Programs and Activities Highlights
- Focus Group: Extramural Integrity Training Scenario and Case Study
An ORIP program official participated in a discussion on extramural integrity, including a breakout session, on May 20, 2025. The breakout session was intended to gather ideas for case studies, narratives, and scenarios related to extramural integrity. The goal of this effort was to compile a group of potential general extramural integrity case studies, narratives, and scenarios with transferable messaging across business areas. Focus group members consisted of NIH Staff Training Advisory Committee members, Office of Extramural Research staff, NIH institute and center officers, and training developers.
- Notice of ORIP Participation in PA-25-080, NIH Support for Conferences and Scientific Meetings (Parent R13, Clinical Trial Not Allowed)
ORIP published a notice to inform potential applicants that effective immediately, the office is participating in PA-25-080, NIH Support for Conferences and Scientific Meetings (Parent R13, Clinical Trial Not Allowed). The purpose of the NIH Research Conference Grant (R13) is to support high-quality conferences that are relevant to public health and to the scientific missions of participating institutes and centers. ORIP’s high-priority thematic areas are (1) developing models for human diseases, (2) accelerating research discoveries by providing access to state-of-the-art instrumentation, and (3) training and diversifying the biomedical workforce. For models-oriented conferences and meetings, proposals to be considered must be applicable to the research interests of two or more categorical NIH institutes or centers. For training-oriented conferences and meetings, applications with a primary focus on veterinary scientists as translational researchers will receive priority for consideration.
- NIH Research Festival
NIH’s Intramural Research Program hosted the annual NIH Research Festival, which highlights groundbreaking intramural science and provides an opportunity for the scientific community to share and connect. The festival took place on the NIH main campus in September 2024. ORIP presented two posters at the festival, in the category of research support services. One of the posters featured information on ORIP’s various resources (e.g., aquatic, rodent, nonhuman primate, biological materials and reagents, other comparative models). The other poster highlighted the critical infrastructure that ORIP supports through the S10 Shared Instrumentation Programs, as well as the impact that S10-supported instruments have on research across the United States.
- Oklahoma Medical Research Foundation Construction Supports Inclusive Immunology Research and Proactive Initiatives
ORIP published a research highlight in August 2024 featuring the Oklahoma Medical Research Foundation (OMRF). ORIP’s Extramural Construction Programs supported renovations to facilities for research in molecular immunology and genetics, cardiovascular biology, and autoimmune diseases at OMRF. With this funding, OMRF has been able to expand the breadth of its research, recruit exceptional scientists and trainees, and foster exciting collaborations across Oklahoma and the nation. OMRF has formed partnerships with local Tribes; as a result, OMRF and Tribal clinicians were able to identify better blood markers for the Oklahoma Tribal citizens and change the way that rheumatic diseases are screened for.
- S10-Funded Work Featured on Nature Genetics Cover
A recent paper, titled A common flanking variant is associated with enhanced stability of the FGF14-SCA27B repeat locus, was featured on the cover of the July 2024 issue of Nature Genetics. This international study describes a common flanking variant that is associated with enhanced stability of repeat locus. These findings offer insight into the mechanism protecting against tandem repeat expansion, a known cause of more than 40 neurological disorders, including schizophrenia. This work received support through ORIP’s S10 shared instrumentation programs (S10OD026880 and S10OD030463) and was performed using 1,027 samples from the NIH All of Us Research Program.
Read more in the archive.
Collaborations with Other NIH Institutes/Centers/Offices
- Collaboration with the INCLUDE Project for S10 Co-funding
In May 2025, ORIP staff participated in an NIH Down Syndrome Working Group meeting and presented to the representatives from other NIH units an S10 grant that has substantial usage to support research on Down syndrome. ORIP staff made a convincing case, which resulted in the first INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project co-funding of an S10 application, expanding the support of ORIP’s Shared Instrumentation Programs.
- ODSS Monthly Meeting: Institutional Data Science Supplement Awards
ORIP staff participated in a meeting with the NIH Office of Data Science Strategy (ODSS) to discuss institutional data science supplement awards on May 15, 2025. During this meeting, ORIP shared information regarding the S10 Shared Instrumentation Programs.
- National Primate Research Centers: Requesting and Allocation Procedures
ORIP, in collaboration with the National Primate Research Centers (NPRCs), hosted a public webinar in September 2024 to showcase the unique resources and capabilities available to investigators utilizing nonhuman primates in their research. Session presentations by the NPRC Directors and Associate Directors provided a comprehensive overview of the process for requesting animals and detailed the NPRCs’ criteria and procedures for prioritizing, reviewing, and allocating these resources. The webinar was recorded and posted to the ORIP website for future viewing by grantees and NIH staff.
- Training, Workforce Initiatives, and Community Engagement (TWICE) Team Meeting
ORIP staff were invited to present at the Training, Workforce Initiatives, and Community Engagement (TWICE) team meeting with the NIH Office of Data Science Strategy (ODSS) on September 19, 2024. ORIP and ODSS discussed the potential of co-funding S10 grants on computational resources, data science, and artificial intelligence, as well as other future collaborations.
- National Institute of Biomedical Imaging and Bioengineering Signs on to S10 Funding Opportunity
ORIP continues to strategically expand coalition building with more NIH institute and center (IC) partners to broaden its NIH-wide resource and infrastructure support. The National Institute of Biomedical Imaging and Bioengineering recently signed onto the S10 funding opportunity, catalyzed by DPCPSI leadership. These IC partnerships will contribute to the S10 program’s future success.
Read more in the archive.
