Michaela Medina,Ya-Ting Chang,Hamidreza Rahmani,Mark Frank,Zidan Khan,Daniel Fuentes,Frederick A…
Surface Morphometrics reveals local membrane thickness variation in organellar subcompartments
The Journal of cell biology
2025-12-31
Scotty G McKay,Yongsheng Chen,E Mark Haacke,Yang Xuan,Aimee F Luat,Csaba Juhász
Clinical Validation of a Fast MRI Method to Evaluate Brain Vascular and Parenchymal Abnormalities in Sturge-Weber Syndrome
Journal of magnetic resonance imaging : JMRI
2025-12-30
Roberta S Dos Reis,Lauren A Ignatz,Sathish Selvam,Marc C E Wagner,Sara Gianella,Antoine Chaillon…
Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV-1
Brain pathology (Zurich, Switzerland)
2025-12-30
Yuancheng Jiang,Yohan Jun,Qiang Liu,Wen Zhong,Yogesh Rathi,Hua Guo,Berkin Bilgic
Multishot Dual Polarity GRAPPA: Robust Nyquist Ghost Correction for Multishot EPI
Magnetic resonance in medicine
2025-12-26
Guitao Bai,Tangliang Shen,MohammadHossein Shabahang,Shumin Bao,Shuquan Fan,Hongshuai Lv,Lei Li
Divergent Enzymatic Synthesis of a Comprehensive Type‑1 Glycan Determinant Library
ACS catalysis
2025-12-25
Teri Lawton,John Shelley-Tremblay,Roland R Lee,Ming-Xiong Huang
Retraining dorsal visual pathways improves cognitive skills and executive control networks following mild traumatic brain injury
Frontiers in human neuroscience
2025-12-25
Liam H Power,Evan C Marcet,Zihong Chen,Jinpeng Chen,Artem Arkhangelskiy,Michael J Whalen,Ying Chen…
Three-Dimensional Human Neurovascular Unit Modeling Reveals Cell-Specific Mechanisms of Traumatic Brain Injury
Journal of functional biomaterials
2025-12-24
Whitney Nicole Bergman,Marcelo Carlos Sousa
A fluorescent reporter and single-turnover kinetics reveal insight into BAM complex function
Proceedings of the National Academy of Sciences of the United States of America
2025-12-24
Somayeh Zeinalilathori,Ryan W Russell,Jean L Ross,Shannon Modla,Jeffrey L Caplan,Tatyana Polenova…
Structure of the disulfide-rich modules of a striking tandem repeat protein, avian cysteine-rich eggshell membrane protein
Protein science : a publication of the Protein Society
2025-12-23
Stephanie Stransky,Sarah Graff,Kai Mao,Derek M Huffman,Sofiya Milman,Nir Barzilai,Simone Sidoli
Preliminary Evidence for Increased Histone Succinylation as a Potential Epigenetic Marker for Longevity
Aging cell
2025-12-23
Ravi Shankar Palani,Christopher G Williams,Dev Thacker,Robert Silvers,Fang Qian,Paul H Weinreb…
Aducanumab binding to Aβ1-42 fibrils alters dynamics of the N-terminal tail while preserving the fibril core
Proceedings of the National Academy of Sciences of the United States of America
2025-12-22
John Mutersbaugh,Wan-Chun Su,Anjana Bhat,Amir Gandjbakhche
Deep Learning Approaches for Classifying Children With and Without Autism Spectrum Disorder Using Inertial Measurement Unit Hand Tracking Data: Comparative Study
JMIR medical informatics
2025-12-22
Viola Rieke,Allison Payne,Robb Merrill,J Rock Hadley,Henrik Odéen,Michelle Kline,Matthew S…
Design and evaluation of a magnetic resonance-guided focused ultrasound system for the treatment of cervical spine pain
Medical physics
2025-12-21
Erica Braverman,Mengtao Qin,Elisabet Ampudia-Mesias,Herbert Tres Schuler,Harrison Brown,Lukas…
AMPK agonism optimizes the in vivo activation and antileukemic efficacy of chimeric antigen receptor T cells
Journal for immunotherapy of cancer
2025-12-21
Jessica Burnier,Clement Gallay,Kevin E Bruce,Elisabet Bjånes,Louise Martin,Kin Ki Jim,Ho-Ching…
Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials
Nature microbiology
2025-12-19
Joshua M Mesfin,Alexander Chen,Quincy P Lyons,Michael B Nguyen,Maria L Karkanitsa,Justin Yu,Van K…
Infusible Extracellular Matrix Biomaterial Enhances Cell-Specific Pro-Repair Responses Following Acute Myocardial Infarction
Advanced healthcare materials
2025-12-19
Rémi Patriat,Jayashree Chandrasekaran,Karianne Sretavan,Henry Braun,Samuel Brenny,Yasamin Seddighi…
"PICS": a novel patient-specific landmark for thalamic surgical interventions in the posterior limb of the internal capsule signal
Frontiers in human neuroscience
2025-12-18
Minnuo Cai,Hang Lei,Yuetong Zhang,Jiaxiang Zou,Wanjing Cao,Yiquan Wang,Kai Wei
APOE ε 4 -Associated Hippocampal Atrophy Trajectories Across the Alzheimer's Disease Continuum: A Systematic Review, Meta-Analysis, and Longitudina...
medRxiv : the preprint server for health sciences
2025-12-18
Richa Singhal,Ilaria Ferrari,Robert E Brainard,Kenneth R Brittian,Julia Chariker,Helen E Collins…
Temporal Dynamics in Murine Cardiac Transcriptome Following Myocardial Infarction
Circulation research
2025-12-18
Kelsey C Muir,Christopher Stone,Riya Reddy,Meghamsh Kanuparthy,Jad Hamze,Dwight D Harris,M Ruhul…
Sotagliflozin Enhances Left Ventricular Function and Myocardial Perfusion in Chronic Myocardial Ischemia Through Metabolic and Redox Remodeling
Arteriosclerosis, thrombosis, and vascular biology
2025-12-18
Hélène Tonnelé,Denghui Chen,Felipe Morillo,Jorge Garcia-Calleja,Apurva S Chitre,Benjamin B Johnson…
Genetic architecture and mechanisms of host-microbiome interactions from a multi-cohort analysis of outbred laboratory rats
Nature communications
2025-12-18
Xiaohan Kuang,Yunchao Lance Liu,Xiaobo Lin,Jesse Spencer-Smith,Tyler Derr,Yinghao Wu,Hans Bitter…
Superwater as a generative AI framework to predict water molecule positions on protein structures
Communications chemistry
2025-12-18
Yu Zhao,Ruoxin Li,Pingchuan Liu,Jialiang Wang,Yanru Cui,Yufei Ma,Zeyu Cao,Meng Cui,Sijin Luozhong…
Low reactogenicity and high tumour antigen expression from mRNA-LNPs with membrane-destabilizing zwitterionic lipids
Nature biomedical engineering
2025-12-18
Tingting Li,Peilin Zhu,Jialing Wang,Tao Zhang,Joseph Adams,Fei Tu,Chloe Garbe,Xiaojin Zhang,Li Liu…
Heme drives cardiac endothelial senescence in sepsis via STING activation
Cell death & disease
2025-12-18
Zhenyu Zhang,Isabel Uribe,Kaitlin A Davis,Robert L McPherson,Gloria P Larson,Mohsen Badiee,Vy Tran…
Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection
Nature communications
2025-12-17
Xuwen Liu,Enming J Su,Alyssa Dreffs,John P Gillies,Madeline Merlino,Lu Gao,Julian S Peregoff,Cheng…
Occludin acts as a dynein adaptor regulating permeability and collateral angiogenesis
Proceedings of the National Academy of Sciences of the United States of America
2025-12-16
Daniel L Aldridge,Zachary Lanzar,Anthony T Phan,David A Christian,Ryan D Pardy,Booki Min,Ross Kedl…
IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion
eLife
2025-12-15
Samantha L Goldschmid,Holly L Hutchinson,Trevor C Sherwood,Candice L Joe,Eric R Welin,Tomislav Rovis
Engaging Tertiary Benzylic Radicals in Metallaphotoredox Catalysis: A Modular Approach to Access Diaryl Quaternary Centers
Angewandte Chemie (International ed. in English)
2025-12-15
Ronald Cutler,Laura Corveleyn,Claudia Ctortecka,Francesca LiCausi,Joshua Cantlon,Alvaro Sebastian…
Mass spectrometry-based profiling of single-cell histone post-translational modifications to dissect chromatin heterogeneity
Nature communications
2025-12-12
Daniel P Caron,William L Specht,Siddhi Nargund,David Chen,Steven B Wells,Jennifer Hwu,Peter A Szabo…
Tissue signatures of human macrophages during homeostasis and activation
Journal of immunology (Baltimore, Md. : 1950)
2025-12-12
Yuqing Hou,Oranti Ahmed Omi,Michael W Stuck,Xi Cheng,Bethany Walker,Ying-Wai Lam,Anna M Schmoker…
Activation of the ciliary kinase CDKL5 is mediated by the cyclin-dependent kinase CDK20/LF2 to control flagellar length
PLoS biology
2025-12-12
Antony Lurie,Christina A Stephens,David M Kern,Katharine M Henn,Naomi R Latorraca,Stephen G Brohawn
Assembly and lipid-gating of LRRC8A:D volume-regulated anion channels
Nature communications
2025-12-12
Juan I Bravo,Eyael Tewelde,Christina D King,Joanna Bons,Samah Shah,Jacob Rose,Judith Campisi,Birgit…
A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways
GeroScience
2025-12-11
Chia-Yu Kang,Minjun An,Sahar Heidari,Hedieh Torabifard,Melanie D Ohi,Randy B Stockbridge
The molecular mechanism of fluoride export by the eukaryotic fluoride channel FEX
Nature communications
2025-12-11
Aditya Banerjee,Sophie Pickelner,Faith Smith,Livia M A Tenuta,Randy B Stockbridge
Fluoride triggers lysis in Streptococcus mutans by inhibition of the Clp protease complex, leading to an unabated competence cascade
Proceedings of the National Academy of Sciences of the United States of America
2025-12-11
Qiu C Wu,Aishwarya Swaminathan,Ashley Winward,Logan Lalonde,Yung Hwang,Noah Littman,Merav…
IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin
PLoS biology
2025-12-11
Fang Li,Bibek Poudel,Magaiver Andrade-Silva,Junnan Wu,Archana Raman,Elisa Cruz-Morales,Joseph Wahba…
Cell-Specific Inducible Human APOL1 Risk Variant Expression in Mice Causes Hypertension and Renal Damage
Circulation
2025-12-11
Fei Wang,Victor Banerjee,Carla Barria,Santiago Ramirez,Tyler Allison,Damian Gorski,Haley Evans…
Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates
Nature communications
2025-12-10
Alexandria S Battison,Jeremy L Balsbaugh,Jeremy C Borniger
APEX2 and TurboID define unique subcellular proteomes
Scientific reports
2025-12-10
Poonam Roshan,Vikas Kaushik,Ayush Mistry,Abhinav Vayyeti,Aidan Antony,Riley Luebbers,Jaigeeth…
Mechanism of RPA phosphocode priming and tuning by CDK1/WEE1 signaling circuit
Nature communications
2025-12-09
Timothy J Trinklein,Stanislav S Rubakhin,Samuel Okyem,Seth W Croslow,Marisa Asadian,K R Sabitha…
Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in Alzheimer's disease mouse models
Nature communications
2025-12-09
Anna Potapova,Rino Oguchi,Steffi Jimmy,Christopher R Evans,Kaitlin D Yarrington,James B Winans…
Vibrio cholerae biofilm matrix assembly and growth are shaped by a glutamate-specific TAXI/TRAP protein
Proceedings of the National Academy of Sciences of the United States of America
2025-12-09
Alexander F Lesser,Aura Perez,Chunying Wu,Shuyu Hao,Bernadette Erokwu,Derek Host,Anjum Jafri,Elisha…
Intestinal adaptations increase basolateral intestinal glucose uptake and glycolysis in a mouse model of Cystic Fibrosis
American journal of physiology. Gastrointestinal and liver physiology
2025-12-09
Xianting Hu,Zhi Liu,Yao Li,Yannan You,Kaiye Yue,Yuqiong Liang,Chin-San Loo,Jingting Yu,Matthias…
REV-ERB regulates RORγt+ regulatory T cell specification and function through the Bhlhe40-c-Maf axis
The Journal of experimental medicine
2025-12-08
Aayushi Singh,Francesco Pettini,Beatrice Gianibbi,Sayan Das,Donatella Barisani,Jeffrey A Purslow…
Structure-based Discovery of a Non-competitive FTO Inhibitor Bound to a Cryptic Site at the Domain Interface
Journal of molecular biology
2025-12-07
Ke Wang,Shayan Saniei,Nikita Poddar,Isabella G Martinez,Clifford Chao,Subrina Autar,Persephone…
Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia
Cancer discovery
2025-12-06
Ramon Mendoza Uriarte,Benoît Roux
Force field sensitivity of ion occupancy in potassium channels
Biophysical journal
2025-12-06
Sofia Bali,Pawel M Wydorski,Ruhar Singh,Nico E Van Nuland,Aleksandra Wosztyl,Nabil Morgan,Valerie A…
Amyloid-motif-dependent tau self-assembly is modulated by isoform sequence context
Structure (London, England : 1993)
2025-12-06
Quan Jiang,Ling-Xiao Shao,Shenqin Yao,Neil K Savalia,Amelia D Gilbert,Pasha A Davoudian,Jack D…
Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks
Cell
2025-12-06
Rose Z Hill,Jonathan W Nelson,Georgina Gyarmati,Silvia Medrano,Sepenta Shirvan,James A McCormick…
Renal PIEZO2 is an essential regulator of renin
Cell
2025-12-05
Daniela Torres-Hernández,Nathan D Grubaugh,Mónica A Murillo-Ortiz,Isabel C Hurtado,Verity Hill…
Epidemiology and severity risk factors of dengue virus infection during the 2023-2024 outbreak in Colombia
PLoS neglected tropical diseases
2025-12-05
Kristen C Vogt,Magdalini Panagiotakopoulou,Mandana T Manzari Honu,Ana Marie Perea,Xiaoping Hu,Xufen…
Tumor microenvironment-targeted PROTAC nanoparticle self-assembly broadly predicted by structural descriptors
Science advances
2025-12-05
Marianela G Dalghi,Wily G Ruiz,Dennis R Clayton,Tanmay Parakala-Jain,Marcelo D Carattino,Yun Stone…
Conditional deletion of Tmem63b does not impact mouse voiding behavior
PloS one
2025-12-05
Natalia Malina,Rodney Tollerson,Shifat J Monami,Elyssa Rivera,Ming-Kuo Lee,Laura D Bilenker,Ann…
Microbial community diversity and geochemistry inform bioremediation of molybdenum-contaminated groundwater
Applied and environmental microbiology
2025-12-05
Aditya Parmar,Sanjay K Nigam,Kun Cai,Kian Falah,Vladimir S Ermakov,Kelly Wang,Cole J Ferguson
Developmentally dynamic chromatin state at loci regulating organ crosstalk by remote sensing and signaling
Epigenetics & chromatin
2025-12-04
Sultan Almunif,Simseok A Yuk,El Hadji Arona Mbaye,Swagat Sharma,Michael D Purdy,Sandeep Kumar…
Engineering the Size of Bicontinuous Nanospheres via Multi-Inlet Vortex Mixing
Nano letters
2025-12-04
Shashank Srivastava,Daniela Samaniego-Castruita,Shubhi Srivastava,Sakshi Khurana,Jalees Rehman…
Rate-limiting enzymes in nucleotide metabolism synchronize nucleotide biosynthesis and chromatin formation
Molecular cell
2025-12-04
Rasim S Diler,Farzan Vahedifard,Boris Birmaher,Satish Iyengar,Maria Wolfe,Brianna N Lepore,Mariah…
Differentiating Pediatric Bipolar Disorder, Attention-Deficit/Hyperactivity Disorder, and Other Psychopathologies Using Self-Reported Mood and Energy Data and Actigraphy Findings: Correlation and Machine Learning-Based Prediction of Mood Severity
JMIR mental health
2025-12-04
Maricarmen Pachicano,Shrey Mehta,Angela Hurtado,Tyler Ard,Jim Stanis,Bayla Breningstall,Michael S…
Laminar organization of pyramidal neuron cell types defines distinct CA1 hippocampal subregions
Nature communications
2025-12-03
Andrew P Anderson,Sanghyun Kim,Allison J Melton,Xiaoyun Ding,Wei Zhang,Alexander B Saltzman,Anna…
A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment
Nature communications
2025-12-03
Sydney E Parks,Suni Tang,Anna Catherine Unser,Ananya L Bhonsley,Eunbi M Chung,Peixin Jiang,Audrey…
TGFBR2 coordinates the endometrial response to estrogen, regulating endometrial hyperplasia and fertility
Proceedings of the National Academy of Sciences of the United States of America
2025-12-03
Andrew Olson,Sunita Kumari,Xuehong Wei,Kapeel Chougule,Zhenyuan Lu,Marcela Karey Tello-Ruiz,Vivek…
Gramene 2025: expanded comparative genomics and pathway resources, integrated search, and pan-genome portals for crop research
Nucleic acids research
2025-12-03
Yang Zhang,Maria Savvidou,Volha Liaudanskaya,Varshini Ramanathan,Thi Bui,Matthew Lindley,Yuhang Fu…
Multi-modal label-free imaging of cellular metabolism and oxidative stress in 3D brain tissue models
Communications biology
2025-12-02
John Kim,Anna Page,Ryan T Vanderlinden,Ryan E Looper
A diastereoselective preparation of cyclic α-aminoboronates
Tetrahedron letters
2025-11-28
Chris Foley,Rachael A Floreani
Impact of Whey Protein on the Physico-Mechanical Properties of Alginate Dialdehyde Scaffolds and Cell Adhesion for Cultivated Meat Applications
Food hydrocolloids
2025-11-28
Suhas Sureshchandra,James Henderson,Elizabeth Levendosky,Sankalan Bhattacharyya,Jenna M…
Deep profiling of human T cells defines compartmentalized clones and phenotypic trajectories across blood and tonsils
Immunity
2025-11-27
Jia J Li,Alessandro Vasciaveo,Dimitris Karagiannis,Zhen Sun,Kristjan H Gretarsson,Xiao Chen,Ouathek…
NSD2 targeting reverses plasticity and drug resistance in prostate cancer
Nature
2025-11-26
Justin L Korfhage,Helin Elhan,Neng Wan,Yingying Lu,Lisa Kauffmann,Govindaiah Pilli,Devin M Fuller…
ATG2 is a triglyceride transfer protein
Proceedings of the National Academy of Sciences of the United States of America
2025-11-26
Erin E Doherty,Jason Nomburg,Benjamin A Adler,Santiago Lopez,Kendall Hsieh,Nathan Price,Nurashau…
Divergent viral phosphodiesterases for immune signaling evasion
Cell host & microbe
2025-11-26
Changho Choi,Mai Huynh,Zoltan Kovacs,William J Behof,Wellington Pham,Sandeep K Ganji,Zhongxu An…
Magnetic Resonance Spectroscopy of Cystathionine and 2-Hydroxyglutarate in Brain Tumors
NMR in biomedicine
2025-11-25
John T Killian,R Glenn King,Aaron C K Lucander,James L Kizziah,Christopher F Fucile,Ruben Diaz…
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients
Immunity
2025-11-25
Ruben I Calderon,Nirvay Sah,Molly Huang,Sampada Kallol,Ryan H Kittle,Walee B Shaik,Ahmed Abdelbaki…
VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment
Proceedings of the National Academy of Sciences of the United States of America
2025-11-24
Chris Jennings-Shaffer,Cherith Chen,Julia A Palacios,Frederick A Matsen Iv
Generalizing matrix representations to fully heterochronous ranked tree shapes
ArXiv
2025-11-24
Marvic Carrillo Terrazas,Renee E Oles,Luke R Loomis,Chia-Yun Hsu,Adriana Vasquez Ayala,Michael H…
Antimicrobial resistance is widespread among intestinal and extra-intestinal Bacteroides fragilis strains
Infection and immunity
2025-11-24
Kuan Yu,Aikaterini Gorou,Danny Huang,Thomas J Maimone
Short, Enantioselective Total Synthesis of (+)-Ineleganolide
Journal of the American Chemical Society
2025-11-21
Katia Corano Scheri,Yi-Wen Hsieh,Thomas Tedeschi,James B Hurley,Amani A Fawzi
Müller cell glutamine metabolism links photoreceptor and endothelial injury in diabetic retinopathy
Life science alliance
2025-11-20
Jennifer T Aguilan,Carlos Madrid-Aliste,Joshua Fischer,Maria K Lagou,Simone Sidoli,George S…
Identifying space-resolved proteins of the murine thymus, by combining MALDI-MSI and proteomics
Life science alliance
2025-11-20