Welcome to ORIP

This notice of funding opportunity invites U54 cooperative agreement applications for the support and advancement of the Centers for Precision Disease Modeling. The goal of the Centers is to support collaborative research projects that bridge current personalized medicine efforts in human subjects with advances in animal genomics and genetic manipulation technologies.

Dr. Tammie Benzinger is uncovering the mysteries of Alzheimer’s disease using ORIP-supported resources. Her work recently led to FDA approval of a new drug designed to clear amyloid plaques in early symptomatic Alzheimer’s disease.

The Oklahoma Medical Research Foundation has been working toward a more inclusive, collaborative future by supporting research and training focused on health of Tribal Nations and other underrepresented minorities with community-centric and forward-thinking scientific initiatives.

S10 Post-Review Webinar: Register now to join our upcoming webinar on November 14 at 1:00 p.m. (EST) and learn about the review outcomes, your options, and the next steps from ORIP Program Officers. Principal Investigators of the FY 2025 applications and their delegates are highly encouraged to attend this webinar.

ORIP has issued a funding opportunity, PAR-25-061, to invite applications from eligible institutions to modernize existing or construct new biomedical research facilities. Applications from both research-intensive institutions and Institutions of Emerging Excellence in biomedical research from all geographic regions in the nation are strongly encouraged.

Dr. Hugo Bellen is an ORIP-funded researcher who uses the fruit fly (Drosophila melanogaster) as a model for neurological diseases. Dr. Bellen was recently recognized as the recipient of the 2024 Gruber Genetics Prize.

The Nonhuman Primate (NHP) Evaluation and Analysis, initiated at the request of ORIP and the Office of AIDS Research, provides an overview of the demand and supply of NHPs in the United States. This study covers usage trends from fiscal years 2018 to 2022 and provides a forecast of NHP usage for calendar years 2024 to 2028.

Register now to attend our workshop on the needs for cryopreservation and other preservation approaches for widely used animal models in biomedical research. Sessions will be held from September 2024 to May 2025.

ORIP participates in two federal Small Business grant programs—the Small Business Innovation Research (SBIR) and the Small Business Technology Transfer (STTR)—that provide seed funding to small businesses to develop technologies that have potential for commercialization.