NPRC/Institute
Fred Hutchinson Cancer Research Center; University of Washington; HDT Bio; NIAID; Washington National Primate Research Center
Summary of Study
Findings suggest that the antibody response to SARS-CoV-2 in macaques shares many features with humans, but with substantial differences in the recognition of certain epitopes and considerable individual variability in antibody escape profiles, suggesting a diverse repertoire of antibodies that can respond to major epitopes in both humans and macaques.
Year Published
2022
References
PMID: 35404959 / doi: 10.1371/journal.ppat.1010155
Contact Info
Julie Overbaugh: joverbau@fredhutch.org
Keywords
SARS-CoV-2, phage-based deep mutational scanning, immune response, vaccination, primates
Coronavirus Investigated*
NHP Species
date entered
Study Type