Nonhuman Primate Reagent Resource
Grant Number: P40OD028116
Research Emphasis/Objectives
The objective of the NIH Nonhuman Primate Reagent Resource is to facilitate the use of nonhuman primate (NHP) models for disease by providing primate-specific antibody reagents for targeting cell subsets, cell receptors, soluble mediators, and immunoglobulins of the most common primate species used in research. The resource supports the development of reagents specific for NHP proteins or immunoglobulins and optimizes existing reagents intended for in vitro diagnostics or for in vivo use in NHPs.
Current Research
Current research explores methods for generating and engineering recombinant antibodies against NHP targets and expressing these antibodies at large scale. The NIH Nonhuman Primate Reagent Resource also facilitates studies on the comparative structure and function of immunoglobulins from different primate species.
Services Provided
The resource provides antibodies for in vivo administration and in vitro diagnostics in NHPs. A database of commercial reagents that cross-react with 12 different NHP species is maintained on the website. The resource also provides NHP recombinant proteins, immunoglobulin reference reagents, and cell lines.
Contact Information
17 Briden Street
Worcester, MA 01605
https://www.nhpreagents.org
Principal Investigator
Diogo Magnani, Ph.D.
Director
Email: [email protected]
Additional Contact(s)
Julia Vasconcellos, Ph.D.
Senior Program Manager
Email: [email protected]