- Machine Learning Leveraging Genomes from Metagenomes Identifies Influential Antibiotic Resistance Genes in the Infant Gut Microbiome
- Linking soil biology and chemistry in biological soil crust using isolate exometabolomics
- Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism
Three articles, published within the last two months, report discoveries enabled by an ORIP-funded sequencer (S10OD018174). The instrument placed in a core facility is used by many scientists; papers cited in these three papaers cumulatively credit 13 different investigators as co-authors, with research grants from six NIH Institutes and Centers. These papers address different scientific topics – genome-wide epigenomic alterations of fetal microglial genes; the integration of metabolite profiling, shotgun sequencing, and exometabolomics to study the structure of microbial communities; impact of formula feeding of premature infants on gut microbiome genes responsible for drug resistance – illustrating the breadth of science enabled by the shared instrument.