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NIH Success Stories (supported by ORIP)

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Using Vibrations in Medical Devices

In engineering, an actuator turns a signal into mechanical action or motion. For example, actuators in your printer, in the form of electric motors, are what move the ink cartridge from side to side. Dr. Maureen L. Mulvihill, a materials scientist, earned her PhD researching piezoelectric materials...

microscopic view of collagen fibers

Utah Company Develops Research Tool to Detect Diseases Earlier and More Accurately

What do arthritis, osteoporosis, and some cancers have in common? They all show signs of tissue damage early on in their disease progression. But researchers and clinicians don’t have an easy way to detect this damage. If they did, diseases could be diagnosed earlier and more accurately.

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NIH Portfolio Company Showcase (supported by ORIP)

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3Helix

3Helix commercializes labeled collagen hybridizing peptide (CHP) that specifically binds to such unfolded collagen chains, enabling unlimited laboratory applications in pathology, biomechanics, cell biology, regenerative medicine, and more. 

Actuated Medical: Innovative motion, positive outcomes (logo)

Actuated Medical

The future looks brighter for 100M Americans living with neurological conditions and musculoskeletal disorders (e.g., Parkinson’s, stroke, urinary incontinence). These conditions significantly reduce patients’ quality of life and cost the healthcare system an estimated $800B annually.

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Combinati

Combinati believes simplicity shouldn’t require sacrificing robustness, quality or rigor – in fact, it should enable it. Our easy-to-use digital PCR platform offers absolute quantification to track disease-relevant biomarkers over time with high accuracy and precision.

CryoCrate, life in nano ice (logo)

CryoCrate

Cryopreservation is a critical platform technology for biomedical research and clinical applications. There are numerous cell and tissue types that (a) cannot be cryopreserved or (b) can be cryopreserved, but lose viability during the freeze-thaw process.

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Sarcomatrix

Sarcomatrix Therapeutics Corp. is a pioneering biopharmaceutical company dedicated to advancing novel therapeutics that leverage deep insights into muscle biology and tissue regeneration to address muscle-wasting diseases with high unmet needs.

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Bloomer Tech

Bloomer Tech is ushering in a new age of personalized healthcare. Using patented technology, they are addressing sex differences in cardiovascular care for women by using the Bloomer Tech-Augmented Garment (TAG), a wearable medical device that generates cardiovascular data insights and digital biomarkers.  

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InVivo Biosystems

InVivo Biosystems enables drug discovery and development in neurological, metabolic, and rare monogenic disease indications with its premiere proprietary platforms, RapidGen. RapidGen leverages -omic data and multiplexed CRISPR to speed target identification & multimodal therapeutics screening on highly relevant behavioral and molecular endpoints in vivo.  

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Lectenz Bio

Lectenz Bio is a company dedicated to providing and novel, effective glyco-research and bioprocessing tools. Our mission is to empower innovation by making glycoscience simple. We accomplish this goal by employing a strong team with diverse expertise in high performance computing and wet lab science. it is through this interdisciplinary approach that we developed our patented Lectenz® and GlycoSense platforms—offering new, easy to use ways to study glycobiology.

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