This paper reports improved drug load capacity of nanoparticles and their accumulation in tumors in vivo due to a new fabrication procedure. The ORIP-funded S10OD018505 photo-acoustic instrument and a PET imager were used to assess the therapeutic potential of these newly synthesized nanorods. Research grants from NCI and NIBIB supported the work reported here. Fifteen major users and their scientific collaborators have access to the instrument administered by the Medical Physics Department at the University of Wisconsin Madison.
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