Katarzyna Kent,Kaori Nozawa,Rachel Parkes,Laura Dean,Frey Daniel,Mei Leng,Antrix Jain,Anna…
Large-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction
Proceedings of the National Academy of Sciences of the United States of America
2024-12-12
Imran S Khan,Christopher Molina,Xin Ren,Vincent C Auyeung,Max Cohen,Tatsuya Tsukui,Amha Atakilit…
Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification
eLife
2024-12-11
Johnathan V Le,Jason K Mendes,Konstantinos Sideris,Erik Bieging,Spencer Carter,Josef Stehlik,Edward…
Free-Breathing Ungated Radial Simultaneous Multi-Slice Cardiac T1 Mapping
Journal of magnetic resonance imaging : JMRI
2024-12-11
Amy D Hanna,Ting Chang,Kevin S Ho,Rachel Sue Zhen Yee,William Cameron Walker,Nadia Agha,Chih-Wei…
Mechanisms underlying dilated cardiomyopathy associated with FKBP12 deficiency
The Journal of general physiology
2024-12-11
Somen K Mistri,Brianna M Hilton,Katherine J Horrigan,Emma S Andretta,Remi Savard,Oliver Dienz…
SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire
eLife
2024-12-10
Peng Liu,Yuchen Pan,Hung-Ching Chang,Wenjia Wang,Yusi Fang,Xiangning Xue,Jian Zou,Jessica M…
Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating
Briefings in bioinformatics
2024-12-10
Maryse Lapierre-Landry,Eric Y Lu,Matthew T McPheeters,Made Airanthi K Widjaja-Adhi,David L Wilson…
Quantifying the Corneal Nerve Whorl Pattern
Translational vision science & technology
2024-12-10
Chase M Carver,Sonia L Rodriguez,Elizabeth J Atkinson,Andrew J Dosch,Niels C Asmussen,Paul T Gomez…
IL-23R is a senescence-linked circulating and tissue biomarker of aging
Nature aging
2024-12-10
Tom Earnest,Braden Yang,Deydeep Kothapalli,Aristeidis Sotiras,Alzheimer’s Disease Neuroimaging…
Comprehensive evaluation of AT(N) imaging biomarkers for predicting cognition
medRxiv : the preprint server for health sciences
2024-12-09
Rebecca Signer,Carina Seah,Hannah Young,Kayla Retallick-Townsley,Agathe de Pins,Alanna Cote,Seoyeon…
BMI Interacts with the Genome to Regulate Gene Expression Globally, with Emphasis in the Brain and Gut
medRxiv : the preprint server for health sciences
2024-12-09
Mitchell L Kim-Fu,Ansel R Moll,Esteban E Hernandez,Boris Droz,Thierry N J Fouquet,Jennifer Field
Correction: Fluorinated aromatic PCBTF and 6:2 diPAP in bridge and traffic paints
Environmental science. Processes & impacts
2024-12-09
Katharina Ronacher,Léanie Kleynhans,Carine Kunsevi-Kilola,Happy Tshivhula,Tariq Webber,Alana Keyser…
Human Alveolar Macrophage Function is Impaired in Tuberculosis Contacts With Diabetes
Research square
2024-12-09
Jiahao Li,Pablo Villar-Calle,Caitlin Chiu,Mahniz Reza,Nupoor Narula,Chao Li,Jinwei Zhang,Thanh D…
Spiral cardiac quantitative susceptibility mapping for differential cardiac chamber oxygenation-Initial validation in relation to invasive blood sampling
Magnetic resonance in medicine
2024-12-06
Merissa N Morey,Christine M Montone,Michael R Dworzak,Glenn P A Yap,Eric D Bloch
Tunable synthesis of heteroleptic zirconium-based porous coordination cages
Chemical science
2024-12-06
Monica Ardon,Lily Nguyen,Rui Chen,Jeffrey Rogers,Tim Stout,Sara Thomasy,Ala Moshiri
Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder
Investigative ophthalmology & visual science
2024-12-06
Cameron J Kaminsky,Jericha Mill,Thomas Raife,Lingjun Li
Quantitative Endogenous Polyamine Analysis via Capillary Electrophoresis/Mass Spectrometry: Characterization and Practical Considerations
Electrophoresis
2024-12-06
Sandra Vergara,Xiaohong Zhou,Ulises Santiago,Mounia Alaoui-El-Azher,James F Conway,Nicolas Sluis…
Structural basis of deoxynucleotide addition by HIV-1 RT during reverse transcription
Nature communications
2024-12-05
David Izquierdo-Garcia,Pauline Désogère,Anne L Philip,David E Sosnovik,Ciprian Catana,Peter Caravan
First-in-human Evaluation of Safety and Dosimetry of [64 Cu]FBP8: A fibrin-binding PET Probe
Molecular imaging and biology
2024-12-05
Anna C Winnicki,Melanie H Dietrich,Lee M Yeoh,Lenore L Carias,Wanlapa Roobsoong,Chiara L Drago…
Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages
Nature communications
2024-12-05
Kota Ishibashi,Yuichi Shichino,Peixun Han,Kimi Wakabayashi,Mari Mito,Toshifumi Inada,Seisuke Kimura…
Translation of zinc finger domains induces ribosome collision and Znf598-dependent mRNA decay in zebrafish
PLoS biology
2024-12-05
Wan-Chun Su,John Mutersbaugh,Wei-Lun Huang,Anjana Bhat,Amir Gandjbakhche
Using deep learning to classify developmental differences in reaching and placing movements in children with and without autism spectrum disorder
Scientific reports
2024-12-05
Zeinab M Chahine,Mohit Gupta,Todd Lenz,Thomas Hollin,Steven Abel,Charles Banks,Anita Saraf,Jacques…
PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum
eLife
2024-12-05
Kevin N Eckstein,Daniel Yoon,Margrethe Ruding,Ramin Balouchzadeh,Aaliyah Thompson-Mazzeo,Ruth J…
Mechanically anisotropic phantoms for magnetic resonance elastography
Magnetic resonance in medicine
2024-12-04
Adriana Coricello,Alanya J Nardone,Antonio Lupia,Carmen Gratteri,Matthijn Vos,Vincent Chaptal…
3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase
Nature communications
2024-12-03
Maxim Oleynikov,Samie R Jaffrey
RNA tertiary structure and conformational dynamics revealed by BASH MaP
eLife
2024-12-03
Celine A Manigbas,Bharati Jadhav,Paras Garg,Mariya Shadrina,William Lee,Gabrielle Altman,Alejandro…
A phenome-wide association study of tandem repeat variation in 168,554 individuals from the UK Biobank
Nature communications
2024-12-03
Christopher J Presloid,Jialiu Jiang,Pratistha Kandel,Henry R Anderson,Patrick C Beardslee,Thomas M…
ClpS Directs Degradation of N-Degron Substrates With Primary Destabilizing Residues in Mycolicibacterium smegmatis
Molecular microbiology
2024-12-03
Xitong Chen,Stephanie C Leach,Juniper Hollis,Dillan Cellier,Kai Hwang
The thalamus encodes and updates context representations during hierarchical cognitive control
PLoS biology
2024-12-02
Jacqueline M Griswold,Mayte Bonilla-Quintana,Renee Pepper,Christopher T Lee,Sumana Raychaudhuri…
Membrane mechanics dictate axonal pearls-on-a-string morphology and function
Nature neuroscience
2024-12-02
Christina Rabeler,Nicholas Paterna,Rajiv Potluri,Lia R D'Alessandro,Anusha Bhatia,Shu Yi Chen…
Locus-specific differential expression of human satellite sequences in the nuclei of cancer cells and heat-shocked cells
Nucleus (Austin, Tex.)
2024-12-02
Panga J Reddy,Zhi Sun,Helisa H Wippel,David H Baxter,Kristian Swearingen,David D Shteynberg,Mukul K…
Borrelia PeptideAtlas: A proteome resource of common Borrelia burgdorferi isolates for Lyme research
Scientific data
2024-12-02
Renata Mazurek,Serena Tharakan,Spyros A Mavropoulos,Deanndria T Singleton,Olympia Bikou,Tomoki…
AAV delivery strategy with mechanical support for safe and efficacious cardiac gene transfer in swine
Nature communications
2024-12-01
Anna L McDonald,Andrew M Boddicker,Marina I Savenkova,Ian M Brabb,Xiaodong Qi,Daniela D Moré…
Efficient small fragment sequencing of human, cattle, and bison miRNA, small RNA, or csRNA-seq libraries using AVITI
BMC genomics
2024-11-29
Daniel B Hoffman,Albino G Schifino,Marion A Cooley,Roger X Zhong,Junwon Heo,Courtney M Morris…
Low intensity, high frequency vibration training to improve musculoskeletal function in a mouse model of volumetric muscle loss
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2024-11-29
Maxime Zamba-Campero,Daniel Soliman,Huaxin Yu,Amanda G Lasseter,Yuen-Yan Chang,Julia L Silberman…
Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice
Nature communications
2024-11-29
Frederick A Bagdasarian,Kristian Larsen,Hong Ping Deng,Patrick M Fisher,Joseph B Mandeville…
Neurochemical characterization of 5-HT2A R partial agonists with simultaneous PET-MRI
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
2024-11-29
Chris Jennings-Shaffer,David H Rich,Matthew Macaulay,Michael D Karcher,Tanvi Ganapathy,Shosuke…
Finding high posterior density phylogenies by systematically extending a directed acyclic graph
ArXiv
2024-11-28
Chunxiang Zhang,Hua Ma,Daniel DeRoche,Eric M Gale,Pamela Pantazopoulos,Nicholas J Rotile,Himashinie…
Manganese-based type I collagen-targeting MRI probe for in vivo imaging of liver fibrosis
Research square
2024-11-28
Dahyana Arias Escayola,Chuyue Zhang,Emily Nischwitz,Leonard Schärfen,Kerstin Dörner,Korinna Straube…
Identification of coilin interactors reveals coordinated control of Cajal body number and structure
The Journal of cell biology
2024-11-27
Aruesha Srivastava,Aryana Nair,Omolara C O Dawson,Raymond Gao,Lijun Liu,Justin K Craig,Kevin P…
Structures of Trichomonas vaginalis macrophage migratory inhibitory factor
Acta crystallographica. Section F, Structural biology communications
2024-11-27
Aaron M Fleming,Justin C Dingman,Cynthia J Burrows
CO2 protects cells from iron-Fenton oxidative DNA damage in Escherichia coli and humans
Proceedings of the National Academy of Sciences of the United States of America
2024-11-27
Elias Tanuhadi,Anna S Bair,Mary Johnson,Philip Fontaine,Jerzy Klosin,Sudipta Pal,Polly L Arnold
Stabilization of reactive rare earth alkyl complexes through mechanistic studies
Chemical science
2024-11-27
Ho Yee Joyce Fung,Jenny Jiou,Ashley B Niesman,Natalia E Bernardes,Yuh Min Chook
Nap1 and Kap114 co-chaperone H2A-H2B and facilitate targeted histone release in the nucleus
The Journal of cell biology
2024-11-27
Marzieh Salimi,Shreyas Kuddannaya,Jeff W M Bulte
Pharmacokinetic Profiling of Unlabeled Magnetic Nanoparticles Using Magnetic Particle Imaging as a Novel Cold Tracer Assay
Nano letters
2024-11-26
Grigor Varuzhanyan,Chia-Chun Chen,Jack Freeland,Tian He,Wendy Tran,Kai Song,Liang Wang,Donghui…
PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity
Proceedings of the National Academy of Sciences of the United States of America
2024-11-26
Sanghoon Lee,Youngbin Cho,Yiting Li,Ruxuan Li,Angela Wong Lau,Matthew S Laird,Daniel Brown…
Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer
Oncoimmunology
2024-11-26
Debamalya Chatterjee,Ziru Zhang,Pei-Yu Lin,Po-Hao Wang,Gurpreet K Sidhu,Neela H Yennawar,Jo-Wei…
Maize unstable factor for orange1 encodes a nuclear protein that affects redox accumulation during kernel development
The Plant cell
2024-11-26
John H Day,Catherine M Della Santina,Pema Maretich,Alexander L Auld,Kirsten K Schnieder,Tay Shin…
High-throughput expansion microscopy enables scalable super-resolution imaging
eLife
2024-11-26
Junli Wang,Kunpeng Chen,Bosen Jin,Wonsik Woo,Michael Lum,Alexa Canchola,Yiwen Zhu,Yujie Men,Jinyong…
Pyrolysis of Two Perfluoroalkanesulfonates (PFSAs) and PFSA-Laden Granular Activated Carbon (GAC): Decomposition Mechanisms and the Role of GAC
Environmental science & technology
2024-11-26
Rishav Mitra,Emery T Usher,Selin Dedeoğlu,Matthew J Crotteau,Olivia A Fraser,Neela H Yennawar,Varun…
Molecular insights into the interaction between a disordered protein and a folded RNA
Proceedings of the National Academy of Sciences of the United States of America
2024-11-26
Young Chul Kim,Vivek Das,Sadhana Kanoo,Huazhen Yao,Stephanie M Stanford,Nunzio Bottini,Anil…
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition or GLP1 receptor agonism
American journal of physiology. Renal physiology
2024-11-26
August J Rothenberger,Harrison M Bergman,He Li,Miao Qi,Yunfei Wang,Yi Liu,T Don Tilley
Direct ladderization of cyclooctatetraene-containing, processable conjugated ladder polymers from annulated bis-zirconacyclopentadienes
Chemical science
2024-11-25
Andrea O'Malley,Joshua M Ray,Patrycja Kitlas,Thimo Ruethers,A Brenda Kapingidza,Tomasz Cierpicki…
Comparative studies of seafood and reptile α- and β-parvalbumins
Protein science : a publication of the Protein Society
2024-11-25
Zicong Wang,Jingwei Zhang,Lingjun Li
Recent Advances in Labeling-Based Quantitative Glycomics: From High-Throughput Quantification to Structural Elucidation
Proteomics
2024-11-24
Fabio Stossi,Pankaj K Singh,Michela Marini,Kazem Safari,Adam T Szafran,Alejandra Rivera Tostado…
SPACe: an open-source, single-cell analysis of Cell Painting data
Nature communications
2024-11-23
Prashant N M,John F Fullard,Tereza Clarence,Deepika Mathur,Clara Casey,Evelyn Hennigan,Marcela…
A multi-region single nucleus transcriptomic atlas of Parkinson's disease
Scientific data
2024-11-23