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Transplantation of ~750 million cryopreserved hESC – CMs enhanced cardiac function in macaques that had previously experienced a myocardial infarction. Grafts formed electromechanical junctions within the host heart and improved ventricular ejection volume. These data demonstrate the ability of stem cells to remuscularize the heart and improve ventricular function.

Strategic Plan Section
Developing Models of Human Diseases - Continue to develop and enhance human disease models and research-related resource programs to advance medical research