Matthew Goelzer,Sean Howard,Anamaria G Zavala,Daniel Conway,Janet Rubin,Gunes Uzer
Depletion of SUN1/2 induces heterochromatin accrual in mesenchymal stem cells during adipogenesis
Communications biology
2025-03-14
Amelia R Tanner,Sarah N Cilvik,Marjorie A Nguyen,Evgenia Dobrinskikh,Russell V Anthony,Stephanie R…
A Two-Hour Fetal Glucagon Infusion Stimulates Hepatic Catabolism of Amino Acids in Fetal Sheep
International journal of molecular sciences
2025-03-13
Fangcong Dong,Andrew J Annalora,Iain A Murray,Debopriya Chakraborty,Denise M Coslo,Craig Marcus…
Phytochemical-Mediated Ah Receptor Activity Is Dependent on Dietary Context
Nutrients
2025-03-13
Yuqin Yin,Kathleen Z He,Jane Kirby,Ishraq A Haque,Xin Tang
Visualizing the Cellular and Subcellular Distribution of Fms-like Tyrosine Kinase 3 (Flt3) and Other Neuronal Proteins Using Alkaline Phosphatase (AP) Immunolabeling
International journal of molecular sciences
2025-03-13
Abraham L Bayer,Zoie Magri,Hayley Muendlein,Alexander Poltorak,Pilar Alcaide
MyD88 determines T cell fate through BCAP-PI3K signaling
Journal of immunology (Baltimore, Md. : 1950)
2025-03-12
Yoon Cho,Yu-Hsiang Chang,Kevin P Quirion,Zachary H Strong,Zachary J Dubey,Nam Nguyen,Seoyoung Lee…
Aryl halide cross-coupling via formate-mediated transfer hydrogenation
Nature chemistry
2025-03-12
Samuel R Parker,Xavier J Lee,Jonathan S Calvert,David A Borton
xDev: a mixed-signal, software-defined neurotechnology interface platform for accelerated system development
Journal of neural engineering
2025-03-11
Rebecka Amodei,Sonnet S Jonker,Evelyn Lazen,Casey C Nestor,Charles T Estill,Charles E Roselli
KNDy Neurons and the Control of the Gonadotropic Axis in the Midgestation Fetal Sheep
Endocrinology
2025-03-06
Ya-Ting Chang,Benjamin A Barad,Juliette Hamid,Hamidreza Rahmani,Brian M Zid,Danielle A Grotjahn
Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import
The Journal of cell biology
2025-03-06
Jeewoo Kim,Ariel Williams,Hannah Noh,Elizabeth A Jasper,Sarah H Jones,James A Jaworski,Megan M…
Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups
Nature communications
2025-03-06
Paul C Rosen,Samantha M Horwitz,Daniel J Brooks,Erica Kim,Joseph A Ambarian,Lidia Waidmann…
State-dependent motion of a genetically encoded fluorescent biosensor
Proceedings of the National Academy of Sciences of the United States of America
2025-03-06
Megan S Hager,Jason P Cook,Brian Bothner,David K Weaver
Untargeted metabolomic and transcriptomic analysis in spring and durum wheat reveals potential mechanisms associated with the early stem solidness phenotype and resistance to wheat stem sawfly
Frontiers in plant science
2025-03-06
Jade Moore,Jim Gkantalis,Ines Guix,William Chou,Kobe Yuen,Ann A Lazar,Matthew Spitzer,Alexis Combes…
Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade
Journal for immunotherapy of cancer
2025-03-06
Sahithya Sridharan Iyer,Jiangbo Wu,Thomas D Pollard,Gregory A Voth
Molecular mechanism of Arp2/3 complex activation by nucleation-promoting factors and an actin monomer
Proceedings of the National Academy of Sciences of the United States of America
2025-03-06
Robert C Noland,Sujoy Ghosh,Carlos J Crisanto,Antonio Aleman,McKenna K Chaney,Maitri K Chauhan…
Male mouse skeletal muscle lacking HuR shows enhanced glucose disposal at a young age
Frontiers in physiology
2025-03-06
Fei Gao,Holly Janes,Susan Buchbinder,Deborah Donnell
Active-Controlled Trial Design for HIV Prevention Trials With a Counterfactual Placebo
Statistics in medicine
2025-03-05
Chaoqi Mu,Jamie L Reed,Feng Wang,Xinqiang Yan,Ming Lu,John C Gore,Li Min Chen
Validation of qMT and CEST MRI as Biomarkers of Response to Treatment After Lumbar Spinal Cord Injury in Rats
NMR in biomedicine
2025-03-05
Sarah Samorodnitsky,Danielle Weise,Eric F Lock,Ken M Kunisaki,Alison Morris,Janice M Leung,Monica…
The lung proteome in HIV-associated obstructive lung disease
ERJ open research
2025-03-05
Deepan Thiruppathy,Oriane Moyne,Clarisse Marotz,Michael Williams,Perris Navarro,Livia Zaramela…
Absolute quantification of the living skin microbiome overcomes relic-DNA bias and reveals specific patterns across volunteers
Microbiome
2025-03-05
Yushu Ma,Chien-Hung Shih,Jinxiong Cheng,Hsiao-Chun Chen,Li-Ju Wang,Yanhao Tan,Yuan Zhang,Daniel D…
High-Throughput Empirical and Virtual Screening To Discover Novel Inhibitors of Polyploid Giant Cancer Cells in Breast Cancer
Analytical chemistry
2025-03-05
Duran Bao,Sudipa Maity,Lingpeng Zhan,Seungyeon Seo,Qingbo Shu,Christopher J Lyon,Bo Ning,Adrian…
Precise mycobacterial species and subspecies identification using the PEP-TORCH peptidome algorithm
EMBO molecular medicine
2025-03-04
Alyson March,Hao Wu,Regine Choe,Danielle S W Benoit
Optimizing Tissue-Engineered Periosteum Biochemical Cues to Hasten Bone Allograft Healing
Journal of biomedical materials research. Part A
2025-03-04
Emily Puumala,Meganathan Nandakumar,Bonnie Yiu,Peter J Stogios,Benjamin G Strickland,Robert…
Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans
Nature communications
2025-03-04
Elizabeth B Hutchinson,Jean-Philippe Galons,Courtney J Comrie,Thomas G Beach,Geidy E Serrano,Mark W…
Diffusion tensor subspace imaging of double diffusion-encoded MRI delineates small fibers and gray-matter microstructure not visible with single encoding techniques
Magnetic resonance in medicine
2025-03-04
Shane D Curry,Bryce M Bower,Sven A Saemundsson,Andrew P Goodwin,Jennifer N Cha
Binding affinity and transport studies of engineered photocrosslinkable affibody-enzyme-nanoparticle constructs
Nanoscale advances
2025-03-03
Xiaofei Zhang,Ruoxin Lan,Yongjun Liu,Venu G Pillarisetty,Danting Li,Chaohui L Zhao,Suparna A Sarkar…
Complement activation in tumor microenvironment after neoadjuvant therapy and its impact on pancreatic cancer outcomes
NPJ precision oncology
2025-03-03
Christopher A Sojdak,David A Polefrone,Hriday M Shah,Cassandra D Vu,Brandon J Orzolek,Pedro M…
Direct (LC-)MS Identification of Regioisomers from C-H Functionalization by Partial Isotopic Labeling
ACS central science
2025-03-03
Douglas H Chang,Joshua D Richardson,Myung-Ryul Lee,David M Lynn,Sean P Palecek,Reid C Van Lehn
Machine learning-driven discovery of highly selective antifungal peptides containing non-canonical β-amino acids
Chemical science
2025-03-03
Laura L Vollmer,Fang Liu,Bruce Nmezi,Guillermo Rodriguez Bey,Nathan Herdman,Tong Ying Shun,Albert…
A high throughput, high content screen for non-toxic small molecules that reduce levels of the nuclear lamina protein, Lamin B1
Scientific reports
2025-03-02
Valerie Le Sage,Bailee D Werner,Grace A Merrbach,Sarah E Petnuch,Aoife K O'Connell,Holly C Simmons…
Influenza A(H5N1) Immune Response among Ferrets with Influenza A(H1N1)pdm09 Immunity
Emerging infectious diseases
2025-03-02
Joe Kodama,Takeshi Oichi,Kevin J Wilkinson,Joshua M Abzug,Takashi Kaito,Motomi Enomoto-Iwamoto…
Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zone
Bone research
2025-03-02
Kai Zhang,Ching Wooen Sze,Hang Zhao,Jun Liu,Chunhao Li
Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity
Communications biology
2025-03-02
Milankumar Prajapati,Jared Z Zhang,Grace S Chong,Lauren Chiu,Courtney J Mercadante,Heather L…
Studies of Slc30a10 deficiency in mice reveal that intestinal iron transporters Dmt1 and ferroportin transport manganese
Cellular and molecular gastroenterology and hepatology
2025-03-02
Morkos A Henen,David McCall,David Jones,Natalie G Ahn,Beat Vögeli
Protocol for converting assigned nuclear Overhauser enhancement spectroscopy series peaks into exact distance restraints using MATLAB- or CYANA-eNORA
STAR protocols
2025-03-01
Alexander M Telenson,Ryan R Hsieh,Gabrielle J Cowen,Eoin P Sode,Jason M Kwon,Andy H Vo,Michele…
A novel, rapidly progressive ataxia due to a spontaneous Myo5a mutation in mice impairs transport proteins and alters mitochondria
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2025-03-01
Chris Jennings-Shaffer,David H Rich,Matthew Macaulay,Michael D Karcher,Tanvi Ganapathy,Shosuke…
Finding high posterior density phylogenies by systematically extending a directed acyclic graph
Algorithms for molecular biology : AMB
2025-02-28
Aneri Soni,Michael J Frank
Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit
eLife
2025-02-28
Charis Amber,Timothée M Petitjean,Giedre Sirvinskaite,Ryan T Steele,Breanna Sprague,Julius Domack…
Two-Step Constitutional Isomerization of Saturated Cyclic Amines Using Borane Catalysis
JACS Au
2025-02-28
Deepika Dahiya,Zsuzsanna Péter-Szabó,Manjula Senanayake,Sai Venkatesh Pingali,Wellington C Leite…
SANS investigation of fungal loosenins reveals substrate-dependent impacts of protein action on the inter-microfibril arrangement of cellulosic substrates
Biotechnology for biofuels and bioproducts
2025-02-28
Riley A Roberts,Bryan E Metze,Nicole Javaly,Theresa M McCormick,David R Stuart
Access to arynes from arenes via net dehydrogenation: scope, synthetic applications and mechanistic analysis
Chemical science
2025-02-28
Wallace B Thoreson,Thomas M Bartol,Nicholas H Conoan,Jeffrey S Diamond
The architecture of invaginating rod synapses slows glutamate diffusion and shapes synaptic responses
The Journal of general physiology
2025-02-28
Yuanyuan Bai,Anand Kumar Agrahari,Libo Zhang,Hai Yu,Xiaoxiao Yang,Zimin Zheng,William Su,Jingxin Fu…
EASyMap-Guided Stepwise One-Pot Multienzyme (StOPMe) Synthesis and Multiplex Assays Identify Functional Tetraose-Core-Human Milk Oligosaccharides
JACS Au
2025-02-28
A Papadopoulou,E M Litkowski,M Graff,Z Wang,R A J Smit,G Chittoor,I Dinsmore,N S Josyula,M Lin,J…
Insights from the largest diverse ancestry sex-specific disease map for genetically predicted height
NPJ genomic medicine
2025-02-27
Łukasz Wieteska,Alexander B Taylor,Emma Punch,Jonathan A Coleman,Isabella O Conway,Yeu-Farn Lin…
Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling
Nature communications
2025-02-26
Peihan J Huang,Yasra Arif,Maggie P Rempe,Jake J Son,Jason A John,Kellen M McDonald,Nathan M Petro…
High-definition transcranial direct-current stimulation of left primary motor cortices modulates beta and gamma oscillations serving motor control
The Journal of physiology
2025-02-26
John P Stasiak,K A Woerpel
Triethylamine-Catalyzed Cyclization of Unsaturated Hydroperoxides in the Presence of Triethylammonium Hydrochloride: A Synthesis of 1,2-Dioxanes
Organic letters
2025-02-26
Su'ad A Yoon,Kevin So,Joshua G Harrison,Vivaswat Shastry,Katherine Urie,Zach Gompert,Pedro Miura…
High Quality Diet Enhances Immune Response and Affects Gene Expression During Viral Infection in an Insect Herbivore
Molecular ecology
2025-02-26
Saku T Kijima,Takema Sasaki,Yuichiro Kikushima,Daisuke Inoue,Shingo Sakamoto,Yuki Kondo,Soichi…
Control of plasma membrane-associated actin polymerization specifies the pattern of the cell wall in xylem vessels
Nature communications
2025-02-26
Ling He,Daria Azizad,Kruttika Bhat,Angeliki Ioannidis,Carter J Hoffmann,Evelyn Arambula,Mansoureh…
Radiation-induced cellular plasticity primes glioblastoma for forskolin-mediated differentiation
Proceedings of the National Academy of Sciences of the United States of America
2025-02-26
Dhiraj K Singh,Mushtaq Ahmed,Sadia Akter,Vinay Shivanna,Allison N Bucşan,Abhishek Mishra,Nadia A…
Prevention of tuberculosis in cynomolgus macaques by an attenuated Mycobacterium tuberculosis vaccine candidate
Nature communications
2025-02-25
Matthew Egleston,Shridhar Bhat,A Hasan Howlader,Mario A Bianchet,Yi Liu,Laura Maria Lopez Rovira…
Inhibitors of SAMHD1 Obtained from Chemical Tethering to the Guanine Antiviral Acyclovir
Biochemistry
2025-02-24
Mikael G Pezet,Juan A Torres,Tania A Thimraj,Ivana Matkovic,Nadine Schrode,John W Murray,Anjali…
Human respiratory airway progenitors derived from pluripotent cells generate alveolar epithelial cells and model pulmonary fibrosis
Nature biotechnology
2025-02-24
Jessica R Kenneson,Christina Papini,Su Tang,Kathy Huynh,Chun-Hui Zhang,William L Jorgensen,Karen S…
Exploring Possible Drug-Resistant Variants of SARS-CoV-2 Main Protease (Mpro ) with Noncovalent Preclinical Candidate, Mpro61
ACS bio & med chem Au
2025-02-24
Feifei Yuan,Jihong Yang,Fanglin Ma,Zhe Hu,Vikas Malik,Ruge Zang,Dan Li,Xianle Shi,Xin Huang,Hongwei…
Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development
Nature communications
2025-02-23
S Amin Moosavi,Jordan S Feldman,Wilson Truccolo
Controllability of nonlinear epileptic-seizure spreading dynamics in large-scale subject-specific brain networks
Scientific reports
2025-02-22
Yingjiao Xue,Liang Zhu,Saumen Karan,Joseph D Locker,Craig Branch,Jinghang Zhang,Bang Hoang,Juan…
Distinct outcomes from targeted perturbations of the multi-subunit SCFSkp2 E3 ubiquitin ligase in blocking Trp53/Rb1-null prostate tumorigenesis
Communications biology
2025-02-22
Meghna Gupta,Nitesh Kumar Khandelwal,Andrew Nelson,Peter Hwang,Sergei Pourmal,Jeffrey L Bennett…
Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica
Science advances
2025-02-21
John R Dickson,Robert G R Sobolewski,Analiese R Fernandes,Joanna M Cooper,Zhanyun Fan,Mirra Chung…
Alzheimer disease-associated tau post-translational modification mimics impact tau propagation and uptake
Journal of neuropathology and experimental neurology
2025-02-21
Stephen E White,Tristin A Schwartze,Ananya Mukundan,Christina Schoenherr,Shashi P Singh,Maarten van…
TGM6 is a helminth secretory product that mimics TGF-β binding to TGFBR2 to antagonize signaling in fibroblasts
Nature communications
2025-02-21
Dong Liu,Hannah C Webber,Fuyun Bian,Yangfan Xu,Manjari Prakash,Xue Feng,Ming Yang,Hang Yang,In-Jee…
Optineurin-facilitated axonal mitochondria delivery promotes neuroprotection and axon regeneration
Nature communications
2025-02-20
Abigail R Fabiano,Malachy W Newman,Jenna A Dombroski,Schyler J Rowland,Samantha V Knoblauch,Jiro…
Applying Ultrasound to Mechanically and Noninvasively Sensitize Prostate Tumors to TRAIL-Mediated Apoptosis
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2025-02-20
Chloe A Briney,Jesslyn C Henriksen,Chenwei Lin,Lisa A Jones,Leif Benner,Addison B Rains,Roxana…
Muskelin is a substrate adaptor of the highly regulated Drosophila embryonic CTLH E3 ligase
EMBO reports
2025-02-20
Sarah M C Colbert,Lauren Lepow,Brian Fennessy,Nakao Iwata,Masashi Ikeda,Takeo Saito,Chikashi Terao…
Distinguishing clinical and genetic risk factors for suicidal ideation and behavior in a diverse hospital population
Translational psychiatry
2025-02-20
Niki Oldenburg,Douglas G Mashek,Lisa Harnack,Qi Wang,Emily N C Manoogian,Nicholas Evanoff,Donald R…
Time-restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial
Obesity (Silver Spring, Md.)
2025-02-20
Mi Zhou,Shuiqiao Liu,Yanan Wang,Bo Zhang,Ming Zhu,Jennifer E Wang,Veena Rajaram,Yisheng Fang,Weibo…
AIF3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis
Nature communications
2025-02-20
Md Asmaul Hoque,Clara Schweinzer,Jesse J Martinez,Friederike Tewes,Vittorio Sacchetti,Hansjörg…
Heterogeneous Fe-N-C Cocatalyst for Hydroquinone Oxidation Enables Aerobic Oxidation of Primary Alcohols to Aldehydes
Angewandte Chemie (International ed. in English)
2025-02-20
Yan Sun,Damian Houde,Roxana E Iacob,Jason Baird,Robert V Swift,Michael Holliday,Xuyan Shi,Simone…
Hydrogen/Deuterium Exchange and Protein Oxidative Footprinting with Mass Spectrometry Collectively Discriminate the Binding of Small-Molecule Therapeutics to Bcl-2
Analytical chemistry
2025-02-19
Camille Rumberger,Madison Armstrong,Martin Kim,Raquel Ponce,Josue Melendez,Melissa DeBiasse,Serena…
Selection Over Small and Large Spatial Scales in the Face of High Gene Flow
Molecular ecology
2025-02-19
Allen S W Oak,Amrit Bagchi,Matthew J Brukman,Joshua Toth,Jamie Ford,Ying Zheng,Arben Nace,Ruifeng…
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration
Science advances
2025-02-19
Rebekah E Dadey,Jian Cui,Dhivyaa Rajasundaram,Hiroshi Yano,Chang Liu,Jonathan A Cohen,Andrew W Liu…
Regulatory T cells in the tumor microenvironment display a unique chromatin accessibility profile
ImmunoHorizons
2025-02-18
Yaewon Kim,Tanner M Nickles,Philip M Lee,Robert A Bok,Jeremy W Gordon,Peder E Z Larson,Daniel B…
A data-driven approach for improved quantification of in vivo metabolic conversion rates of hyperpolarized [1-13 C]pyruvate
Magnetic resonance in medicine
2025-02-18
Noble Kumar Talari,Ushodaya Mattam,Afra P Rahman,Brook K Hemmelgarn,Michael A Wyder,Pamela B…
Functional compartmentalization of hepatic mitochondrial subpopulations during MASH progression
Communications biology
2025-02-18
Gabriella O Estevam,Edmond Linossi,Jingyou Rao,Christian B Macdonald,Ashraya Ravikumar,Karson M…
Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
eLife
2025-02-17
Tuan Anh Trinh,Stanislav Cherempei,Daniel S Rampon,Jennifer M Schomaker
Site- and stereoselective silver-catalyzed intramolecular amination of electron-deficient heterobenzylic C-H bonds
Chemical science
2025-02-14
Linnea S Dolph,Emma E Santa,Irene M Stoutland,Kelsey M Mesa,Cole C Dickson,Helen E Blackwell…
Silyl-Lipid Functionalized N-Acyl Homoserine Lactones as Modulators of Bacterial Cell-Cell Communication
ACS chemical biology
2025-02-13
Jiabo Li,Ling-Kai Shih,Steven M Markwell,Cheryl L Olson,David P Sullivan,Constadina Arvanitis,James…
A clinically relevant model and method to study necrosis as a driving force in glioma restructuring and progression
Proceedings of the National Academy of Sciences of the United States of America
2025-02-13
Paige J Monsen,Prashant V Bommi,Arabela A Grigorescu,Kristen L Lauing,Yingyu Mao,Payton Berardi…
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
Journal of medicinal chemistry
2025-02-13
Nitesh Kumar Khandelwal,Meghna Gupta,Paras Kumar,Sree Ganesh Balasubramani,Ignacia Echeverria…
Structural basis of disease mutation and substrate recognition by the human SLC2A9 transporter
Proceedings of the National Academy of Sciences of the United States of America
2025-02-12
Samantha J Knott,Trisha Tucholski,Harini Josyer,David Inman,Andreas Friedl,Yanlong Zhu,Ying Ge…
Deciphering Proteoform Landscape of Mammary Carcinoma by Top-Down Proteomics
Journal of proteome research
2025-02-12
Carly K Schissel,Helena Roberts-Mataric,Isaac J Garcia,Hana Kang,Riaz Mowzoon-Mogharrabi,Matthew B…
Peptide Backbone Editing via Post-Translational O to C Acyl Shift
Journal of the American Chemical Society
2025-02-11
Brian J North,Amelia E Ohnstad,Michael J Ragusa,Christopher J Shoemaker
The LC3-interacting region of NBR1 is a protein interaction hub enabling optimal flux
The Journal of cell biology
2025-02-10
Christopher Langdon,Tatiana A Engel
Latent circuit inference from heterogeneous neural responses during cognitive tasks
Nature neuroscience
2025-02-10
Caroline Williams,Bella R Carnahan,Stephen N Hyland,Kristen E DeMeester,Catherine L Grimes
Bio-orthogonal Labeling of Chitin in Native Pathogenic Candida Species via the Chitin Scavenge Pathway
Journal of the American Chemical Society
2025-02-10
Xiaoyu Zhang,Yan Liu,Ning Wang
Dynamic changes in histone lysine lactylation during meiosis prophase I in mouse spermatogenesis
Proceedings of the National Academy of Sciences of the United States of America
2025-02-10
Jared Almazan,Tursun Turapov,David A Kircher,Karly A Stanley,Katie Culver,A Paulina Medellin…
Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases
Cell reports. Medicine
2025-02-08
Hirohide Takatani,Naoki Fujita,Fumiyasu Imai,Yutaka Yoshida
Modulation of Extrinsic and Intrinsic Signaling Together with Neuronal Activation Enhances Forelimb Motor Recovery after Cervical Spinal Cord Injury
eNeuro
2025-02-07
Christopher J DeAngelis,Geeta Goyal,Marshall J Liss,Jessica E Budwitz,Mary Stuart Herlihy,Audrey V…
Ketenimines as Aza-Dienophiles
Journal of the American Chemical Society
2025-02-07
Emily D Ziperman,Kate B Fitzpatrick,Malavika A Nair,Alexander W Sorum,Linda C Hsieh-Wilson,Isaac J…
A system for in vitro selection of fully 2'-modified RNA aptamers
Organic & biomolecular chemistry
2025-02-06
Joseph W Treacy,James A R Tilden,Elaine Y Chao,Zihuan Fu,Alexander M Spokoyny,K N Houk,Heather D…
In silico screening of P,N-ligands facilitates optimization of Au(iii)-mediated S-arylation
Chemical science
2025-02-06
Seth A Cory,Cheng-Wei Lin,Shachin Patra,Steven M Havens,Christopher D Putnam,Mehdi Shirzadeh,David…
Frataxin Traps Low Abundance Quaternary Structure to Stimulate Human Fe-S Cluster Biosynthesis
Biochemistry
2025-02-05
Subash Khadka,Brandon Lukas,Claire Xin Sun,Sribalashubashini Muralimanoharan,Karthigayan…
Mediator kinase inhibition drives myometrial stem cell differentiation and the uterine fibroid phenotype through super-enhancer reprogramming
Journal of molecular medicine (Berlin, Germany)
2025-02-04
Lyndsey E Shorey-Kendrick,B Adam Crosland,Matthias C Schabel,Ilhem Messaoudi,Minzhe Guo,Matthew G…
Effects of maternal edible THC consumption on offspring lung growth and function in a rhesus macaque model
American journal of physiology. Lung cellular and molecular physiology
2025-02-04
Sophia J Bailey,Noah Eckman,Elisa S Brunel,Carolyn K Jons,Samya Sen,Eric A Appel
A thiol-ene click-based strategy to customize injectable polymer-nanoparticle hydrogel properties for therapeutic delivery
Biomaterials science
2025-02-03
Jae Mo Park,Sung-Han Lin,Jeannie D Baxter,Crystal E Harrison,Jennine Leary,Corey Mozingo,Jeff…
Disrupted metabolic flux balance between pyruvate dehydrogenase and pyruvate carboxylase in human fatty liver
Metabolism: clinical and experimental
2025-01-31
Amirhossein Abazarikia,Yi Luan,Wonmi So,Michelle Becker,Sipra Panda,Samantha A Swenson,Elizabeth A…
Leukemic Cells Infiltrate the Ovaries Without Damaging Ovarian Reserve in an Acute Myeloid Leukemia Mouse Model
Endocrinology
2025-01-31
Hyunwoo Ju,Il-Doo Kim,Ina Pavlova,Shang Mu,Keun Woo Park,Joseph Minkler,Ahmed Madkoor,Wei Wang…
Ischemic Conditioning Promotes Transneuronal Survival and Stroke Recovery via CD36-Mediated Efferocytosis
Circulation research
2025-01-31
Vasanthakrishna Mundodi,Saket Choudhary,Andrew D Smith,David Kadosh
Ribosome profiling reveals differences in global translational vs transcriptional gene expression changes during early Candida albicans biofilm formation
Microbiology spectrum
2025-01-28
Danielle T Little,Caitlin M Howard,Emma Pendergraft,Kenneth R Brittian,Timothy N Audam,Exile W…
Activated cardiac fibroblasts are a primary source of high-molecular-weight hyaluronan production
American journal of physiology. Cell physiology
2025-01-28
Alva G Sainz,Gladys R Rojas,Alexandra G Moyzis,Matthew P Donnelly,Kailash C Mangalhara,Melissa A…
FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion
The Journal of cell biology
2025-01-27
Yihu Xie,Bradley P Clarke,Dongqi Xie,Menghan Mei,Prasanna Bhat,Pate S Hill,Alexia E Angelos,Tolga…
Structures and mRNP remodeling mechanism of the TREX-2 complex
Structure (London, England : 1993)
2025-01-25
Harm J van der Horn,Tracey V Wick,Josef M Ling,Jessica R McQuaid,Upasana Nathaniel,Samuel D Miller…
Trajectories of intrinsic connectivity one year post pediatric mild traumatic brain injury: Neural injury superimposed on neurodevelopment
Cortex; a journal devoted to the study of the nervous system and behavior
2025-01-24
Sarah Lanning,Nayeli Aguilar-Hernández,Vitor Hugo B Serrão,Tomás López,Sara M O'Rourke,Adam Lentz…
Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization
Journal of virology
2025-01-23
Derek G Wu,Cassandra R Harris,Katie M Kalis,Malique Bowen,Jennifer F Biddle,Ibrahim F Farag
Comparative metagenomics of tropical reef fishes show conserved core gut functions across hosts and diets with diet-related functional gene enrichments
Applied and environmental microbiology
2025-01-22
A Dimitrios Colevas,Zahra Talebi,Elizabeth Winters,Caroline Even,Victor Ho-Fun Lee,Maura L Gillison…
First-in-Human Clinical Trial of a Small-Molecule EBNA1 Inhibitor, VK-2019, in Patients with Epstein-Barr-Positive Nasopharyngeal Cancer, with Pharmacokinetic and Pharmacodynamic Studies
Clinical cancer research : an official journal of the American Association for Cancer Research
2025-01-20
Nicholas Richards,Michael Malmberg,Henrik Odéen,Sara Johnson,Michelle Kline,Robb Merrill,Rock…
In vivo simultaneous proton resonance frequency shift thermometry and single reference variable flip angle T1 measurements
Magnetic resonance in medicine
2025-01-20
Alyson March,Tayler S Hebner,Regine Choe,Danielle S W Benoit
Leveraging the predictive power of a 3D in vitro vascularization screening assay for hydrogel-based tissue-engineered periosteum allograft healing
Biomaterials advances
2025-01-19
Mandakh Bekhbat,Andrew M Block,Sarah Y Dickinson,Gregory K Tharp,Steven E Bosinger,Jennifer C Felger
Neurotransmitter and metabolic effects of interferon-alpha in association with decreased striatal dopamine in a non-human primate model of cytokine-Induced depression
Brain, behavior, and immunity
2025-01-18
Fumiaki Ito,James Zhen,Guodong Xie,Haigen Huang,Juan C Silva,Ting-Ting Wu,Z Hong Zhou
Structure of the Kaposi's sarcoma-associated herpesvirus gB in post-fusion conformation
Journal of virology
2025-01-17
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