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TMEM65 functions as the mitochondrial Na+ /Ca2+ exchanger
Nature cell biology
2025-07-21
Jaigeeth Deveryshetty,Ayush Mistry,Sushil Pangeni,Mohamed Ghoneim,Monica Tokmina-Lukaszewska,Steven…
Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination
Nature communications
2025-07-21
Rachel R Chan,Kaitlin M Landy,Kyle J Gibson,Sachin P Kulkarni,Junjing Deng,Byeongdu Lee,Joseph…
Programming Defects and Cavities into Colloidal Crystals Engineered With DNA
Advanced materials (Deerfield Beach, Fla.)
2025-07-21
Daniel J Nilson,Beate Schwer,Steven C Almo,Stewart Shuman,Agnidipta Ghosh
Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic sinefungin
Nucleic acids research
2025-07-19
Hanne Laakso,Lin Wu,Sara Ponticorvo,Raimo A Salo,Jaakko Paasonen,Ekaterina Paasonen,Mikko Kettunen…
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Magnetic resonance in medicine
2025-07-17
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Targeted CRISPR approach reveals an essential role for neuropeptide Y receptor Y5 in Ewing sarcoma extrapulmonary metastasis
Oncogene
2025-07-17
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Nucleic acids research
2025-07-17
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Nature communications
2025-07-17
Jose M Adrover,Xiao Han,Lijuan Sun,Takeo Fujii,Nicole Sivetz,Juliane Daßler-Plenker,Clary Evans…
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Nature
2025-07-16
David J Arpin,S H Subramony,READISCA Consortium,David E Vaillancourt,Tetsuo Ashizawa,Alexandra Durr…
Fixel-Based Analysis of Diffusion Imaging as a Quantitative Marker of Disease State in Spinocerebellar Ataxia
Annals of clinical and translational neurology
2025-07-16
Ya'el Courtney,Maria K Lehtinen
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2025-07-16
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Clinical & experimental metastasis
2025-07-15
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eLife
2025-07-15
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JCI insight
2025-07-15
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The Journal of clinical investigation
2025-07-15
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Nature communications
2025-07-14
Logan J Fickling,Aaron P Cook,Wenxin Wu,Angel Erbey Ibarra,Lingjun Li,Michael P Nusbaum
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Journal of neurophysiology
2025-07-14
Victoria S Halls,Larry L David,Keith D Zientek,Kirsten J Lampi
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Chembiochem : a European journal of chemical biology
2025-07-14
Joenisse M Rosado-Rosa,Dharmeshkumar Parmar,Stanislav S Rubakhin,Joshua D Shrout,Jonathan V Sweedler
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Scientific reports
2025-07-13
Corey Fehlberg,Danny John,Brian Kang,James S Choi,Susana Cerqueira,Alexis Brake,Jae K Lee
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2025-07-13
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Multivariate Framework of Metabolism in Advanced Prostate Cancer Using Whole Abdominal and Pelvic Hyperpolarized 13 C MRI-A Correlative Study with Clinical Outcomes
Cancers
2025-07-12
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Dysregulation of Arachidonic Acid Metabolism Drives Inflammatory Lipid Production in Localized Provoked Vulvodynia
Nutrients
2025-07-12
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Nature communications
2025-07-11
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Molecular cell
2025-07-11
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Nature cell biology
2025-07-11
Tian Liang,Charles E Smith,Yuanyuan Hu,Hong Zhang,Chuhua Zhang,James P Simmer,Jan C-C Hu
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Scientific reports
2025-07-10
Catherine M Phelps,Nathaniel B Willis,Tingting Duan,Amanda H Lee,Yue Zhang,Daphne M Rodriguez J…
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Cell
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Nature communications
2025-07-10
Van K Ninh,Melissa Barlow,Sidar Aydin,Cameron Servetus Brand,Justin Yu,Jeffrey Smith,Jamie…
Cardiomyocyte YAP represses myocardial inflammation and fibrosis and restrains MEF2 regulated gene expression
American journal of physiology. Heart and circulatory physiology
2025-07-10
Chaylen Andolino,Eylem Kulkoyluoglu Cotul,Zilin Xianyu,Yun Li,Divya Bhat,Mitchell Ayers,Kimberly K…
Fatty acid synthase-derived lipid stores support breast cancer metastasis
Cancer & metabolism
2025-07-10
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Nature communications
2025-07-10
Zoe A Figueroa,Jose L Martin,Arzu Ulu,William Agnew-Svoboda,Teresa Ubina,Martin M Riccomagno,Todd A…
Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Glia
2025-07-10
Ed Zandro M Taroc,Enrico Amato,Alexis M Semon,Nikki Dolphin,Briane Beck,Sophie Belin,Yannick…
Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH-1 Migration
Glia
2025-07-09
Claudia Jakubzick,Soubhik Ghosh,Xin Li,Kavita Rawat,Aishwarya Dighal,Stephanie Kalinowski,Fred…
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2025-07-09
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Nature communications
2025-07-08
Jiayu Zhang,Elizabeth C Chavez,Melina Winkler,Jianche Liu,Sebastian Carver,Aaron E Lin,Abhishek…
Amino acid changes in two viral proteins drive attenuation of the yellow fever 17D vaccine
Nature microbiology
2025-07-08
Ainsley Temudo,Nina Dolfen,Bradley R King,Genevieve Albouy
The human medial temporal lobe represents memory items in their ordinal position in both declarative and motor memory domains
PLoS biology
2025-07-07
Ahmed Abdelgawad,Yiyao Huang,Olesia Gololobova,Yanbao Yu,Kenneth W Witwer,Vijay Parashar,Mona Batish
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Journal of extracellular vesicles
2025-07-07
Joshua J Milligan,Rachel L Strader,Arunangshu Chakrabarty,Max Ney,Parul Sirohi,Jonathan C Su…
Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2025-07-06
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Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype
Nature communications
2025-07-04
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Soft Extrudable Dendritic Particles with Nanostructured Tendrils for Local Adhesion and Drug Release to Bladder Cancers
Advanced materials (Deerfield Beach, Fla.)
2025-07-04
Anna M Kolarzyk,Yujin Kwon,Elizabeth Oh,Keng-Jung Lee,Su-Yeon Cho,Issahy Cano,Renhao Lu,Tae Joon…
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Molecular cancer
2025-07-04
Jennifer Erin Dawson,Iris Nira Smith,Ann Marie Tushar,Charis Eng
Elucidating PTEN conformational dynamics and phosphatase regulation via integrative modeling and mutation prediction
Structure (London, England : 1993)
2025-07-04
Valerie J Sydnor,Joëlle Bagautdinova,Bart Larsen,Michael J Arcaro,Deanna M Barch,Dani S Bassett…
Human thalamocortical structural connectivity develops in line with a hierarchical axis of cortical plasticity
Nature neuroscience
2025-07-04
Naresh T Deoli,Christian Siebenwirth,Andrew D Harken,Brian Ponnaiya,Yuewen Tan,Gerhard Randers…
Integration of an electron beam ion trap source into an electrostatic accelerator for pre-clinical cancer research
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment
2025-07-04
Jea Woo Kang,Lora A Khatib,Margo B Heston,Amanda H Dilmore,Jennifer S Labus,Yuetiva Deming,Leyla…
Gut microbiome compositional and functional features associate with Alzheimer's disease pathology
Alzheimer's & dementia : the journal of the Alzheimer's Association
2025-07-03
Sung Eun Wang,Yubao Cheng,Jaechul Lim,Mi-Ae Jang,Emily N Forrest,Yuna Kim,Meaghan Donahue,Sungsin…
Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome
Nature communications
2025-07-03
Grace Bower,Ethan W Hollingsworth,Sandra H Jacinto,Joshua A Alcantara,Benjamin Clock,Kaitlyn Cao…
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Nature
2025-07-03
Katie A Matatall,Trisha K Wathan,Minh Nguyen,Hu Chen,Alexandra McDonald,Guantong Qi,Julia A Belk…
TET2-mutant myeloid cells mitigate Alzheimer's disease progression via CNS infiltration and enhanced phagocytosis in mice
Cell stem cell
2025-07-03
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ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets
Nature communications
2025-07-02
Bradley P Clarke,Shengyan Gao,Menghan Mei,Dongqi Xie,Alexia E Angelos,Ashley Vazhavilla,Pate S Hill…
Structural mechanism of DDX39B regulation by human TREX-2 and a related complex in mRNP remodeling
Nature communications
2025-07-02
Huiwang Zhan,Dhiman Sankar Pal,Jane Borleis,Yu Deng,Yu Long,Chris Janetopoulos,Chuan-Hsiang Huang…
Self-organizing glycolytic waves tune cellular metabolic states and fuel cancer progression
Nature communications
2025-07-02
Koto Kon-Nanjo,Tetsuo Kon,Tracy Chih-Ting Koubkova Yu,Diego Rodriguez-Terrones,Francisco Falcon…
The dynamic genomes of Hydra and the anciently active repeat complement of animal chromosomes
Genome biology
2025-07-02
Curtis W Boswell,Caroline Hoppe,Alice Sherrard,Liyun Miao,Mina L Kojima,Pieter Martino,Ning Zhao…
Genetically encoded affinity reagents are a toolkit for visualizing and manipulating endogenous protein function in vivo
Nature communications
2025-07-02
Aliyah Habashy,Christopher Acree,Keun-Young Kim,Ali Zahraei,Martin Dufresne,Sebastien Phan,Melanie…
Spatial patterns of hepatocyte glucose flux revealed by stable isotope tracing and multi-scale microscopy
Nature communications
2025-07-02
Chanhee Park,Taekyung Ryu,Rashida Mohamed-Hinds,Kyungdo Kim,Jin Hyeok Kim,Lin Zou,Brittney Williams…
Proteomic profiling of plasma extracellular vesicles identifies signatures of innate immunity, coagulation, and endothelial activation in septic patients
Scientific reports
2025-07-02
Ekaterina Korotkevich,Daniel N Conrad,Zev J Gartner,Patrick H O'Farrell
Selfish mutations promote age-associated erosion of mtDNA integrity in mammals
Nature communications
2025-07-02
Nuo Sun,Hayley Barta,Samhita Chaudhuri,Kangxuan Chen,Jiacheng Jin,Hongke Luo,Mingchong Yang,Judith…
Mitophagy mitigates mitochondrial fatty acid β-oxidation deficient cardiomyopathy
Nature communications
2025-07-02
Anita Kaw,Suravi Majumder,Jose E Esparza Pinelo,Ting Wu,Zbigniew Starosolski,Zhen Zhou,Albert J…
Immature Acta2R179C/+ smooth muscle cells cause moyamoya-like cerebrovascular lesions in mice prevented by boosting OXPHOS
Nature communications
2025-07-02
Tyler Blazey,John J Lee,Abraham Z Snyder,Manu S Goyal,Tamara Hershey,Ana Maria Arbeláez,Marcus E…
Hyperglycemia selectively increases cerebral non-oxidative glucose consumption without affecting blood flow
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
2025-07-01
Elwin D Clutter,Wending Yang,Jacob Han,Nihal Kaplan,Han Peng
Inhibitor of DNA-Binding 3 Is a Novel Regulator of Limbal Epithelial Cell Migration Via the EphA2/Akt Signaling Pathway
Investigative ophthalmology & visual science
2025-07-01
Jeffrey Koury,Hina Singh,Samantha N Sutley-Koury,Dominic Fok,Xinru Qiu,Ricky Maung,Benjamin B…
EphB2-mediated ephrin-B reverse signaling on microglia drives an anti-viral, but inflammatory and neurotoxic response associated with HIV
Journal of neuroinflammation
2025-06-30
James Widner,Phyllis L Faust,Elan D Louis,Hirofumi Fujita
Axonal pathology differentially affects human Purkinje cell subpopulations in the essential tremor cerebellum
Proceedings of the National Academy of Sciences of the United States of America
2025-06-30
Sota Akiyama,Rohini S Ople,Alexander Kremsmair,Nokomis Ramos-Gonzalez,Thomas Nedungadan,Brandon J…
Total synthesis and biological activity of "carbamorphine": O-to-CH2 replacement in the E-ring of the morphine core structure
Proceedings of the National Academy of Sciences of the United States of America
2025-06-30
Brittany Percin,Jared L Zitnay,Robert Z Tashjian,Gilles Walch,Peter N Chalmers,Christopher D Joyce…
Accuracy of implant placement after pre-operative planning using Blueprint Software in inlay and onlay reverse total shoulder arthroplasty systems: A cadaver study
Journal of shoulder and elbow surgery
2025-06-28
Mariann Guzman-Espinoza,Helen M Vander Wende,Jessica L Pacheco,Alejandra Olano Roldán,Erica J…
Characterization of Pumilio gene expression during early neural crest development
Differentiation; research in biological diversity
2025-06-28
Enrico Amato,Alexis M Semon,Paolo E Forni
Tracing Early Migratory Neurons in the Developing Nose Using Contactin-2 (Cntn2) CreERT2
Genesis (New York, N.Y. : 2000)
2025-06-28
Shan Jiang,Zhaoqian Su,Nathaniel Bloodworth,Yunchao Liu,Cristina E Martina,David G Harrison,Jens…
Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA-A0201
PloS one
2025-06-27
Michael G Stewart,Joseph S Carrier,Jacob A Zahm,Stephen C Harrison,Matthew P Miller
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores
The Journal of cell biology
2025-06-27
Si Tong Bao,Yongseok Hong,Haoyu Jiang,Luke T Lackovic,Shayan Louie,Ding Xu,Fay Ng,Nicholas Olsen…
Chirality Unbound in Graphene Nanoribbons
Angewandte Chemie (International ed. in English)
2025-06-27
Aaron S Birchfield,Faik N Musayev,Abdul J Castillo,George Zorn,Brian Fuglestad
Broad PFAS Binding with Fatty Acid Binding Protein 4 Is Enabled by Variable Binding Modes
JACS Au
2025-06-27
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Nutritionally Responsive PMv DAT Neurons Are Dynamically Regulated During Pubertal Transition
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2025-06-27
Hui Xiao,Jessica Shiu,Chi-Fen Chen,Jie Wu,Peijie Zhou,Sahil S Telang,Rolando Ruiz-Vega,Robert A…
Uncovering minimal pathways in melanoma initiation
Nature communications
2025-06-26
Melissa R Lyman,Jacob T Mitchell,Sidharth Raghavan,Luciane T Kagohara,Amanda L Huff,Saurav D Haldar…
Spatial Proteomics and Transcriptomics Reveal Early Immune Cell Organization in Pancreatic Intraepithelial Neoplasia
JCI insight
2025-06-26
Wesley Huang,Yuezhong Zhang,Nupur K Das,Sumeet Solanki,Chesta Jain,Marwa O El-Derany,Imhoi Koo…
Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD
Nature metabolism
2025-06-26
Adam J Paulsen,Ira Driscoll,Brianne M Breidenbach,Matthew Glittenberg,Sarah R Lose,Yue Ma,Mark A…
The impact of estimated cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline
Alzheimer's & dementia (New York, N. Y.)
2025-06-26
Maria Koromina,Ashvin Ravi,Georgia Panagiotaropoulou,Brian M Schilder,Jack Humphrey,Alice Braun,Tim…
Fine-mapping genomic loci refines bipolar disorder risk genes
Nature neuroscience
2025-06-25
Anindhya S Das,Charles P Rabolli,Colton R Martens,Han-Kai Jiang,Yingshen Zhang,Aubree A Zimmer…
AIMP3 maintains cardiac homeostasis by regulating the editing activity of methionyl-tRNA synthetase
Nature cardiovascular research
2025-06-25
Can B Uzundal,Qixin Feng,Weichen Tang,Chen Hu,Collin Sanborn,Yoseob Yoon,Sudi Chen,Jiawei Ruan…
Efficient on-chip terahertz generation and detection with GaN photoconductive emitters
Light, science & applications
2025-06-25
Ruixu Huang,Caroline E Kratka,Jeffrey Pea,Cai McCann,Jack Nelson,John P Bryan,Luhan T Zhou,Daniela…
Single-cell and spatiotemporal profile of ovulation in the mouse ovary
PLoS biology
2025-06-24
Nicholas A Wood,Alyssa Kraft,Kyungsoo Shin,Tata Gopinath,Francesca M Marassi
In situ NMR reveals a pH sensor motif in an outer membrane protein that drives bacterial vesicle production
Proceedings of the National Academy of Sciences of the United States of America
2025-06-24
Mitchell Hayes,Wei Wang,Isabela Fraga de Andrade,Paul F Lambert,Bill Sugden
Kaposi sarcoma-associated herpesvirus cooperates with Epstein-Barr virus to co-transform a small set of human B cells oncogenically
PLoS pathogens
2025-06-23
Xiaofei Guan,Yanjie Zhu,Jian Zhong,Edmund Hollis
Neuropathic Pain-Like Responses in a Chronic CNS Injury Model Are Mediated by Corticospinal-Targeted Spinal Interneurons
The Journal of neuroscience : the official journal of the Society for Neuroscience
2025-06-23
Aubrey Converse,Madeline J Perry,Shweta S Dipali,Jose V V Isola,Emmett B Kelly,Joseph M Varberg…
Multinucleated giant cells are hallmarks of ovarian aging with unique immune and degradation-associated molecular signatures
PLoS biology
2025-06-23
Wolfgang Sadee,Ian H Cheeseman,Audrey Papp,Maciej Pietrzak,Michal Seweryn,Xiaofei Zhou,Shili Lin…
Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability
Communications biology
2025-06-23
Valerie A Porter,Brad A Hobson,Alita J D'Almeida,Karen L Bales,Pamela J Lein,Abhijit J Chaudhari
Three-dimensional U-Net with transfer learning improves automated whole brain delineation from MRI brain scans of rats, mice, and monkeys
Computers in biology and medicine
2025-06-21
Moonjung Jung,Jungwoo Kim,Yeji Park,Isaac Ilyashov,Fan Yang,Haruna B Choijilsuren,Danielle Keahi…
ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway
The Journal of cell biology
2025-06-20
Matthew S Fischer,Holden T Rogers,Emily A Chapman,Song Jin,Ying Ge
Native Top-Down Proteomics of Endogenous Protein Complexes Enabled by Online Two-Dimensional Liquid Chromatography
Analytical chemistry
2025-06-20
Wan-Chen Cindy Lee,Duo-Sheng Wang,Arghya Deb,Yiling Zhu,X Peter Zhang
Asymmetric C-H Amination via Fe(III)-Metalloradical Catalysis Featuring α-Fe(IV)-Aminyl Radicals as Key Intermediates
Journal of the American Chemical Society
2025-06-19
Qiufen Jiang,Sherry Jingjing Wu,Gord Fishell,Chinfei Chen
Reciprocal interaction between cortical SST and PV interneurons in top-down regulation of retinothalamic refinement
Proceedings of the National Academy of Sciences of the United States of America
2025-06-18