Junwoo Suh,Yehe Liu,Jordan Smith,Michiko Watanabe,Andrew M Rollins,Michael W Jenkins
A Simple and Fast Optical Clearing Method for Whole-Mount Fluorescence In Situ Hybridization (FISH) Imaging
Journal of biophotonics
2024-10-10
Colin R Coleman,Judit Pallos,Alicia Arreola-Bustos,Lu Wang,Daniel Raftery,Daniel E L Promislow,Ian…
Natural variation in age-related dopamine neuron degeneration is glutathione dependent and linked to life span
Proceedings of the National Academy of Sciences of the United States of America
2024-10-10
Ghislain Rocheleau,Shoa L Clarke,Gaëlle Auguste,Natalie R Hasbani,Alanna C Morrison,Adam S Heath…
Rare variant contribution to the heritability of coronary artery disease
Nature communications
2024-10-09
Sarah N Cilvik,Brit Boehmer,Stephanie R Wesolowski,Laura D Brown,Paul J Rozance
Chronic late gestation fetal hyperglucagonaemia results in lower insulin secretion, pancreatic mass, islet area and beta- and α-cell proliferation
The Journal of physiology
2024-10-09
Osman Sharifi,Viktoria Haghani,Kari E Neier,Keith J Fraga,Ian Korf,Sophia M Hakam,Gerald Quon…
Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progression
Communications biology
2024-10-09
Malik Zohaib Ali,Taru S Dutt,Amy MacNeill,Amanda Walz,Camron Pearce,Ha Lam,Jamie S Philp,Johnathan…
A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides
eLife
2024-10-08
Yaxian Zhou,Chunrong Li,Xuankun Chen,Yuan Zhao,Yaxian Liao,Penghsuan Huang,Wenxin Wu,Nicholas S…
Development of folate receptor targeting chimeras for cancer selective degradation of extracellular proteins
Nature communications
2024-10-08
Ilaria Baldassarri,Daniel Naveed Tavakol,Pamela L Graney,Alan G Chramiec,Hanina Hibshoosh,Gordana…
An engineered model of metastatic colonization of human bone marrow reveals breast cancer cell remodeling of the hematopoietic niche
Proceedings of the National Academy of Sciences of the United States of America
2024-10-07
Bradley W Biggs,Morgan N Price,Dexter Lai,Jasmine Escobedo,Yuridia Fortanel,Yolanda Y Huang…
High-throughput protein characterization by complementation using DNA barcoded fragment libraries
Molecular systems biology
2024-10-07
Andrew F Mead,Neil B Wood,Shane R Nelson,Bradley M Palmer,Lin Yang,Samantha Beck Previs,Angela…
Functional role of myosin-binding protein H in thick filaments of developing vertebrate fast-twitch skeletal muscle
The Journal of general physiology
2024-10-07
Stephen M Lander,Garth Fisher,Blake A Everett,Peter Tran,Arthur Prindle
Secreted nucleases reclaim extracellular DNA during biofilm development
NPJ biofilms and microbiomes
2024-10-07
Shristi Pawnikar,Brenda S Magenheimer,Keya Joshi,Ericka Nevarez-Munoz,Allan Haldane,Robin L Maser…
Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists
eLife
2024-10-07
Stephano M Iglesias,Chun-Feng David Hou,Johnny Reid,Evan Schauer,Renae Geier,Angela Soriaga,Lucy…
Cryo-EM analysis of Pseudomonas phage Pa193 structural components
Communications biology
2024-10-06
Samantha Bradford,Rohan Joshi,Shangbang Luo,Emily Farrah,Yilu Xie,Donald J Brown,Tibor Juhasz,James…
In Vivo Femtosecond Laser Machined Transepithelial Nonlinear Optical Corneal Crosslinking Compared to Ultraviolet Corneal Crosslinking
Translational vision science & technology
2024-10-04
Jake D Lehle,Yu-Huey Lin,Amanda Gomez,Laura Chavez,John R McCarrey
An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis
eLife
2024-10-03
Daniel C Stewart,Becky K Brisson,Bassil Dekky,Ashton C Berger,William Yen,Elizabeth A Mauldin…
Prognostic and therapeutic implications of tumor-restrictive type III collagen in the breast cancer microenvironment
NPJ breast cancer
2024-10-02
Arvin B Karbasi,Jaden D Barfuss,Theodore C Morgan,Daniel Collins,Drew A Costenbader,David G Dennis…
Sol-moiety: Discovery of a water-soluble prodrug technology for enhanced oral bioavailability of insoluble therapeutics
Nature communications
2024-10-01
Yun Hu,Sébastien Paris,Narayan Sahoo,Qi Wang,Qianxia Wang,Hampartsoum B Barsoumian,Ailing Huang…
Superior antitumor immune response achieved with proton over photon immunoradiotherapy is amplified by the nanoradioenhancer NBTXR3
Journal of nanobiotechnology
2024-10-01
Ravi K Lokareddy,Chun-Feng David Hou,Francesca Forti,Stephano M Iglesias,Fenglin Li,Mikhail…
Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor
Nature communications
2024-10-01
Susan Kilgas,Aleem Syed,Patrick Toolan-Kerr,Michelle L Swift,Shrabasti Roychoudhury,Aniruddha…
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity
Nature communications
2024-09-30
Zhenwei Gong,Manisha Dixit,Zhiming He,Sher Bahadur Poudel,Gozde Yildirim,Shoshana Yakar,Radhika…
Deletion of absent in melanoma-2 (AIM2) drives bone marrow adipogenesis and impairs bone microarchitecture
GeroScience
2024-09-30
Megan L Ludwig,David Moline,Alec Horrmann,Ella Boytim,Gabrianne Larson,Ali T Arafa,Masooma Sayeda…
Integrated multi-omics assessment of lineage plasticity in a prostate cancer patient with brain and dural metastases
NPJ precision oncology
2024-09-30
Hector M Nieves-Rosado,Hridesh Banerjee,Angela Gocher-Demske,Priyanka Manandhar,Isha Mehta…
Tim-3 Is Required for Regulatory T Cell-Mediated Promotion of T Cell Exhaustion and Viral Persistence during Chronic Lymphocytic Choriomeningitis Virus Infection
Journal of immunology (Baltimore, Md. : 1950)
2024-09-30
Morgan C Finnerty,Franklin E Leach,Yousef Zakharia,Kenneth G Nepple,Michael G Bartlett,Michael D…
Identification of blood lipid markers of docetaxel treatment in prostate cancer patients
Scientific reports
2024-09-27
Sarah E Hickson,Jennifer L Hyde
RNA structures within Venezuelan equine encephalitis virus E1 alter macrophage replication fitness and contribute to viral emergence
PLoS pathogens
2024-09-27
Matthew J O'Neill,Tao Yang,Julie Laudeman,Maria E Calandranis,M Lorena Harvey,Joseph F Solus…
ParSE-seq: a calibrated multiplexed assay to facilitate the clinical classification of putative splice-altering variants
Nature communications
2024-09-27
Léa Ripoll,Yong Li,Carmen W Dessauer,Mark von Zastrow
Spatial organization of adenylyl cyclase and its impact on dopamine signaling in neurons
Nature communications
2024-09-27
Michelle M Martinez Irizarry,Julia R Walsh,Malgorzata M Kamocka,Hyowon Lee,Kenneth W Dunn
Longitudinal intravital microscopy of the mouse kidney: inflammatory responses to abdominal imaging windows
American journal of physiology. Renal physiology
2024-09-26
Zhangxuan Hu,Avery J L Berman,Zijing Dong,William A Grissom,Timothy G Reese,Lawrence L Wald,Fuyixue…
Reduced physiology-induced temporal instability achieved with variable-flip-angle fast low-angle excitation echo-planar technique with multishot echo planar time-resolved imaging
Magnetic resonance in medicine
2024-09-26
Michael J Neuhoff,Yuchen Wang,Nicholas J Vantangoli,Michael G Poirier,Carlos E Castro,Wolfgang G…
Recycling Materials for Sustainable DNA Origami Manufacturing
Nano letters
2024-09-24
Joshua K Marchant,Natalie G Ferris,Diana Grass,Magdelena S Allen,Vivek Gopalakrishnan,Mark Olchanyi…
Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging - A Symposium Review
Neuroinformatics
2024-09-23
Haiyan Lu,Zexin Zhu,Lauren Fields,Hua Zhang,Lingjun Li
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross-Linking
Mass spectrometry reviews
2024-09-20
Kyle I Mentkowski,Touba Tarvirdizadeh,Cody A Manzanero,Lisa A Eagler,Jennifer K Lang
Surface engineering enhances the therapeutic potential of systemically delivered extracellular vesicles following acute myocardial infarction
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2024-09-20
Xu Feng,Chang Yang,Yuanjian Huang,Dan Su,Chao Wang,Lori Lyn Wilson,Ling Yin,Mengfan Tang,Siting Li…
In vivo CRISPR screens identify Mga as an immunotherapy target in triple-negative breast cancer
Proceedings of the National Academy of Sciences of the United States of America
2024-09-19
Raveen Rathnasinghe,Lauren A Chang,Rebecca Pearl,Sonia Jangra,Amy Aspelund,Alaura Hoag,Soner Yildiz…
Sequential immunization with chimeric hemagglutinin ΔNS1 attenuated influenza vaccines induces broad humoral and cellular immunity
NPJ vaccines
2024-09-19
Hao Chen,Sohjeong Kim,Chi P Ting
Total Synthesis of (±)-3-Thiaglutamate
Tetrahedron letters
2024-09-19
Sarah B Worthan,Robert D P McCarthy,Mildred Delaleau,Ryan Stikeleather,Benjamin P Bratton,Marc…
Evolution of pH-sensitive transcription termination in Escherichia coli during adaptation to repeated long-term starvation
Proceedings of the National Academy of Sciences of the United States of America
2024-09-19
Hanxiao Zhang,Chenyu Zhou,Zarith Mohammad,Jianhua Zhao
Structural basis of human 20S proteasome biogenesis
Nature communications
2024-09-18
Stella E Cho,Wei Li,Andrew M Beard,Jonathan A Jackson,Risa Kiernan,Kazunori Hoshino,Adam C Martin…
Actomyosin contraction in the follicular epithelium provides the major mechanical force for follicle rupture during Drosophila ovulation
Proceedings of the National Academy of Sciences of the United States of America
2024-09-18
Cheryl A C Peretz,Vanessa E Kennedy,Anushka Walia,Cyrille L Delley,Andrew Koh,Elaine Tran,Iain C…
Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia
Nature communications
2024-09-18
M Esad Gunes,Daniel H Wolbrom,Emilie Ditlev Nygaard,Elin Manell,Philip Jordache,Susan Qudus…
OMIP-108: 22-color flow cytometry panel for detection and monitoring of chimerism and immune reconstitution in porcine-to-baboon models of operational xenotransplant tolerance studies
Cytometry. Part A : the journal of the International Society for Analytical Cytology
2024-09-18
Khanh V Doan,Timothy S Luongo,Thato T Ts'olo,Won Dong Lee,David W Frederick,Sarmistha…
Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics
Nature cardiovascular research
2024-09-18
Andrea Pierré,Tuan Pham,Jonah Pearl,Sandeep Robert Datta,Jason T Ritt,Alexander Fleischmann
A Perspective on Neuroscience Data Standardization with Neurodata Without Borders
The Journal of neuroscience : the official journal of the Society for Neuroscience
2024-09-18
Thomas C M Lavery,Carol A Rasmussen,Alexander W Katz,Charlene B Y Kim,James N Ver Hoeve,Paul E…
Development of Microcystoid Macular Degeneration in the Retina of Nonhuman Primates: Time-Course and Associated Pathologies
Current eye research
2024-09-18
Omar Jawdat,Jason Rucker,Tomoki Nakano,Kotaro Takeno,Jeffery Statland,Mamatha Pasnoor,Mazen M…
Resistance exercise in early-stage ALS patients, ALSFRS-R, Sickness Impact Profile ALS-19, and muscle transcriptome: a pilot study
Scientific reports
2024-09-17
Nancy Yanzhe Li,Weiruo Zhang,Daniel Haensel,Anna R Jussila,Cory Pan,Sadhana Gaddam,Sylvia K…
Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche
Nature communications
2024-09-17
Sourya Bhattacharyya,Ferhat Ay
Identifying genetic variants associated with chromatin looping and genome function
Nature communications
2024-09-17
Yuanqi Sun,Di Cao,Jay J Pillai,Adrian Paez,Yinghao Li,Chunming Gu,Jacob M Pogson,Linda Knutsson…
Rapid imaging of intravenous gadolinium-based contrast agent (GBCA) entering ventricular cerebrospinal fluid (CSF) through the choroid plexus in healthy human subjects
Fluids and barriers of the CNS
2024-09-16
Li-Ming Hsu,Yen-Yu Ian Shih
Neuromodulation in Small Animal fMRI
Journal of magnetic resonance imaging : JMRI
2024-09-16
Jianfeng Lin,Jian Miao,Katherine G Schaefer,Charles M Russell,Robert J Pyron,Fuming Zhang,Quynh T…
Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin
Nature microbiology
2024-09-16
Bradley P Clarke,Alexia E Angelos,Menghan Mei,Pate S Hill,Yihu Xie,Yi Ren
Cryo-EM structure of the CBC-ALYREF complex
eLife
2024-09-16
Brian J Woo,Ruhollah Moussavi-Baygi,Heather Karner,Mehran Karimzadeh,Hassan Yousefi,Sean Lee…
Integrative identification of non-coding regulatory regions driving metastatic prostate cancer
Cell reports
2024-09-14
Mackenzie L Hagan,Anik Tuladhar,Kanglun Yu,Dima W Alhamad,Husam Bensreti,Jennifer Dorn,Victor M…
Osteocyte Sptbn1 Deficiency Alters Cell Survival and Mechanotransduction Following Formation of Plasma Membrane Disruptions (PMD) from Mechanical Loading
Calcified tissue international
2024-09-14
Mauro Cozzolino,Yagmur Ergun,Denis A Seli,Sonia Herraiz
Intraovarian PRP injection improves oocyte quality and early embryo development in mouse models of chemotherapy-induced diminished ovarian reserve
Aging
2024-09-14
Shivansh Kaushik,Ta I Hung,Chia-En A Chang
Molecular mechanics studies of factors affecting overall rate in cascade reactions: Multi-enzyme colocalization and environment
Protein science : a publication of the Protein Society
2024-09-14
Gabriella O Estevam,Edmond M Linossi,Christian B Macdonald,Carla A Espinoza,Jennifer M Michaud…
Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain
eLife
2024-09-13
Khaled Mohamed Nassar,Xue Yang,Adriana Baker,Rahul Gopalam,William C Arnold,Timilehin T Adeniran…
PELP1 Is a Novel Therapeutic Target in Hepatocellular Carcinoma
Cancer research communications
2024-09-11
Salik Hussain,Nairrita Majumder,Md Habibul Hasan Mazumder,Sara E Lewis,Olanrewaju Olapeju,Murugesan…
Intermittent ozone inhalation during house dust mite-induced sensitization primes for adverse asthma phenotype
Redox biology
2024-09-08
Mark D Straub,Erik T Ouellette,Michael A Boreen,Jacob A Branson,Alex Ditter,A L David Kilcoyne…
Correction: Thorium amidates function as single-source molecular precursors for thorium dioxide
Chemical communications (Cambridge, England)
2024-09-06
Anirban Ghoshal,Kesatebrhan Haile Asressu,Mohammad Anwar Hossain,Peter J Brown,Meganathan…
Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity
Journal of medicinal chemistry
2024-09-05
Elizabeth C Lewandowski,Colin B Arban,Morgan P Deal,Andrea L Batchev,Matthew J Allen
Europium(II/III) coordination chemistry toward applications
Chemical communications (Cambridge, England)
2024-09-04
Adam P Moyer,Theresa A Ramelot,Mariano Curti,Margaret A Eastman,Alex Kang,Asim K Bera,Roberto…
Enumerative Discovery of Noncanonical Polypeptide Secondary Structures
Journal of the American Chemical Society
2024-09-04
Adi N R Poli,Ian Tietjen,Nitesh K Nandwana,Joel Cassel,Troy E Messick,Emery T Register,Frederick…
Design of novel and highly selective SARS-CoV-2 main protease inhibitors
Antimicrobial agents and chemotherapy
2024-09-03
Nur-E Alom,Neha Rani,H Bernhard Schlegel,Hien M Nguyen
Highly stereoselective synthesis of α-glycosylated carboxylic acids by phenanthroline catalysis
Organic chemistry frontiers : an international journal of organic chemistry
2024-08-30
Elijah T Roberts,Alexander R Davis,Jeremy T Risher,Adam W Barb,I Jonathan Amster
Automated Assignment of 15 N And 13 C Enrichment Levels in Doubly-Labeled Proteins
Journal of the American Society for Mass Spectrometry
2024-08-30
Michael A Pitino,Deborah L O'Connor,Sharon Unger,Bum Jin Kim,Alain Doyen,Md Abdul Wazed…
Comparative proteomic analysis of donor human milk treated by high-pressure processing or Holder pasteurization on undigested proteins across dynamic simulated preterm infant digestion
Food chemistry
2024-08-29
Zachary J Kirsch,Jonathan Ashby,Richard W Vachet
Investigating Protein-Nucleic Acid Binding Interactions with Diethylpyrocarbonate Covalent Labeling-Mass Spectrometry
Journal of the American Society for Mass Spectrometry
2024-08-29
Junji Zhu,GuanQun Liu,Zuberwasim Sayyad,Christopher M Goins,Shaun R Stauffer,Michaela U Gack
ISGylation of the SARS-CoV-2 N protein by HERC5 impedes N oligomerization and thereby viral RNA synthesis
Journal of virology
2024-08-28
Zaineb Javed,Dong Hui Shin,Weihua Pan,Sierra R White,Amal Taher Elhaw,Yeon Soo Kim,Shriya…
Drp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression
EMBO reports
2024-08-27
Wendy Sun,Anne Billot,Jingnan Du,Xiangyu Wei,Rachel A Lemley,Mohammad Daneshzand,Aapo Nummenmaa…
Precision Network Modeling of Transcranial Magnetic Stimulation Across Individuals Suggests Therapeutic Targets and Potential for Improvement
medRxiv : the preprint server for health sciences
2024-08-26
Ying-Hui Ko,Ravi K Lokareddy,Steven G Doll,Daniel P Yeggoni,Amandeep Girdhar,Ian Mawn,Joseph R Klim…
Single Acetylation-mimetic Mutation in TDP-43 Nuclear Localization Signal Disrupts Importin α1/β Signaling
Journal of molecular biology
2024-08-24
Andrew W L Rogers,Lauren C Radlinski,Henry Nguyen,Connor R Tiffany,Thaynara Parente Carvalho,Hugo L…
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota
Cell host & microbe
2024-08-24
Ruoxi Wu,Shakti Ingle,Sarah A Barnes,Heather R Dahlin,Susmita Khamrui,Yufei Xiang,Yi Shi,David H…
Structural insights into RNA cleavage by a novel family of bacterial RNases
Nucleic acids research
2024-08-24
Anthony Maxwell,Grace Swanson,Annie Thy Nguyen,Anna Hu,Darby Richards,Yuan You,Laura Stephan,Marcia…
Hydroquinone impairs trophoblast migration and invasion via AHR-twist-IFITM1 axis
Placenta
2024-08-22
Meagan N Esbin,Liza Dahal,Vinson B Fan,Joey McKenna,Eric Yin,Xavier Darzacq,Robert Tjian
TFEB controls expression of human syncytins during cell-cell fusion
Genes & development
2024-08-21
Ying-Jiun C Chen,Govinal Badiger Bhaskara,Yue Lu,Kevin Lin,Sharon Y R Dent
The SAGA acetyltransferase module is required for the maintenance of MAF and MYC oncogenic gene expression programs in multiple myeloma
Genes & development
2024-08-21
Michael A Funk,Christina M Zimanyi,Gisele A Andree,Allison E Hamilos,Catherine L Drennan
How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase
Biochemistry
2024-08-20
Ben Johnson,Maria Iuliano,TuKiet T Lam,Thomas Biederer,Pietro V De Camilli
A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell-cell contacts
The Journal of cell biology
2024-08-19
Sophia P M Sok,Kaitlyn Pipkin,Narcis I Popescu,Megan Reidy,Bin Li,Holly Van Remmen,Mike Kinter,Xiao…
Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis
Journal of immunology (Baltimore, Md. : 1950)
2024-08-19
Ruiqin Zhong,Dayong Zhou,Dennis R Phillips,Earle R Adams,Lirong Chen,John P Rose,Bi-Cheng Wang…
Identification of glycosyltransferases mediating 2-O-arabinopyranosyl and 2-O-galactosyl substitutions of glucuronosyl side chains of xylan
The Plant journal : for cell and molecular biology
2024-08-15
Carolyn M Ott,Sandii Constable,Tri M Nguyen,Kevin White,Wei-Chung Allen Lee,Jennifer Lippincott…
Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons
The Journal of cell biology
2024-08-13
David K Dansu,Ipek Selcen,Sami Sauma,Emily Prentice,Dennis Huang,Meng Li,Sarah Moyon,Patrizia…
Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
The Journal of cell biology
2024-08-12
Amanda C Del Giacco,Angelica M Morales,Scott A Jones,Samantha J Barnes,Bonnie J Nagel
Ventral striatal-cingulate resting-state functional connectivity in healthy adolescents relates to later depression symptoms in adulthood
Journal of affective disorders
2024-08-12
Alaina M Wojciechowski,Brent A Bell,Ying Song,Brandon D Anderson,Alexa Conomikes,Cecilia Petruconis…
Inducible RPE-specific GPX4 knockout causes oxidative stress and retinal degeneration with features of age-related macular degeneration
Experimental eye research
2024-08-11
Cleison Ledesma Taira,Lucas Dos Santos Dias,Sarah Lichtenberger,Alexander J Whitehead,Brenda…
Vaccination with O-linked Mannans Protects against Systemic Candidiasis through Innate Lymphocyte Populations
Journal of immunology (Baltimore, Md. : 1950)
2024-08-07
Stephanie Grebinoski,Gwenyth Pieklo,Qianxia Zhang,Anabelle Visperas,Jian Cui,Jordana Goulet,Hanxi…
Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells
Journal of immunology (Baltimore, Md. : 1950)
2024-08-07
C Elizabeth Adams,Sabrina K Spicer,Jennifer A Gaddy,Steven D Townsend
Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties
ACS infectious diseases
2024-08-06
Pablo Lara-Gonzalez,Smriti Variyar,Shabnam Moghareh,Anh Cao Ngoc Nguyen,Amrutha Kizhedathu…
Cyclin B3 is a dominant fast-acting cyclin that drives rapid early embryonic mitoses
The Journal of cell biology
2024-08-06
Michelle W Voss,Chris Oehler,Will Daniels,Matthew Sodoma,Bryan Madero,James Kent,Shivangi Jain…
Exercise effects on brain health and learning from minutes to months: The brain EXTEND trial
Contemporary clinical trials
2024-08-02
Xun Wu,Ziyi Wang,Tyler Shern,Hanrui Zhang
Efferocytosis assay to quantify the engulfment and acidification of apoptotic cells by macrophages using flow cytometry
STAR protocols
2024-07-28
Uttam M Shrestha,Hee-Don Chae,Qizhi Fang,Randall J Lee,Juliet Packiasamy,Lyna Huynh,Joseph Blecha…
A Feasibility Study of [18 F]F-AraG Positron Emission Tomography (PET) for Cardiac Imaging-Myocardial Viability in Ischemia-Reperfusion Injury Model
Molecular imaging and biology
2024-07-26
Orangel J Gutierrez Fugón,Osman Sharifi,Nicholas Heath,Daniela C Soto,J Antonio Gomez,Dag H Yasui…
Integration of CTCF loops, methylome, and transcriptome in differentiating LUHMES as a model for imprinting dynamics of the 15q11-q13 locus in human neurons
Human molecular genetics
2024-07-24
Craig A McElroy,Elihu C Ihms,Deepak Kumar Yadav,Melody L Holmquist,Vibhuti Wadhwa,Vicki H Wysocki…
Solution structure, dynamics and tetrahedral assembly of Anti-TRAP, a homo-trimeric triskelion-shaped regulator of tryptophan biosynthesis in Bacillus subtilis
Journal of structural biology: X
2024-07-22
Hooman Bagheri,Hana Friedman,Amanda Hadwen,Celia Jarweh,Ellis Cooper,Lawrence Oprea,Claire Guerrier…
Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells
Glia
2024-07-18
Stefanie F Valbon,Marie-Eve Lebel,H Alex Feldman,Stephanie A Condotta,Mengqi Dong,Daniela Giordano…
Type I interferon induced during chronic viral infection favors B-cell development in the thymus
Immunology and cell biology
2024-07-15
Jun Yang,Biyue Zhu,Jing Zhang,Steven H Liang,Shiqian Shen,Chongzhao Ran
Half-Curcumin-Based Chemiluminescence Probes and Their Applications in Detecting Quasi-Stable Oxidized Proteins
Angewandte Chemie (International ed. in English)
2024-07-09
Ashley E Trojniak,Vuong Q Dang,Kerri M Czekner,Robin J Russo,Lilyan M Mather,Edward L Stahl,Michael…
Synthesis and evaluation of 3,4,5-trisubstituted triazoles as G protein-biased kappa opioid receptor agonists
European journal of medicinal chemistry
2024-07-06
Chunhui Tian,Hongwei Cai,Zheng Ao,Longjun Gu,Xiang Li,Vivian C Niu,Maria Bondesson,Mingxia Gu,Ken…
Engineering human midbrain organoid microphysiological systems to model prenatal PFOS exposure
The Science of the total environment
2024-07-04
Young A Yoo,Songhua Quan,William Yang,Qianyu Guo,Yara Rodríguez,Zachary R Chalmers,Mary F Dufficy…
Asparagine Dependency Is a Targetable Metabolic Vulnerability in TP53-Altered Castration-Resistant Prostate Cancer
Cancer research
2024-07-03
Dylan J Martini,Katherine B Case,Derrik Gratz,Kathryn Pellegrini,Elizabeth Beagle,Thomas Schneider…
PD-L1 and nectin-4 expression and genomic characterization of bladder cancer with divergent differentiation
Cancer
2024-07-03
Ivan Guerrero,Belem Yoval-Sánchez,Csaba Konrad,Giovanni Manfredi,Ilka Wittig,Alexander Galkin
Sex-dependent differences in macaque brain mitochondria
Biochimica et biophysica acta. Bioenergetics
2024-07-03
Wendy M McKimpson,Sophia Spiegel,Maria Mukhanova,Michael Kraakman,Wen Du,Takumi Kitamoto,Junjie Yu…
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells
The Journal of cell biology
2024-07-03
Tihana Trsan,Vincent Peng,Chirag Krishna,Takahiro E Ohara,Wandy L Beatty,Raki Sudan,Masahiro Kanai…
The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
Developmental cell
2024-06-28
Bojian Hou,Zixuan Wen,Jingxuan Bao,Richard Zhang,Boning Tong,Shu Yang,Junhao Wen,Yuhan Cui,Jason H…
Interpretable deep clustering survival machines for Alzheimer's disease subtype discovery
Medical image analysis
2024-06-28
Gabrielle Zuniga,Sakie Katsumura,Jasmine De Mange,Paulino Ramirez,Farzaneh Atrian,Masahiro Morita…
Pathogenic tau induces an adaptive elevation in mRNA translation rate at early stages of disease
Aging cell
2024-06-27
Karan Vishwanath,Scott R McClure,Lawrence J Bonassar
Heterogeneous distribution of viscosupplements in vivo is correlated to ex vivo frictional properties of equine cartilage
Journal of biomedical materials research. Part A
2024-06-26
John M Drago,Bastien Guerin,Jason P Stockmann,Lawrence L Wald
Multiphoton parallel transmission (MP-pTx): Pulse design methods and numerical validation
Magnetic resonance in medicine
2024-06-20
Tyler C Diorio,Vidhya Vijayakrishnan Nair,Neal M Patel,Lauren E Hedges,Vitaliy L Rayz,Yunjie Tong
Real-time quantification of in vivo cerebrospinal fluid velocity using the functional magnetic resonance imaging inflow effect
NMR in biomedicine
2024-06-17
Jennifer L Anderson,Jayden A McGreer,Sarah M Tremble,Abigayle V Tainter-Gilbert,Marilyn J Cipolla
Differential Effects of LOX-1 Inhibition on Aortic Structure and Posterior Cerebral Artery Structure and Function in an Experimental Model of Preeclampsia
Reproductive sciences (Thousand Oaks, Calif.)
2024-06-10
Christopher W Davies-Jenkins,Helge J Zöllner,Dunja Simicic,Steve C N Hui,Yulu Song,Kathleen E…
GABA-edited MEGA-PRESS at 3 T: Does a measured macromolecule background improve linear combination modeling?
Magnetic resonance in medicine
2024-05-31
Ming Li,Sebastian Freeman,Janusz Franco-Barraza,Kathy Q Cai,Amy Kim,Sha Jin,Edna Cukierman,Kaiming…
A bioprinted sea-and-island multicellular model for dissecting human pancreatic tumor-stroma reciprocity and adaptive metabolism
Biomaterials
2024-05-30
Diana Diaz,Kensey Bergdorf,Matthew A Loberg,Courtney J Phifer,George J Xu,Quanhu Sheng,Sheau-Chiann…
Wnt/β-catenin signaling is a therapeutic target in anaplastic thyroid carcinoma
Endocrine
2024-05-28
Sule Sahin,Marie Frederikke Garnæs,Anna Bennett,Nicholas Dwork,Shuyu Tang,Xiaoxi Liu,Manushka…
A pharmacokinetic model for hyperpolarized 13 C-pyruvate MRI when using metabolite-specific bSSFP sequences
Magnetic resonance in medicine
2024-05-22
Ulviyya Askerova,Yusif Abdullayev,Namiq Shikhaliyev,Abel Maharramov,Valentine G Nenajdenko,Jochen…
Computational exploration of the copper(I)-catalyzed conversion of hydrazones to dihalogenated vinyldiazene derivatives
Journal of computational chemistry
2024-05-17
Edward Anderton,Manish Chamoli,Dipa Bhaumik,Christina D King,Xueshu Xie,Anna Foulger,Julie K…
Amyloid β accelerates age-related proteome-wide protein insolubility
GeroScience
2024-05-16
Yongzhen Liu,Stephanie Maya,Sebastian Carver,Aoife K O'Connell,Anna E Tseng,Hans P Gertje…
Development of a dual channel detection system for pan-genotypic simultaneous quantification of hepatitis B and delta viruses
Emerging microbes & infections
2024-04-30
Lauren M DePoy,Kaitlyn A Petersen,Wei Zong,Kyle D Ketchesin,Ross C Matthaei,RuoFei Yin,Megan S…
Cell-type and sex-specific rhythmic gene expression in the nucleus accumbens
Molecular psychiatry
2024-04-27
Ajna Hamidovic,Sunni Mumford,Enrique Schisterman,John Davis,Fatimata Soumare
Neuroactive steroid hormone trajectories across the menstrual cycle in premenstrual dysphoric disorder (PMDD): the PHASE study
Molecular psychiatry
2024-04-25
Kai Xu,Chioma Nnyamah,Nupur Pandya,Nadia Sweis,Irene Corona-Avila,Medha Priyadarshini,Barton…
β cell acetate production and release are negligible
Islets
2024-04-12
Jessica I Lundin,Ulrike Peters,Yao Hu,Farah Ammous,Christy L Avery,Emelia J Benjamin,Joshua C Bis…
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations
Epigenetics
2024-04-04
Maria Koromina,Ashvin Ravi,Georgia Panagiotaropoulou,Brian M Schilder,Jack Humphrey,Alice Braun,Tim…
Fine-mapping genomic loci refines bipolar disorder risk genes
medRxiv : the preprint server for health sciences
2024-02-26
Caiyun Liao,Benjamin William Walters,Marcello DiStasio,Bluma J Lesch
Human-specific epigenomic states in spermatogenesis
Computational and structural biotechnology journal
2024-01-26
Fabiola Mondragón-Rosas,Luis E Florencio-Martínez,Gino S Villa-Delavequia,Rebeca G Manning-Cela…
Characterization of Tau95 led to the identification of a four-subunit TFIIIC complex in trypanosomatid parasites
Applied microbiology and biotechnology
2024-01-11
Alba Escalera,Manon Laporte,Sam Turner,Umut Karakus,Ana S Gonzalez-Reiche,Adriana van de Guchte…
The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity
Emerging microbes & infections
2023-12-19
Dongyu Wang,Alexandra Scalici,Yanbing Wang,Honghuang Lin,Achilleas Pitsillides,Nancy Heard-Costa…
Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP)
medRxiv : the preprint server for health sciences
2023-11-14
K M Koss,T Son,C Li,Y Hao,J Cao,M A Churchward,Z J Zhang,J A Wertheim,R Derda,K G Todd
Toward discovering a novel family of peptides targeting neuroinflammatory states of brain microglia and astrocytes
Journal of neurochemistry
2023-05-12