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Washington National Primate Research Center (SPF Program)

Grant Number: U42OD011123

Research Emphasis/Objectives

The objective of this project is to maintain and enhance the specific-pathogen-free (SPF) pigtail macaque (Macaca nemestrina) breeding colony at the Washington National Primate Research Center (WaNPRC). M. nemestrina have unique immunological, genetic, behavioral, anatomical, and physiological characteristics that make them an essential model in a number of areas of research related to HIV/AIDS. Specific pathogens, including simian immunodeficiency virus, simian type D retrovirus, simian T-lymphotrophic virus 1, and Macacine alphaherpes virus 1 (McHV-1 or B virus), are a threat to animal or human health or interfere with research and must be excluded to optimize nonhuman primate research models. We maintain the WaNPRC SPF M. nemestrina breeding colony to provide animals of the highest quality to meet research needs. Genetic and diagnostic tools for this species have been developed for this species, ensuring that major histocompatibility complex (MHC)-typed, genetically defined, SPF M. nemestrina can be provided to meet HIV/AIDS researchers’ needs.

Services Provided

SPF pigtail macaques (M. nemestrina) are available for assignment to AIDS-related research projects. The WaNPRC Animal Allocation Committee has responsibility for allocating animal resources, with preference given to NIH-funded investigators. To request additional information regarding animal use fees and availability of pigtail macaques for a specific research project, please contact the Resource Contact listed below.

Contact Information

Washington National Primate Research Center
University of Washington Box 357330
Health Sciences Center, Room I-421
Seattle, WA 98195-7330
wanprc.org

Co-Principal Investigators

Charlotte E. Hotchkiss, D.V.M., M.S., Ph.D.
Phone: 206-685-2881
Fax: 206-616-1710
chotchki@uw.edu

Sally Thompson-Iritani, D.V.M., Ph.D.
Phone: 206-661-6294
Fax: 206-616-1710
sti2@uw.edu

Other/Resource Contacts

Jesse Day
Phone: 206-646-0154
jessed10@uw.edu