Washington National Primate Research Center

Grant Number: P51 OD010425

Research Emphasis/ObjectivesNon-human primate from WA NPRC

Empowering the delivery of leading-edge scientific discoveries to improve human health while promoting the highest standards of care, health, well-being, and conservation for primates around the world.

Current Research

The Washington National Primate Research Center (WaNPRC) is host to diverse units of scientific excellence, including Gene Therapy and Regenerative Medicine; Global Conservation, Education and Outreach; Infectious Disease and Translational Medicine; and Neuroscience. These units are refining new nonhuman primate (NHP) models of human disease. Our researchers are either developing effective vaccines and therapies for SARS-CoV-2, HIV/AIDS, and other infectious diseases, or they are advancing genetics, neuroscience, vision, or stem cell biology and therapy. Our Global Conservation, Education and Outreach unit is exploring the human–animal interface, conservation, and disease characterization in native communities throughout the world. The WaNPRC directly supports NIH’s mission to translate scientific advances into meaningful improvement in health care and medicine.

Services Provided

To Outside Investigators: The WaNPRC encourages the use of its resources by investigators from the national and international biomedical research communities. The WaNPRC is available for collaborative research initiatives involving center staff and outside investigators. In general, expenses are assumed by the initiating investigator, and collaborative research efforts are covered by grants acquired collaboratively.

Specimens: Banked serum, tissue, and DNA samples. Fresh blood, serum, plasma, tissues, and organs.

Animals: The WaNPRC maintains a colony of specific-pathogen-free pigtailed macaques (Macaca nemestrina) that are available for research projects. Additionally, housing capabilities are available for other macaque species and New World monkeys:

  • Pigtailed macaque (Macaca nemestrina)
  • Cynomolgus macaque (Macaca fascicularis)
  • Rhesus monkey (Macaca mulatta)
  • Squirrel monkey (Simia sciureus)

Veterinary Technical Services: Timed pregnancies, tether, radiography, sonography, endoscopy, experimental surgery, experimental diets, nursery, behavioral assessment.

Pathology and Diagnostic Services: Necropsies, clinical chemistry, hematology, histology, bacteriology, virology, parasitology.

Research Support: Project support and specimen collection.

Bioengineering: Electronic circuit and instrumentation support.

PET Imaging: PET imaging capabilities.

Mucosal Immunology and Virology: NHP blood and tissue processing and cryopreservation, immunophenotyping, intracellular staining and multicolor flow cytometry, complete blood count (CBC) and subset analyses, viral load quantification.

Systems Biology: Study design, RNA/DNA isolation, DNA-Seq and RNA-seq library construction, DNA and RNA sequencing, rRNA 16S sequencing (microbiome), ChiP-seq and 10 X Genomics single-cell RNA-seq.

Global Programs: Focusing on conservation biology, field study training, and international outreach activities. Areas of focus include NHP population status, genetic characterization, habitat viability, population management, disease risk, and sustainability modeling.

Contact Information

Washington National Primate Research Center
University of Washington Box 357330
Health Sciences Center, Room I-421
Seattle, WA 98195-7330
wanprc.uw.edu

Principal Investigator

Sean D. Sullivan, B.Sc.Pharm., M.Sc., Ph.D.
Professor and Dean
School of Pharmacy

Other/Resource Contacts

Michele A. Basso, Ph.D.
Director
Phone: 206-221-5718
Fax: 206-616-1710
mbasso@uw.edu

Deborah Fuller, Ph.D.
Associate Director, Research
Phone: 206-221-2328
fullerdh@uw.edu

Charlotte E. Hotchkiss, D.V.M., Ph.D., DACLAM
Associate Director, Animal Resources
Phone: 206-685-2881
chotchki@uw.edu

Tissue Distribution

Phone: 206-616-8122
necropsy@uw.edu

National Primate Research Centers

Last updated: 04-20-2022