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ORIP Diversity Supplement Awards Helped a Young Investigator Advance His Career in Biomedical Research and Will Allow Him to Give Back to His Community

Dr. Corbin Schuster’s interest in biomedical research began during his undergraduate training, when he completed a 10-week internship at the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Maryland. According to Dr. Schuster, after that experience, “My interest in biomedical research—particularly in the study of microorganisms and infectious diseases—just grew.”

The WormGUIDES Atlas: A Window into the Mysteries of Neurodevelopment in Caenorhabditis elegans

More than 30 years after the adult nervous system and cell lineage of the roundworm Caenorhabditis elegans were first mapped,1 that map of neuron connectivity (i.e., the connectome) still enables scientists to better understand diverse neurobiological mechanisms. Today, C. elegans remains a widely used model for neuroscience research because of its short life cycle, transparent body, and homology to human genes expressed in neurodevelopment.

Animal Models and Resources for Coronavirus Research

ORIP aims to provide investigators with the resources and infrastructure they need to improve human health, including by supporting the development of animal models of human disease. The current coronavirus disease 2019 (COVID-19) pandemic in humans, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain, has compelled scientists around the world to work remarkably fast to develop vaccines and therapeutics using animal models.

Macaques, Humans, and Genomes: mGAP - A New Genetic Webtool To Discover Natural Occurring Diseases in Macaques

At the Oregon National Primate Research Center (ONPRC), a group of monkeys climb and swing across their large outdoor enclosure. At first glance, the small, fur-covered primates appear to bear little resemblance to their human handlers. Their DNA, however, tells a different story. The rhesus macaque (Macaca mulatta) shares about 93 percent of its genome with humans.1 For this reason, researchers study the rhesus macaque to understand primate evolution, comparative physiology, and the genetic basis of human diseases as well as addressing numerous scientific questions.

Micro-CT: A view into the structure of life for the analysis of tissue phenotypes

A convergence of scientific breakthroughs in chemistry, optics, and engineering in the early 1800s resulted in a miraculous new way to understand life—the light microscope. Microscopic studies of a wide range of samples by Johannes Müller and his protégés Matthias Schlieden, Theodor Schwann, and Rudolf Virchow resulted in a scientific epiphany and one of the most profound and useful revelations in history: Cells are the building blocks of all living organisms.

Training and Diversifying the Biomedical Workforce

Growing up, Dr. Raquel Salinas did not believe that someone like her could turn a passion for science into a career. It was the classes she encountered at the LBJ Science Academy, a magnet high school in Austin, Texas, that ultimately led her to a Bachelor of Science in Chemistry from the University of Texas at Austin. She then obtained a Master of Science in Biochemistry from Texas State University, and a Ph.D. in Pharmacology from Duke University. Dr.

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