium titled “Linking Disease Model Phenotypes to Human Conditions” at the Fishers Lane Conference Center, Rockville, MD. Over 120 participants, including 58 NIH representative from 16 Institutes and Centers, attended the meeting. Among participants were foreign scientists, representatives from other government agencies, such as FDA and US Army, and the biotech and pharma industry. The purpose of the Symposium was to discuss the current status of phenomics and its role in closing the gap that exists between biomedical research and clinical medical practice.

Summary of the 16th Annual Merial-NIH National Veterinary Scholars Symposium

July 30, 2015 to August 2, 2015

Over 600 participants attended the 16th annual Merial-NIH Symposium at the campus of UC Davis, California, hosted by the College of Veterinary Medicine.  More than 450 veterinary students from 33 academic institutions were represented at the symposium, including 26 veterinary colleges from the United States, two from Canada, and two from Europe as well as five other research centers and universities, including NCI/NIH. Other participants included University Program Directors and representatives from the NIH, Merial, Burroughs Wellcome, the Association of American Veterinary Colleges, the American Veterinary Medical Association (AVMA), and the Howard Hughes Medical Institute. Students attending the symposium included veterinary students participating in summer research programs as well as DVM/PhD students and postdoctoral veterinarians in research training programs. The symposium theme of “Solving Complex Challenges at the Interface of Humans, Animal and their Environment” emphasized the impact of the One Health concept on local, national and global sustainability as well as human and animal health and scientific discovery.

One Health: Integrating the Veterinarian Scientist into the Biomedical Research Enterprise

April 7, 2015 to April 8, 2015

On April 7–8, 2015, the Office of Research Infrastructure Programs (ORIP) in the Division of Program Coordination, Planning, and Strategic Initiatives, sponsored a workshop on the NIH campus entitled, One Health: Integrating the Veterinarian Scientist into the Biomedical Research Enterprise.  One Health is defined as the integrative effort of multiple disciplines working together to attain optimal health for people, animals and the environment. The purpose of the workshop was to identify how the concept of One Health can advance the NIH mission in regard to both basic and applied research, including training of the biomedical work force, concentrating on the veterinarian scientist.

2014

The Medaka Model for Comparative Assessment of Human Disease Mechanisms

December 18, 2014

The Medaka Model for Comparative Assessment of Human Disease Mechanisms Workshop was held on December 18, 2014 in Austin, Texas. The central purpose of this workshop was to assess current use and to project the future resource needs of the American medaka research community. The workshop sought to spur discussions of issues that would promote more informative comparative disease model studies. Finally, workshop attendees met together to propose, discuss, and agree on recommendations regarding the most effective research resources needed to enable scientists in the United States to perform experiments leading to impacting experimental results directly relevant in human disease research.

2014 Merial-NIH National Veterinary Scholars Symposium "One Health"

July 31, 2014 to August 3, 2014

More than 460 veterinary students from 45 academic institutions were represented at the symposium, including 29 veterinary colleges from the United States, three from Canada, two from the Caribbean, four from Europe, and two from Australia as well as five other research centers and universities, including NCI, NIH. Other participants included University Program Directors and representatives from the NIH, Merial, Burroughs Wellcome, the Association of American Veterinary Colleges, the American Veterinary Medical Association (AVMA), and the Howard Hughes Medical Institute. Students attending the symposium included veterinary students participating in summer research programs as well as DVM/PhD students and postdoctoral veterinarians in research training programs. The symposium theme of “One Health” emphasized the impact of veterinary medicine on global sustainability as well as human and animal health and scientific discovery.

Animal Models Impacting Human Disease: Tenth Comparative Medicine Resource Directors Meeting

August 12, 2014 to August 13, 2014

“Animal Models Impacting Human Disease,” the Tenth Comparative Medicine Resource Directors Meeting, was held August 12-13, 2014, in Bethesda, Maryland. All Resource Directors funded by the Office of Research Infrastructure Programs (ORIP)/Division of Comparative Medicine (DCM) were invited to attend. This biannual meeting provides a forum to (1) Exchange new information, advances, and ideas among grantees and NIH staff members from several Institutes and Centers (ICs), (2) Increase collaborations and sharing among DCM-funded Resources and between these Resources and various NIH ICs, (3) Inform Resources and NIH staff about accomplishments and challenges, and (4) Identify Resource-related scientific advances on evolving animal-human correlations, emerging technologies, and reproducibility in animal models of human disease.

Summary of the 7th Aquatic Animal Models of Human Disease Conference

December 13, 2014 to December 18, 2014

The 7th Aquatic Animal Models of Human Disease Conference was organized by Dr. Ronald Walter (Texas State University) and was held on December 13-18, 2014 in Austin, Texas. Approximately a hundred scientists, junior faculty, students and postdoctoral researchers from academic institutions in 10 different countries (the USA, Canada, Japan, Germany, Hong Kong/China, Singapore, Taiwan, South Korea, Italy and Spain) attended the meeting. The meeting provided a forum to highlight scientific developments using aquatic species (natural and genetically engineered), as well as to discuss pressing topics that the aquatic research community consider important to advance the use of aquatic species as models for biomedical research. In general, the sessions covered the following research areas: Translational, Aquatic Genomes, Toxicology, Regeneration, Cancer, Developmental Disease, Stem Cell, Infectious Disease, Aging, Metabolic Disease and Aquatic Environments.

2013

From Tank to Bedside: Zebrafish and Translational Research

October 28, 2013 to October 29, 2013

On October 28 and 29, 2013, the NIH convened a workshop entitled, “From Tank to Bedside:  Zebrafish and Translational Research” on October 29 – 30, 2013 at the Natcher Conference Center on the NIH Campus.  The objectives of the Workshop were: 1)  to provide input to the NIH on the current status of projects and technologies that directly inform studies related to human health using the zebrafish as an animal model; and 2) to provide advice to the NIH on initiatives that can enhance the use of zebrafish in translational research.  For the purpose of the workshop, translational research was defined broadly as investigations that are directly related to aspects of human disease, with the eventual goal of finding the cause of illness and treating it in the clinic.

14th Annual Merial-NIH National Veterinary Scholars Symposium “Comparative Medicine: Meeting Global Needs"

August 1, 2013 to August 4, 2013

Over 600 participants attended the 13th annual Merial‐NIH Symposium at the Kellogg Center, East Lansing, Michigan, hosted by the College of Veterinary Medicine at Michigan State University. Over 435 veterinary students from 36 veterinary schools, including 27 from US institutions, three from Canada, two from the Caribbean, three from France, and one from Holland, were represented at the symposium as well as veterinary students training at NCI, NIH. Other participants included University Program Directors as well as representatives from the NIH, Merial, Burroughs Wellcome, the Association of American Veterinary Colleges, the American Veterinary Medical Association (AVMA), and the Howard Hughes Medical Institute. Students attending the symposium included veterinary students participating in the summer research program, DVM/PhD students and postdoctoral veterinarians in research training programs. The over‐riding theme of the symposium was “Comparative Medicine: Meeting Global Needs”.

Evaluation of the Special Emphasis Research Career Award (SERCA) Program (K01)

March 7, 2013

The Division of Comparative Medicine (DCM), within the Office of Research Infrastructure Programs (ORIP) / DPCPSI / NIH-OD, funds Special Emphasis Research Career Awards (SERCAs) in Pathology and Comparative Medicine. These K01 awards are intended specifically to assist graduate veterinarians who have experience in animal/comparative research to become independent investigators in areas related to biomedical science. Since its inception more than 30 years ago, an independent evaluation of the program has not been done. Therefore, in 2012 the DCM assessed the extent to which the program is achieving its original goals.

Animal Models and Personalized Medicine

October 28, 2013 to October 29, 2013

On October 28 and 29, 2013, the NIH convened a workshop entitled, “Animal Models and Personalized Medicine.” The goals of the workshop were: 1. to discuss the status of human personalized genomics and the use of comparative functional genomics in other organisms to interpret patient information for clinical use; 2. to review the current status of the development and use of the personalized animal models based upon a variety of animal species; 3. to evaluate the potential use of personalized animal models for translational medicine applications and; 4. to develop the consensus and provide recommendations to the NIH regarding the potential strategic initiatives which would make a valuable contribution to the field.