Similarities between ZIKV infection of marmoset monkeys and humans include: asymptomatic in most cases, persistence of ZIKV in bodily fluids, and generation of neutralizing antibodies. Re-challenge of the monkeys with a Brazilian strain of ZIKV resulted in protection from re-infection. Results support use of this marmoset as a model for the human disease.
Strategic Plan Section
Developing Models of Human Diseases - Continue to develop and enhance human disease models and research-related resource programs to advance medical research