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Funding Opportunities List

ORIP awards grants to support research-related resources and infrastructure, including animal models for human diseases, cutting-edge scientific instrumentation, construction and modernization of research facilities, and research training opportunities for veterinary scientists. Use the fields below or scroll down to explore open funding opportunities supported by ORIP. The table headers can be selected to sort the data alphabetically or chronologically. The Divisions in the last column refer to ORIP’s Division of Comparative Medicine (DCM), Division of Construction and Instruments (DCI), and Small Business (SB). If you have questions about the funding opportunities listed below, please contact ORIPoutreach@mail.nih.gov.

Title Funding Number Sort descending Organization Funding Mechanism Description Expiration Date Division Research Contact
Notice of Special Interest (NOSI): Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Model... NOT-OD-22-039 ORIP R21 05/08/2024 DCM See Inquiries
Notice of Special Interest (NOSI): Revision Applications to add a Curation and Informatics Component to existing Animal and Biological Material Resour... NOT-OD-23-068 ORIP P40 01/08/2026 DCM See Inquiries
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (... NOT-OD-23-170 ORWH Admin Supp 10/09/2026 See Inquiries
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 NIH R01 01/08/2025 DCM Agency Contacts
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) PA-20-188 NIH K99/R00 05/08/2024 DCM Agency Contacts
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) PA-20-190 NIH K01 05/08/2024 DCM Agency Contacts
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 OD Admin Supp 09/10/2024 Agency Contacts
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) PA-23-048 NIH T32 05/08/2026 DCM Agency Contacts
Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35) PA-23-080 NIH T35 05/08/2026 DCM Agency Contacts
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed) PA-23-189 OD Admin Supp 05/08/2026 Agency Contacts
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) PA-24-141 NIH R13 01/08/2027 DCM Agency Contacts
Early Stage Investigator Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) PAR-21-109 NIA R21 05/08/2024 DCM Agency Contacts
Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed) PAR-21-167 ORIP R21 05/08/2024 DCM Agency Contacts
Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R43/R44 Clinical Trial Not Allowed) PAR-21-225 ORIP R43/R44 09/06/2024 SB Agency Contacts
Novel Tools and Devices for Animal Research Facilities and to Support Care of Animal Models (R41/R42 Clinical Trial Not Allowed) PAR-21-226 ORIP R41/R42 09/06/2024 SB Agency Contacts
Screening and Functional Validation of Human Birth Defects Genomic Variants (R01 Clinical Trial Not Allowed) PAR-21-229 NICHD R01 05/08/2025 DCM Agency Contacts
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) PAR-22-060 NIDCR R15 01/08/2025 DCM Agency Contacts
High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) PAR-22-079 ORIP S10 06/04/2024 DCI Agency Contacts
Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) PAR-22-080 ORIP S10 06/04/2024 DCI Agency Contacts
Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed) PAR-22-081 ORIP S10 06/04/2024 DCI Agency Contacts
Development of Animal Models and Related Materials for HIV/AIDS Research (R24 Clinical Trials Not Allowed) PAR-22-204 ORIP R24 01/08/2025 DCM Agency Contacts
Development of Animal Models and Related Biological Materials for Down Syndrome Research (R24 Clinical Trials Not-Allowed) PAR-22-247 OD R24 05/26/2025 DCM Agency Contacts
Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R24 Clini... PAR-23-039 ORIP R24 05/26/2025 DCM Agency Contacts
Development of Resources and Technologies for Enhancing Rigor, Reproducibility, and Translatability of Animal Models in Biomedical Research (R01) PAR-23-040 ORIP R01 07/06/2025 DCM Agency Contacts
Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trials Not Allowed) PAR-23-067 OD R21 01/08/2026 DCM Agency Contacts
Mentored Career Development Program for Early Stage Investigators Using Nonhuman Primate Research Models (K01 Independent Clinical Trial Not Allowed) PAR-23-073 NIAID K01 01/08/2026 DCM Agency Contacts
Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed) PAR-23-126 ORIP P51 05/26/2026 DCM Agency Contacts
Limited Competition: Small Grant Program for ORIP Special Emphasis Research Career Award (SERCA) K01 Recipients (R03 Clinical Trials Not Allowed) PAR-23-127 ORIP R03 05/08/2026 DCM Agency Contacts
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 NIGMS S10 06/03/2025 DCI Agency Contacts
Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) PAR-23-215 ORIP R21 09/08/2025 DCM Agency Contacts
HIV/AIDS Scholars Using Nonhuman Primate (NHP) Models Program (K01 Independent Clinical Trial Not Allowed) PAR-23-225 ORIP K01 09/08/2025 DCM Agency Contacts
Limited Competition: Development and Renovation of Facilities for Expanding the Breeding Capacity of Specific Pathogen Free Non-Human Primates to Supp... PAR-24-033 ORIP C06 01/08/2025 DCI Agency Contacts
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) PAR-24-075 OD R01 12/29/2026 DCM Agency Contacts
Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed) PAR-24-078 ORIP U42 01/08/2027 DCM Agency Contacts
Limited Competition: Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed) PAR-24-105 ORIP U42 09/02/2024 DCM Agency Contacts
Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed) PAR-24-129 ORIP U42 01/08/2027 DCM Agency Contacts
Utilizing Equipment to Study Environmental Extrinsic Factors and Enhance Rigor and Reproducibility of Animal Research (R24, Clinical Trials Not-Allowe... PAR-24-167 ORIP R24 09/26/2026 DCM Agency Contacts
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed) RFA-NS-23-006 NINDS R43/R44 04/05/2025 SB Agency Contacts
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed) RFA-NS-23-007 NINDS R41/R42 04/05/2025 SB Agency Contacts
INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21... RFA-OD-21-007 OD R21 07/04/2024 DCM Agency Contacts
Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 ... RFA-OD-22-009 OD R01 07/02/2024 DCM Agency Contacts
Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed) RFA-OD-22-013 ORIP R24 05/26/2025 DCM Agency Contacts
Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed) RFA-OD-23-001 ORIP P40 01/08/2026 DCM Agency Contacts