Omar Arias-Gaguancela,Carmen Palii,Mehar Un Nissa,Marjorie Brand,Jeffrey Ranish
QuickProt: A Bioinformatics and Visualization Tool for DIA and PRM Mass Spectrometry-Based Proteomics Datasets
Proteomics
2025-09-05
Brittany Rachelle Reynolds,Sean Raph,Anand Ramalingam,Shweta Srivastava,Pawel Lorkiewicz,Lillian E…
Don't Go Vaping My Heart: E-cigarette Exposure During Pregnancy Promotes Peripartum Ventricular Arrhythmias and Sympathetic Dominance
American journal of physiology. Heart and circulatory physiology
2025-09-04
Andres Chang,Adam N Pelletier,Donald J McGuire,Maria Tsagiopoulou,Maria Karipidou,Amy Ayers,Alyssa…
PD-1 expression identifies proliferating malignant CLL B cells and is a potential biomarker of response to BTK inhibitor therapy
Proceedings of the National Academy of Sciences of the United States of America
2025-09-04
Vanessa L Ehlers,Anvitha Sriram,Bradey A R Stuart,Christina M Mecca,Cheryl L Stucky
Sensory neuron PIEZO1 deletion inhibits dynamic light touch sensitivity in uninjured mice, prevents neuropathic light touch hypersensitivity, and drives compensatory changes in dorsal root ganglia
Pain
2025-09-02
Christopher J Bowman,Dorothea M Stibor,Xiaofei Sun,Nika Lenci,Hiromichi Shimizu,Emily F Yamashita…
A20's linear ubiquitin-binding motif restrains pathogenic activation of Th17 cells and IL-22-driven enteritis
The Journal of clinical investigation
2025-09-02
Zhong Chen,Lijuan Song,Wanqiu Chen,Charles Wang
Single-cell profiling of H3K4me1-H3K27me3 revealed bivalent regulation of abnormal neuronal development caused by prenatal e-cigarette vaporing
Communications biology
2025-09-01
Jeanine G Gezelle,Sophie M Korn,Jayden T McDonald,Zhen Gong,Anna Erickson,Chih-Hung Huang,Feiyue…
A conserved viral RNA fold enables nuclease resistance across kingdoms of life
Nucleic acids research
2025-08-30
Layla Banihashemi,Yicheng Zhang,Alison E Hipwell,Mary L Phillips
The promise of infant MRI in psychiatry: toward a framework for neural network measures in early emotional and behavioral risk identification and new intervention targets
Molecular psychiatry
2025-08-30
Deling He,Lingfeng Xu,Tobey Betthauser,Carol Van Hulle,Julie Liss,Visar Berisha,Kimberly Mueller
Automated bimodal pause analysis for acoustic markers of cognitive decline and Alzheimer's disease in connected speech
Alzheimer's & dementia : the journal of the Alzheimer's Association
2025-08-30
John G Ricca,Holly A Petersen,Adam Grosvirt-Dramen,Xavier Mayali,Sarah H Naylon,Bobby G Duersch…
A family of tubular pili from harmful algal bloom forming cyanobacterium Microcystis aeruginosa
Nature communications
2025-08-29
Kevin Sung,Mackenzie M Johnson,Will Dumm,Noah Simon,Hugh Haddox,Julia Fukuyama,Frederick A Matsen
Thrifty wide-context models of B cell receptor somatic hypermutation
eLife
2025-08-29
Niyada Hin,Chae Bin Lee,Sadakatali Gori,Barbara S Slusher,Rana Rais,Takashi Tsukamoto
Prodrugs 2-(Phosphonomethyl)pentanedioic Acid (2-PMPA) as Orally Available Glutamate Carboxypeptidase II Inhibitors
ACS medicinal chemistry letters
2025-08-29
Ziyan Liang,Aakaanksha Maddineni,Jesus A Ortega,Christine B Magdongon,Shreya Jambardi,Subrata Roy…
Cytotoxicity of activator expression in CRISPR-based transcriptional activation systems
Nature communications
2025-08-28
Sarah A Tripplehorn,Santana M Lardo,Margaret K Shirra,Hannah G Marvil,Sarah J Hainer,Karen M Arndt
A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes
Nucleic acids research
2025-08-28
Maryam H Alsameen,Felicha T Candelaria-Cook,Cassandra M Cerros,Dina E Hill,Julia M Stephen
Altered neuronal network connectivity in children with fetal alcohol spectrum disorder and its association with inhibitory function
Alcohol, clinical & experimental research
2025-08-28
Mona Gebril,Sparhawk Mulder,Rimi Das,Shanmugasundaram Nallasamy
Extracellular matrix reorganization during endometrial decidualization
Histochemistry and cell biology
2025-08-28
Lilian Cruz,Frederico Moraes Ferreira,Camila Miranda Lopes-Ramos,Zhiyun Wei,William T Hendriks,H A…
Intracellular and Extracellular Vesicle miRNA Signatures in Human iPSC-Derived Neural Stem Cells and Floor Plate Progenitors
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2025-08-28
Anna Clapp Organski,Anjali Reddivari,Lavanya Reddivari,Douglas K Brubaker,Kelly N Z Fuller,John P…
Oral Contraceptives Induce Time- and Intestinal Segment-Dependent Shifts in the Gut Microbiota
Nutrients
2025-08-28
Mollie K Huber,Adrienne E Widener,Alexandra E Cuaycal,Dylan Smurlick,Elizabeth A Butterworth…
Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis
Cell reports
2025-08-28
Bingbing Duan,Chenxi Qiu,Sing-Hoi Sze,Craig Kaplan
Widespread epistasis shapes RNA polymerase II active site function and evolution
Nature communications
2025-08-27
Celia Fernandez-Sanz,Sergio De la Fuente,Zuzana Nichtova,Marilen Federico,Stephane Duvezin-Caubet…
Highly Oligomeric DRP1 Strategic Positioning at Mitochondria-Sarcoplasmic Reticulum Contacts in Adult Murine Heart Through ACTIN Anchoring
Cells
2025-08-27
Kwok-Ho Lam,Linfeng Gao,Adina Przykopanski,Baohua Chen,Ting Huang,Maren Krüger,Anna-Magdalena…
A nut-and-bolt assembly of the bimodular large progenitor botulinum neurotoxin complex
Science advances
2025-08-27
Céline Dorval,Adrian D Matthews,Karina Targos,Sara N Alektiar,Dylan E Holst,Zhifeng Tan,Mikko…
Unlocking azole chemical space via modular and regioselective N-alkylation
Nature chemistry
2025-08-26
Sara M Fielder,Marisa W Friederich,Daniella H Hock,Jessie R Zhang,Liana M Valin,Jill A Rosenfeld…
Dominant negative ATP5F1A variants disrupt oxidative phosphorylation causing neurological disorders
EMBO molecular medicine
2025-08-26
Dhanya Thamaraparambil Jayaram,Pranav Sivaram,Pranjal Biswas,Yue Dai,Elizabeth A Sweeny,Dennis J…
Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH
Nature communications
2025-08-26
Yuchen He,Benjamin M Faulkner,Rachel S Weatherford,Emily Hyun,Cliff I Stains
Split-Small GTPase Reassembly as a Method to Control Cellular Signaling with User-Defined Inputs
ACS chemical biology
2025-08-26
Adam Seluzicki,Joanne Chory
Genetic architecture of a light-temperature coincidence detector
Nature communications
2025-08-26
Bruna Favetta,Huan Wang,Jasmine Cubuk,Arjun Singh,Mayur Barai,Cesar Ramirez,Haiyan Zheng,Adam J…
Phosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states
Nature communications
2025-08-26
Ruth M Shontell,David Araki,Kendra M Ormsbee,Donovan D Delgado,Robert A Nichols
The Beta Amyloid Core Hexapeptide Protects Against Full-Length Beta Amyloid-Induced Alteration of Dendritic Spine Morphology and Density
eNeuro
2025-08-25
Jun Yang,Yusheng Yang,Huizhe Wang,Steven H Liang,Chongzhao Ran
Molecular Afterglow of Lophine-Based Luminophore and Its Imaging Applications
Angewandte Chemie (International ed. in English)
2025-08-25
Kayleigh M Voos,Joyce Tzeng,Priya Patel,Sophie Rubinsky,Ha E Choi,Trevor Pharr,Sebastian Sookram…
Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity
Nature communications
2025-08-25
Sarah J Harmych,Thomas P Hasaka,Chelsie K Sievers,Seung Woo Kang,Marisol A Ramirez,Vivian Truong…
3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer
Communications biology
2025-08-23
Alexander Biederstädt,Rafet Basar,Jeong-Min Park,Nadima Uprety,Rejeena Shrestha,Francia Reyes Silva…
Genome-wide CRISPR screens identify critical targets to enhance CAR-NK cell antitumor potency
Cancer cell
2025-08-22
Amber M Smith,Yang Li,Arianna Velarde,Yifan Cheng,Alan D Frankel
The HIV-1 nuclear export complex reveals the role of RNA in CRM1 cargo recognition
Molecular cell
2025-08-22
Aria Zheyuan Huang,Louis S Prahl,Karen Xu,Robert L Mauck,Jason A Burdick,Alex J Hughes
Engineering kidney developmental trajectory using culture boundary conditions
Nature communications
2025-08-22
Serafina G Lopez,John Dankert,James J Butler,John G Kennedy,Lawrence J Bonassar,Rebecca M Irwin
Medial Osteochondral Defect Drives Matrix and Cell Pathology in Compartment-Matched Meniscus
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2025-08-22
Macy Mora-Antoinette,Andrea Garcia-Ortiz,Mariam Obaji,Alexander Saffari,Melia D Matthews,Murtaza…
Cholinergic regulation of osteocyte mechanobiology: A paradigm for bone adaptation
Science advances
2025-08-22
M Esad Gunes,Satyajit Patwardhan,Sarah Merl,Kryscilla Yang,Rebecca Jones,Bryan Chen,Elin Manell…
MHC Class II Sharing Appears to Promote Intestinal Allograft Tolerance Through Linked Suppression in a Large Animal Model
Transplantation
2025-08-21
Md Nure Alam,Luke Marney,Liping Yang,Jaewoo Choi,Natasha Cerruti,Natascha Techen,Samuel Bassett…
Clustering of chemical profiles of Centella asiatica cultivars, grown in greenhouses, allows grouping of metabolites with similar production trends
Industrial crops and products
2025-08-21
Hannah Y Collins,Ryan A Doan,Jiaxing Li,Jason E Early,Megan E Madden,Tyrell Simkins,David A Lyons…
FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system
Nature communications
2025-08-21
Zidong Yang,Fanhua Guo,Steve Mendoza,Ziyang Huang,Yingying Li,Yunqing Ying,Xin Cheng,Qi Yang…
Assessment of Small Vessel Density Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalophy (CADASIL) by High-Resolution Black-Blood MRI
Journal of magnetic resonance imaging : JMRI
2025-08-21
Elena Molokanova,Teng Zhou,Pragna Vasupal,Volodymyr P Cherkas,Prashant Narute,Mariana S A Ferraz…
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics
Nature communications
2025-08-20
Duncan K Ralph,Athanasios G Bakis,Jared Galloway,Ashni A Vora,Tatsuya Araki,Gabriel D Victora,Yun S…
Inference of germinal center evolutionary dynamics via simulation-based deep learning
ArXiv
2025-08-20
Lanuza A P Faccioli,Yiyue Sun,Olamide Animasahun,Takashi Motomura,Zhenghao Liu,Takeshi Kurihara…
Human-induced pluripotent stem cell-based hepatic modeling of lipid metabolism-associated TM6SF2-E167K variant
Hepatology (Baltimore, Md.)
2025-08-20
Anna Goodheart,Chi-Hyeon Yoo,Aline Fassini,Tewodros Dagnew,Rong Ye,Robin Striar,Moqing Quan,Anna…
Imaging brain class I histone deacetylase changes in the Lewy body dementias and Parkinson's disease
Research square
2025-08-20
Ricardo Rivero,Vaneza Tique-Salleg,Daniel Echeverri-De la Hoz,Lambodhar Damodaran,Daniela Paternina…
Genomic epidemiology of dengue virus 2 and 3 reveals repeated introductions and exportations of several lineages in Colombia
medRxiv : the preprint server for health sciences
2025-08-20
Marilena Tauro,Tao Li,Praneeth R Sudalagunta,Mark Meads,Rafael Renatino Canevarolo,Niveditha…
Unc-51 Like Kinase 3 (ULK3) is essential for autophagy and cell survival in multiple myeloma
Research square
2025-08-20
Andrew T Kosharek,Cindy L Zuleger,William S Glass,Jens Eickhoff,Paul M Sondel,David M Vail,Mark R…
In vitro detection of canine anti-human antibodies following intratumoral injection of the hu14.18-IL2 immunocytokine in spontaneous canine melanoma
PloS one
2025-08-19
Fang Li,Elise Flynn,Philip Ha,Mazal N Zebak,Haoxiang Cheng,Chenyi Xue,Jianting Shi,Xun Wu,Ziyi Wang…
LIPA, a risk locus for coronary artery disease: decoding the variant-to-function relationship
European heart journal
2025-08-19
Gaurav Sharma,Bankala Krishnarjuna,Volodymyr M Hiiuk,Magdalena I Ivanova,Pavel Nagorny,Ayyalusamy…
Detergent-free isolation and characterization of amyloid precursor protein C99 in E. coli native lipid-nanodiscs using non-ionic polymer
Protein science : a publication of the Protein Society
2025-08-19
McKenna Loop Yao,Nicholas A Zill,Colin Charles Barber,Yongle Du,Peijun Lin,Rui Zhai,Eunice Yoon…
Synergistic action of specialized metabolites from divergent biosynthesis in the human oral microbiome
Proceedings of the National Academy of Sciences of the United States of America
2025-08-19
Lianxia Li,Unimunkh Uriyanghai,Christine Wai,Hong Yuan,Eric W Livingston,Edward M Bahnson,Vinay…
Temporal evolution of hemodynamics in murine arteriovenous fistula: A micro-CT based CFD study
PLoS computational biology
2025-08-18
Taame G Seyoum,Zhenming Du,Siming Wang,Wen Lu,Qiyue Mao,Xiaoxiao Yang,Aman Dekebo,Ermias Dagne…
New Tirucallane-Type Triterpenes Isolated from from Ethiopia with Anticancer Activity
ACS omega
2025-08-18
Theresa Wechsler,Ryuta Asada,Andrew N M Dominguez,Rachel Montpetit,Julia K McCormick,Kalyn…
A time-resolved framework for the recruitment of mRNP processing and assembly factors to a site of transcription
Nucleic acids research
2025-08-18
Heather Learnard,Jason Core,Heather Corkrey,Anthony Sciaudone,Jeffrey Rade,Hardy Kornfeld,Jennifer…
Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19
PLoS pathogens
2025-08-18
Nathaniel P Skillin,Lorin Danielsen,Bruce E Kirkpatrick,Jonathan D Hoang,Lea Pearl Hibbard,Kristi S…
Anisotropic liquid crystalline hydrogels direct 2D and 3D myoblast alignment
Advanced functional materials
2025-08-18
Raela B Ridley,Brianna M Tischner,Jieun Lee,Erin Walsh,Michael T Massengill,Alfred S Lewin…
Modulation of retinal inflammation delays degeneration in a mouse model of geographic atrophy
Scientific reports
2025-08-17
Cecilia A Westbrook,Michael Schlund,Jennifer S Silk,Erika E Forbes,Neal D Ryan,Ronald E Dahl,Dana L…
The role of reward-related brain activity in response to treatment and later depression severity: data from a randomized controlled trial in early adolescents with anxiety disorders
Translational psychiatry
2025-08-16
Xiangsheng Zuo,Yoshiyuki Kiyasu,Yi Liu,Yasunori Deguchi,Fuyao Liu,Micheline Moussalli,Lin Tan,Bo…
Colorectal ALOX15 as a host factor determining the effects of EPA and DHA on colorectal tumorigenesis in mice
Cellular and molecular gastroenterology and hepatology
2025-08-16
Dowlette-Mary Alam El Din,Leah Moenkemoeller,Alon Loeffler,Forough Habibollahi,Jack Schenkman…
Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory
Communications biology
2025-08-16
Hayden S Saunders,Un Seng Chio,Camille M Moore,Vijay Ramani,Yifan Cheng,Geeta J Narlikar
HMGB1 deforms nucleosomal DNA to generate a dynamic chromatin environment counteracting the effects of linker histone
Science advances
2025-08-15
Katherine M Bever,Sarah M Shin,Jennifer N Durham,Hanfei Qi,Alexei Hernandez,Erin M Coyne,Nicole E…
A phase 2 trial of CXCR4 antagonism and PD1 inhibition in metastatic pancreatic adenocarcinoma reveals recruitment of T cells but also immunosuppressive macrophages
Oncoimmunology
2025-08-15
Thomas H Ambrosi,David Morales,Kun Chen,Ethan J Hunt,Kelly C Weldon,Amber N Maifeld,Fatima I M…
Basigin links altered skeletal stem cell lineage dynamics with glucocorticoid-induced bone loss and impaired angiogenesis
Nature communications
2025-08-15
Chun-Feng David Hou,Nathan Bellis,Ravi K Lokareddy,Steven Branston,Johnny Reid,Renae Geier,Angela…
High-resolution Cryo-EM Analysis of the Therapeutic Pseudomonas Phage Pa223
Journal of molecular biology
2025-08-14
Hsin-Ju Chan,Boris Krichel,Liam J Bandura,Emily A Chapman,Holden T Rogers,Matthew S Fischer,David S…
Structural Heterogeneity of Proteoform-Ligand Complexes in Adenosine Monophosphate-Activated Protein Kinase Uncovered by Integrated Top-Down Mass Spectrometry
Journal of the American Chemical Society
2025-08-14
Carmen I Bango,Scott A Jones,Sara Shao,Dani Y Del Rubin,Arturo Lopez Flores,Bonnie J Nagel,Amy L…
Associations between pain experiences and gray matter volume in youth in the adolescent brain cognitive development (ABCD) study
The journal of pain
2025-08-14
Yiwei Zhang,Shuvendu Saha,Yesen Cheng,Yannik C C Esser,Chi P Ting
Catalytic Markovnikov Hydrothiolation of Dehydroamino Acids: Unified Total Synthesis of Enteropeptin Sactipeptides
Journal of the American Chemical Society
2025-08-14
Zoe Quandt,Arabella Young,Graham Larson Barlow,Jennifer A Smith,Irina Kusmartseva,Shen Dong,Melanie…
Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas
Journal for immunotherapy of cancer
2025-08-14
Josepha C Sedzro,Amanda L Photenhauer,Fabienne Birkle,Katarina Meze,Alex Mortenson,Cade Duckworth…
Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism
Blood
2025-08-14
Zeng Rong Wong,Binh Khanh Mai,Willi R Berg,Alexander Kvitsinski,Thor L F Correia,Yu Zhang,Peng Liu…
Reactions of Difluorocarbene with Organogold(I) Complexes: Synthesis of Gem-Difluoromethylene Organometallics via Difluorocarbene Insertion and Cycloaddition Reactions
Angewandte Chemie (International ed. in English)
2025-08-14
Steven B Wells,Daniel B Rainbow,Michal Mark,Peter A Szabo,Can Ergen,Daniel P Caron,Ana Raquel…
Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age
Nature immunology
2025-08-13
Gaoyuan Lu,Shuling Xu,Penghsuan Huang,Lingjun Li
Enhancing Lipidomics With High-Resolution Ion Mobility-Mass Spectrometry
Proteomics
2025-08-13
Tatyana Appelbaum,David A Smith,Kei Takahashi,Jennifer C Kwok,Hannah Sorenson,William A Beltran
Impact of PEGylation and hyaluronan functionalization on lipoplex-mediated mRNA delivery to the canine retina
Drug delivery
2025-08-13
Clare Moffatt,Pranati Pillutla,Israa A Laklouk,Alden F Smith,Dinesh K Chhetri
Radiation Fibrosis of the Epiglottis: Histopathology and Multiphoton Imaging of Collagen and Elastin
The Laryngoscope
2025-08-13
Arabo A Avanes,Hunter T Warren,Abinaya Senthil,David E Olson
Pharmacological Evaluation of Tropane Analogues at the Serotonin Transporter
ACS chemical neuroscience
2025-08-13
Kay Jann,Gilsoon Park,John M Ringman,Hosung Kim
Classifying mild cognitive impairment from normal cognition: fMRI complexity matches tau PET performance
Alzheimer's & dementia (Amsterdam, Netherlands)
2025-08-13
Jonathan Kuhn,Parijat Banerjee,Andrew Haye,Douglas N Robinson,Pablo A Iglesias,Peter N Devreotes
Complementary cytoskeletal feedback loops control signal transduction excitability and cell polarity
Nature communications
2025-08-12
Sarah Frail,Melissa Steele-Ogus,Jon Doenier,Solène L Y Moulin,Tom Braukmann,Shouling Xu,Ellen Yeh
Genomes of nitrogen-fixing eukaryotes reveal an alternate path for organellogenesis
Proceedings of the National Academy of Sciences of the United States of America
2025-08-12
Yu Zhu,Kevin F Brulois,Thanh T Dinh,Junliang Pan,Eugene C Butcher
COUP-TFII-mediated reprogramming of the vascular endothelium counteracts tumor immune evasion
Nature communications
2025-08-12
Jonathan Nover,Matthew Bai,Prem Tismina,Ganesh Raut,Dhavalkumar Patel,Girish N Nadkarni,Benjamin S…
Comparing Machine Learning and Nurse Predictions for Hospital Admissions in a Multisite Emergency Care System
Mayo Clinic proceedings. Digital health
2025-08-12
Rebeca Arroyo Hornero,Raul A Maqueda-Alfaro,Miguel A Solís-Barbosa,Rebecca A Leylek,Olin Medina…
TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells
Nature immunology
2025-08-12
Amineh Rastandeh,Nino Makasarashvili,Herman K Dhaliwal,Sherry Baker,Sundharraman Subramanian,Daniel…
Measuring the selective packaging of RNA molecules by viral coat proteins in cells
Proceedings of the National Academy of Sciences of the United States of America
2025-08-11
Steven P Jones,Nathan O'Leary,Ernesto Pena Calderin,Richa Singhal,Jason Hellmann,Celio Damacena de…
Exercise sensitizes the pressure diuresis response: shifting immune landscapes may underlie renal adaptations
American journal of physiology. Renal physiology
2025-08-11
Eric W Bell,Benjamin P Brown,Jens Meiler
FakeRotLib: Expedient Noncanonical Amino Acid Parametrization in Rosetta
Journal of chemical information and modeling
2025-08-11
Yewei Wang,Jacqueline Holstein,Karen Hermetz,Amber Burt,Corina Lesseur,Parinya Panuwet,Nancy…
Prenatal pyrethroid exposure, placental gene network modules, and neonatal neurobehavior
International journal of hygiene and environmental health
2025-08-11