Examinations of the brains of macaques after long-term ethanol self-administration demonstrated alterations in SNARE and SNARE-associated proteins in the basal amygdala, a brain region involved in aversive and reward-seeking behaviors. Sex differences were also observed. The authors propose that SNARE components may represent heritable phenotypes associated with ethanol drinking behavior.
Strategic Plan Section
Developing Models of Human Diseases - Continue to develop and enhance human disease models and research-related resource programs to advance medical research