Positron emission tomography (PET) imagining with specific radioligands was used to follow cardiac innervation, inflammation and oxidative stress in an NHP model of cardiac sympathetic neurodegeneration. The radioligands may be useful biomarkers in detecting cardiac disease and evaluating new therapies for cardiac neurodegeneration and neuroprotection.
Strategic Plan Section
Developing Models of Human Diseases - Continue to develop and enhance human disease models and research-related resource programs to advance medical research