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IRF6 C-terminal phosphorylation links inflammation and cell-cell adhesion in oral keratinocytes: implications for oral lichen planus
BMC immunology
2025-10-08
Dev R Mehrotra,Carolina V Cordova,Tianbai Wang,Erik E Ersland,Juncheng Zhang,Steven J Staffa,Thomas…
Evaluation of Engineered Cartilage Composition and Function Using Raman Spectroscopy
Advanced healthcare materials
2025-10-06
Xiao-Wen Zhang,Le Yin,Dakang Zhang,Zixiang Jiang,Pinzhi Wang,Hao Xu
Iron-Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides
Angewandte Chemie (International ed. in English)
2025-10-03
Shivraj M Yabaji,Vadim Zhernovkov,Prasanna Babu Araveti,Suruchi Lata,Oleksii S Rukhlenko,Salam Al…
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility
eLife
2025-10-02
Vaishnavi Aradhyula,Sareeta Manandhar,Alborz Sherafati,Alex Kloster,Anas Fares,Prabhatchandra Dube…
Circulating oxylipins predict mortality in heart failure with preserved ejection fraction
ESC heart failure
2025-10-01
Zefeng Zhou,Yang Wang,Wei-Shang Lo,Gavin J Giardino,Kanika Lalit,Michael Goldstein,Wenqi Wang,Chloe…
Processive ring-opening metathesis polymerization of low ring strain cycloalkenes via molecularly confined catalyst
Nature communications
2025-10-01
Hua Bai,Jake J Son,Nathan M Petro,Danielle L Rice,Grace C Ende,Ryan J Glesinger,Hannah J Okelberry…
Dynamic developmental signatures of facial expression processing differ by emotion
Communications biology
2025-10-01
B Vijayalakshmi Ayyar,Carmen V Apostol,Janam Jitendra Dave,Soni Kaundal,Joseph A Kendra,Frederick H…
Functional diversity in GII.4 norovirus entry: HBGA binding and capsid clustering dynamics
Proceedings of the National Academy of Sciences of the United States of America
2025-10-01
Xun Wu,Ziyi Wang,Katherine R Croce,Fang Li,Jian Cui,Vivette D D'Agati,Rajesh K Soni,Ira Tabas,Ai…
Macrophage WDFY3 mitigates autoimmunity by enhancing efferocytosis and suppressing T cell activation in mice
Nature communications
2025-09-30
Steven P Maher,Malina A Bakowski,Amélie Vantaux,Erika L Flannery,Chiara Andolina,Mohit Gupta…
A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites
eLife
2025-09-30
Elizabeth Voke,Mariah L Arral,Henry J Squire,Teng-Jui Lin,Lining Zheng,Roxana Coreas,Alison Lui…
Protein corona formed on lipid nanoparticles compromises delivery efficiency of mRNA cargo
Nature communications
2025-09-30
Jiawan Wang,Arnab Sarkar,Natalia Garcia,Lindy Zhang,Ana Calizo,Alla Lisok,Katia Campos,Funan He…
Selective inhibition of BRAF and CRAF sensitizes NF1-deficient malignant peripheral nerve sheath tumors to MEK inhibitors
Molecular medicine (Cambridge, Mass.)
2025-09-30
Cina Aghamohammadi,Chandramouli Chandrasekaran,Tatiana A Engel
A doubly stochastic renewal framework for partitioning spiking variability
Nature communications
2025-09-30
Chandrashekhar Prasad,Rachel Griffard,Dong Pei,Steven Haworth,Navneet K Dhillon,Mario Castro,Isaac…
Extracellular Vesicle miRNAs as Biomarkers of Asthma Severity
Allergy
2025-09-30
Jose G Godoy-Lugo,Khristina E Young,Prerana Vaddi,Yvann Batamack,Jolaiya Aldridge,Sun Ok Fernandez…
Low protein-induced-FGF-21 signaling remodels adipose tissue on reduced markers of senescence during aging
GeroScience
2025-09-30
Elizabeth G Graham-Gurysh,Ryan N Woodring,Sean R Simpson,Sophie E Mendell,Nicole Rose Lukesh,Erik S…
Post-resection delivery of a TLR7/8 agonist from a biodegradable scaffold achieves immune-mediated glioblastoma clearance and protection against tumor challenge in mice
Nature communications
2025-09-29
Lubna Shawar,Gordon D Love,Benjamin T Uveges,J Alex Zumberge,Paco Cárdenas,José-Luis Giner,Roger E…
Chemical characterization of C31 sterols from sponges and Neoproterozoic fossil sterane counterparts
Proceedings of the National Academy of Sciences of the United States of America
2025-09-29
Jessica Weiselberg,Meng Niu,Cristian A Hernandez,Howard S Fox,Tina M Calderon,Joan W Berman
Methamphetamine Induces Metallothionein 1 Expression and an Inflammatory Phenotype in Primary Human HIV-Infected Macrophages
International journal of molecular sciences
2025-09-27
Keyao Chen,Ahmet Toksoz,Colin Henchy,Jessica Knapp,Jie Lu,Sarangarajan Ranganathan,Huabo Wang…
Derivation of Genetically Defined Murine Hepatoblastoma Cell Lines with Angiogenic Potential
Cancers
2025-09-27
Qiqige Wuyun,Quancheng Liu,Wentao Ni,Chunxiang Peng,Ziying Zhang,Xiaogen Zhou,Gang Hu,Lydia…
Alternative Conformation Prediction Using Deep Learning With Multi-MSA Strategy and Structural Clustering in CASP16
Proteins
2025-09-27
Justin Kauffman,Emma Holmes,Akhil Vaid,Alexander W Charney,Patricia Kovatch,Joshua Lampert,Ankit…
InfEHR: Clinical phenotype resolution through deep geometric learning on electronic health records
Nature communications
2025-09-26
Sadia Sinty Disha,Thushani I Punchipatabendi,Joseph D Kaszubowski,Biqing Liang,Janice D Pata…
Residues in the little finger domain of the Y-family Dpo4 DNA polymerase communicate to restrict synthesis past 8-oxoguanine lesions
Nucleic acids research
2025-09-26
Peter Kochunov,Si Gao,Lauren Salminen,Neda Jahanshad,Talia Nir,Paul Thompson,Xiaoming Du,Bhim…
Alzheimer's Disease-Like Brain Pattern Biomarker: Capturing Risks and Predicting Disease Onset
Research square
2025-09-26
Franziska Maria Mueller,Albert Leopold Müller,Wenyu Gu,Farshad Abdollah-Nia,Jiawei Sun,Jenna Kim…
Non-canonical resource allocation in heterotrophically growing Thermoanaerobacter kivui
Nature communications
2025-09-26
Mustapha Major,Paul Pham,Efrain Hernandez-Alvarez,Euiseok J Kim
Distinct neurogenic dynamics of cortico-cortical neuronal subtypes in layer 2/3 of the mouse visual cortex
Frontiers in neuroscience
2025-09-26
Mahmud Omar,Reem Agbareia,Donald U Apakama,Carol R Horowitz,Robert Freeman,Alexander W Charney…
New Model, Old Risks? Sociodemographic Bias and Adversarial Hallucinations Vulnerability in GPT-5
medRxiv : the preprint server for health sciences
2025-09-26
Bao V Nguyen,Can Özden,Kairong Dong,Oguz Can Koc,Ana P Torres-Ocampo,Noelle Dziedzic,Daniel…
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation
Nature communications
2025-09-26
Zhonghao Zhang,Ming Lu,Hao Liang,Zhongliang Zu,Yi Gu,Xiao Wang,Yuankai Huo,John C Gore,Xinqiang Yan
Fast Electromagnetic and RF Circuit Co-Simulation for Passive Resonator Field Calculation and Optimization in MRI
ArXiv
2025-09-26
Anindita Nayak,Digant Nayak,Lijia Jia,Eliza A Ruben,Suryavathi Viswanadhapalli,Priscila Dos Santos…
Cryo-EM structures reveal the molecular mechanism of SUMO E1-E2 thioester transfer
Nature structural & molecular biology
2025-09-25
Payam A Fathi,Michelle B Bales,Pranav Sathu,Julio E Ayala
Time-Restricted Access to High-Fat Diet Influences Weight Gain, Meal Patterns, and Food Preference
Obesity (Silver Spring, Md.)
2025-09-25
Fanhua Guo,Chenyang Zhao,Qinyang Shou,Ning Jin,Kay Jann,Xingfeng Shao,Danny Jj Wang
Assessing cerebral microvascular volumetric with high-resolution 4D cerebral blood volume MRI at 7 T
Nature cardiovascular research
2025-09-25
Jennifer Snoozy,Sushila Bhattacharya,Brandon Johnson,Robin R Fettig,Ashley Van Asma,Chloe Brede…
XDH-1 inactivation causes xanthine stone formation in Caenorhabditis elegans which is inhibited by SULP-4-mediated anion exchange in the excretory cell
PLoS biology
2025-09-24
Shahzada Khan,Jeremy Lum,Heather Stephenson,Pawan Bir Kohli,David Mortenson,Dhivya Ramakrishnan…
A highly selective TCR-mimic antibody reveals unexpected mechanisms of HBV peptide-MHC recognition and previously unknown target biology
mAbs
2025-09-24
Yun Zhang,Maor Sauler,David B Corry,Scott A Ochsner,Sarah Perusich,Li-Zhen Song,Joshua Malo,Raul…
Lung NR3C1+ and CXCR6high T cells distinguish immunopathogenesis of human emphysema
Communications biology
2025-09-24
Sergio Osorio,Jasmine Tan,Grace Levine,Seppo P Ahlfors,Steven Graham,Fahimeh Mamashli,Sheraz Khan…
Lower Cortical Activation and Altered Functional Connectivity Characterize Passive Auditory Spatial Attention in ASD
Autism research : official journal of the International Society for Autism Research
2025-09-24
Kaimin Jia,Helen Sun,Quang Kim Huynh,Dunya Al Marzooqi,Yongle Du,Yiyan Zhou,Wenjun Zhang
Discovery of Isonitrile Lipopeptide Chalkophores from Pathogenic Mycobacteria
Journal of natural products
2025-09-23
Yi Cheng Kang,Dmitriy M Volochnyuk,Serhiy V Ryabukhin,John F Hartwig
Late-Stage Oxidation of C(sp3 )─H Bonds with High Efficiency and Alkyl Group Dihydroxylation of Complex Molecules
Angewandte Chemie (International ed. in English)
2025-09-23
Bryce A Manso,Paloma Medina,Stephanie Smith-Berdan,Alessandra Rodriguez Y Baena,Elmira Bachinsky…
A Rare Hematopoietic Stem Cell-Derived Megakaryocyte Progenitor Accumulates via Enhanced Survival and Contributes to Exacerbated Thrombopoiesis Upon Aging
Aging cell
2025-09-23
Rajan Sawhney,Barbra D Ferrell,Thibaut Dejean,Zachary Schreiber,William Harrigan,Shawn W Polson,K…
Fine-tuning protein language models unlocks the potential of underrepresented viral proteomes
PeerJ
2025-09-23
Kun Zhao,Cheng-Chieh Hsu,Yash Pershad,Caitlyn Vlasschaert,Robert W Corty,Nan Wang,Jonathan Brett…
Interleukin-17 receptor-A signalling: atheroprotective role in JAK2 clonal haematopoiesis
European heart journal
2025-09-23
Chengbo Chen,Klaus N Lovendahl,Julie M Overbaugh,Kelly K Lee
Interprotomer crosstalk in mosaic viral glycoprotein trimers provides insight into polyvalent immunogen co-assembly
PLoS pathogens
2025-09-22
Morgan T Busboom,Kimberley Scott,Brad Corr,Katie L Bemis,Liana S Chinen,Sarah E Baker,Yasra Arif…
Anterior cingulate and its role in enhancing gait training outcomes in persons with cerebral palsy
Cerebral cortex (New York, N.Y. : 1991)
2025-09-22
Odalys Torné,Jacob P Nilles,Andrew L Smith,Kevin C Snyder,Kazuya Oikawa,Julie A Kiland,Mary R Telle…
Imaging Canine Post-Trabecular Aqueous Outflow Pathways: Effect of Acute Intraocular Pressure Elevation in Normal Eyes
Veterinary ophthalmology
2025-09-22
Rachel M Bennett,Kaitlyn C Housel,Tiffanie K Jones,Heather M Giannini,Gulus Emre,Mika Esperanza…
Two Physiologic Latent Classes of Acute Hypoxemic Respiratory Failure in Sepsis Are Distinguished by Lung Mechanics and Gas Exchange
Critical care explorations
2025-09-22
Ning Yang,Ali Abbaspour,James M Considine,Stephanie M McGregor,Erin G Brooks,Alexandra Naba,Kristyn…
Fibronectin composition and transglutaminase 2 cross-linking cooperatively regulate ovarian cancer cell adhesion in ECM-mimetic constructs
Acta biomaterialia
2025-09-20
Elena G Govorunova,Oleg A Sineshchekov,Hai Li,Yueyang Gou,Hongmei Chen,Shuyuan Yang,Yumei Wang…
Blue-shifted ancyromonad channelrhodopsins for multiplex optogenetics
eLife
2025-09-19
Tong Xiao,Dan He,Danqian Liu,Shang Jia,Qingyi Chen,Daniel Silverman,Neilabjo Maitra,Alan Y Huang…
RAD23B acquires a copper metalloadaptor function in amphibian-to-reptile evolution to increase metabolism and regulate genomic integrity
Molecular cell
2025-09-19
Sarah C Stanhope,Kratika Singhal,Nicolás M Morato,Yunfei Feng,Gaoya Meng,Makayla N Marlin,Claudia C…
Drosophila Ahcy is a redox sensor that modulates gene expression to protect against light stress-induced retinal degeneration
Proceedings of the National Academy of Sciences of the United States of America
2025-09-19
Ty Easley,Kevin Freese,Elizabeth Munch,Janine Bijsterbosch
Using topological data analysis to compare inter-subject variability across resting state functional MRI brain representations
ArXiv
2025-09-18
Khristian E Bauer-Rowe,Benjamin Pham,Michelle Griffin,Norah E Liang,Alexia Kim,John M Lu,Michael…
Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn's disease strictures
Cell
2025-09-18
Rob Knight,M Omar Din,Rodolfo Salido,Gillian Wright,Caitriona Brennan,Madison Ambre,Lauren Hansen…
Versatile wastewater monitoring of pathogens and antimicrobial resistance enabled by metatranscriptomics and long-read metagenomics
Research square
2025-09-18
Ming Lu,Xiaoyue Yang,Jason Moore,Pingping Li,Adam W Anderson,John C Gore,Seth A Smith,Xinqiang Yan
Low-Cost and Detunable Wireless Resonator Glasses for Enhanced Eye MRI with Concurrent High-Quality Whole-Brain MRI
ArXiv
2025-09-18
Xuejing Liu,Anyuan He,Dongliang Lu,Donghua Hu,Min Tan,Abenezer Abere,Parniyan Goodarzi,Bilal Ahmad…
Peroxisomal metabolism of branched fatty acids regulates energy homeostasis
Nature
2025-09-17
Bum Jin Kim,Marie Biondi Ryan,David C Dallas
Ultraviolet-C Treatment Better Preserves the Proteomic Profile of Donor Human Milk than Holder Pasteurization
Journal of agricultural and food chemistry
2025-09-17
Zhangxuan Hu,Sébastien Proulx,Grant A Hartung,Daniel E P Gomez,Jingyuan E Chen,Divya Varadarajan…
Visual stimulus-evoked blood velocity responses in individual human posterior cerebral arteries measured with dynamic phase-contrast functional MR angiography
Imaging neuroscience (Cambridge, Mass.)
2025-09-17
Dan L Pham,Dan Cappabianca,Matthew H Forsberg,Cole Weaver,Katherine P Mueller,Anna Tommasi,Jolanta…
Label-free metabolic imaging monitors the fitness of chimeric antigen receptor T cells
Nature biomedical engineering
2025-09-16
Peng Xu,Rubia Isler Mancuso,Marianna Leonzino,Caroline J Zeiss,Diane S Krause,Pietro De Camilli
Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C
PLoS biology
2025-09-16
Michael A Trebino,Giordan Kitts,James R J Haycocks,Rachel Wheat,Issac Chaudry,Jin Hwan Park,Ivan…
Parallel regulatory circuits orchestrate biofilm formation in response to c-di-GMP levels and growth phase
PLoS genetics
2025-09-15
Paramesha Bugga,Michael W Stoner,Janet R Manning,Bellina A S Mushala,Nisha Bhattarai,Maryam Sharifi…
GCN5L1 Inhibits Pyruvate Dehydrogenase Phosphorylation During Cardiac Ischemia-Reperfusion Injury
FASEB bioAdvances
2025-09-15
Austin Stellpflug,Amit Joshi,Shue Wang,Linxia Gu,Rongxue Wu,Bo Wang
Image-guided in vivo evaluation and comparison of bone-targeting peptides for therapeutic intervention
Drug delivery and translational research
2025-09-15
Aditi Singh,Jing Yang,Nicholas K Adzibolosu,Songchen Cai,Elana Kauf,Lingtao Yang,Qiyuan Li,Hanjie…
Decoding functional and developmental trajectories of tissue-resident uterine dendritic cells through integrative omics
iScience
2025-09-15
Ibrahim G Saleh,Marie Shimogawa,Jennifer Ramirez,Bernard Abakah,Yarra Venkatesh,Honey Priya James…
Genetic code expansion and enzymatic modifications as accessible methods for studying site-specific post-translational modifications of alpha-synuclein and tau
Protein science : a publication of the Protein Society
2025-09-13
Chinemerem P Ogbu,Nicolas Manuel Goldbach,Martin Pacesa,Srajan Kapoor,Bruno E Correia,Alex J Vecchio
Structures of a synthetic antibody selected against and bound to the C-terminal domain of Clostridium perfringens enterotoxin
Protein science : a publication of the Protein Society
2025-09-13
Pirouz Ebadi,Caleb M Stratton,Shaun K Olsen
E3 ubiquitin ligases in signaling, disease, and therapeutics
Trends in biochemical sciences
2025-09-12
Cameron J Glasscock,Robert J Pecoraro,Ryan McHugh,Lindsey A Doyle,Wei Chen,Olivier Boivin,Beau…
Computational design of sequence-specific DNA-binding proteins
Nature structural & molecular biology
2025-09-12
Philipp Flury,Jyoti Vishwakarma,Katharina Sylvester,Nobuyo Higashi-Kuwata,Agnieszka K Dabrowska…
Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity
Journal of medicinal chemistry
2025-09-11
Nicholas W Ringelberg,Renée E Mayfield,Julia S Lord,Graham H Diering,Alain C Burette,Benjamin D…
Cell Type-Specific Contributions of UBE3A to Angelman Syndrome Behavioral Phenotypes
eNeuro
2025-09-11
Yeon-Suk Yang,Mi-Jeong Kim,Sachin Chaugule,Emma Mayer,Ngoc DeSouza,Hong Ma,Jun Xie,Ki-Young Lee…
Nature-inspired IL-1 targeted therapy to treat chronic inflammatory diseases
Molecular therapy : the journal of the American Society of Gene Therapy
2025-09-11
Greana Kirubakar,Luana Johnston,Bom Nae Rin Lee,David G Russell,Nelson V Simwela
Incorporation of macrophage immune stresses into an intracellular assay of drug tolerance in Mycobacterium tuberculosis
Antimicrobial agents and chemotherapy
2025-09-11
Tzu-Lin Cheng,Feixuan Wu,Md Ezazul Haque,Abigail R Thiel,Danqing Wang,Jeffrey J Helgager,Lingjun Li…
Overexpression of ATase1 and ATase2 disrupts the secretome and causes a progeria phenotype
Life science alliance
2025-09-10