S10 Notices of Funding Opportunities

ORIP manages the S10 programs by issuing notices of funding opportunities (NOFOs) with one annual receipt date. Active NOFOs are listed below:

• Basic Instrumentation Grant Program (BIG) – The BIG Program funds grant awards in the $25,000 to $350,000 range. Deadline: June 2, 2025
• Shared Instrumentation Grant Program (SIG) – The SIG Program funds grant awards in the $50,000 to $750,000 range. Deadline: June 2, 2025
• High-End Instrumentation Grant Program (HEI) – The HEI Program funds grant awards in the $750,001 to $2,000,000 range. Deadline: June 2, 2025

Additional resources for S10 applicants are listed below:

• S10 Project Table Template
• Example S10 Application: Microscope*
• Example S10 Application: Mass Spectrometer*

*These documents are not yet fully compliant with Section 508 accessibility requirements. Section 508‑compliant versions will be posted as soon as they are available.